Compare the Top Medical Practice Management Software for Mac as of March 2026

What is Medical Practice Management Software for Mac?

Medical practice management software helps healthcare practices streamline day-to-day operations such as appointment scheduling, patient registration, insurance and billing, and financial reporting. It centralizes patient records, provider schedules, claim submissions, and payments into a unified platform to reduce administrative burden and improve accuracy. Many solutions integrate with electronic health records (EHR) or electronic medical records (EMR) systems, automate revenue cycle management, and support compliance with regulations like HIPAA. With features like patient portals, telehealth integration, and analytics dashboards, the software enhances both practice efficiency and patient experience. Overall, medical practice management software frees up staff time, boosts operational productivity, and allows providers to focus more on delivering quality patient care. Compare and read user reviews of the best Medical Practice Management software for Mac currently available using the table below. This list is updated regularly.

  • 1
    AZZLY

    AZZLY

    AZZLY

    AZZLY Rize is the premier clinical and business platform for addiction treatment and mental health organizations. As an all-in-one substance use disorder and mental health specific EHR, Patient Engagement and RCM platform, we serve small, medium, and large clinics. Key features for OUTPATIENT Programs include: scheduling, appointment reminder, Zoom telehealth, treatment plans, progress notes, assessments and surveys. For RESIDENTIAL programs: census, medication management, bed board, withdrawal management, DrFirst e-prescribing, EPCS, PDMP, labs. For all levels of care: alerts, patient engagement portal, electronic billing and claims submission built in. AZZLY Rize empowers your staff through its 5 star training and support services, its simplicity and automation. As a true all-in-one EHR/PM/RCM platform, improved compliance, workflow and accurate billing are achieved real-time. We proudly serve programs in over 33 states and are hosted in Microsoft Azure's private cloud network.
    Starting Price: $50/user/month
  • 2
    Zanda

    Zanda

    Zanda Health

    Zanda (formerly Power Diary) is the online practice management software trusted by health practitioners worldwide. It includes calendar management, appointment reminders (SMS + email), customisable treatment note templates, client invoicing & payments, online bookings, 2-way SMS chat, Telehealth, an in-platform practice operations manual, and a lot more! Plus, it integrates with Xero, Mailchimp, Stripe, Physiotrack, Medicare (AU) and other systems. Zanda clients range from sole practitioners to large, multi-location practices and are typically physiotherapists, psychologists, speech therapists, podiatrists, massage therapists, naturopaths, osteopaths, chiropractors, or counsellors, etc. Zanda offers a 12-month Money-Back Guarantee to help make the decision easier. They also provide very high-quality support and will manage the import of your data for you.
    Starting Price: $9.50/month/practitioner
  • 3
    NextGen Healthcare EHR

    NextGen Healthcare EHR

    NextGen Healthcare

    NextGen Healthcare provides ambulatory practices of all sizes award-winning solutions along with dedicated support and professional services. We align with your goals to achieve the success that results in healthier patients and happier providers. NextGen® Enterprise EHR offers your practice configurable clinical content, intuitive workflows, and an integrated patient experience platform that incorporates telehealth. With NextGen® Mobile, your providers’ smartphones become an extension of your EHR, which saves valuable time. Managed cloud hosting keeps your practice secure and makes upgrades easy, though on-premise options are also available. NextGen® Office is a cloud-based EHR designed to support your practice growth, save staff time, and increase patient volume. This fully integrated clinical and billing platform features specialty-specific EHR content, mobile accessibility, a revenue cycle management system, and a convenient patient portal.
  • 4
    OptiMantra

    OptiMantra

    OptiMantra

    OptiMantra is an EMR and practice management platform focused on helping integrative and wellness practices. It serves individual and multi-modality group practices of direct and primary care providers, acupuncturists, nurse practitioners, naturopaths, chiropractors, massage therapists, PTs, dieticians and nutritionists, aesthetics, and others across the US and Canada. It is a HIPAA and PHIPA-compliant platform and is highly adaptable and robust - it includes online appointment booking, patient messaging and email reminders, a patient portal, intake forms and customizable charting, integrated payment processing, integrated labs and imaging, insurance billing, in-program tele-health, inventory management, and more. The platform is cloud-based and accessible and usable via any desktop, laptop, tablet or phone with internet access.
    Starting Price: $99 per month
  • 5
    CureMD

    CureMD

    CureMD

    Transform your practice with CureMD's cloud-based Electronic Health Record in a way you never imagined before. With a powerful knowledge base, CureMD is built for usability, performance, and reliability. It delivers advanced features, previously available in systems costing thousands of dollars, at a fraction of the cost. Version 10g includes an iPad app that works delightfully. It is intuitive, simple, and enjoyable. You have complete access to your appointments, clinical reviews, patient notes, medical histories, and document manager - all bundled in one app. Integrated access across patient demographics, scheduling, electronic billing, administrative/financial reporting and workflow management connects front and back office operations, improves productivity eliminates reimbursement delays and communication barriers.
    Starting Price: $295 per month
  • 6
    PracticeHarmony

    PracticeHarmony

    Mahler Health

    Practice Harmony is the premier practice management tool for running your healthcare practice. Our cloud-based practice management software solution streamlines your practice's operations and optimizes your workflow. Robust scheduling, advanced EHR, customized forms, patient dashboard, optimized voice-to-text, full RCM, TeleMedicine, TelePsychiatry, eRx, HIPAA Compliant CRM, and so much more. Streamlined operations require the perfect orchestration of efficient patient scheduling, proper documentation, and successful billing. Run your entire practice from scheduling to billing with just one log-in. Schedule a demo today to learn how you can bring Harmony to your Practice.
  • 7
    Mercury Medical
    Awarded among the Top 10 MPM and RCM solutions, Mercury Medical is a robust medical billing solution. With over 400 customizable reports, built in Scheduler and Patient Portal, Mercury Medical is the perfect solution for major billing, suitable for multiple specialties and RCM processes Mercury Medical is a reliable, proven professional Accounts Receivable solution that will reduce processing times, shorten payment cycles and increase cash flow. Mercury Medical is fully configurable to any vertical or process including: Anesthesiology, University, Physical Therapy, and more. Mercury Products are HIPAA compliant with a guaranteed connection to any clearinghouse or insurance company. Mercury Medical’s automated job system will facilitate a daily system tune-up: housecleaning; folder maintenance; daily backups; 837 exports; 835 imports; HL7. All subscriptions come with the expert help of CrisSoft Support.
    Starting Price: $440.00
  • 8
    MediOffice

    MediOffice

    MediOffice

    We are always open to ways to improve the software and welcome ideas. If you have an idea you would like to propose then please use our “Raise a Ticket” feature. Our training team are experts, not just at MediOffice but hugely experienced in the healthcare industry, and are happy to provide first-class training to you and your team. We have the experience, tools and expertise to successfully migrate your existing patient demographics and clinical history documentation from other practice management systems to MediOffice. To make the best use of your investment in MediOffice, it is essential that all the members of your team are properly trained. Our training team are experts, not just at MediOffice but hugely experienced in the healthcare industry. If you are looking to modernise your practice or have outgrown your current practice management software, we are here to provide a seamless migration to Medioffice.
    Starting Price: $113.99 per user per month
  • 9
    PrognoCIS

    PrognoCIS

    Bizmatics Inc

    PrognoCIS EHR is designed to empower healthcare providers with customizable templates that adapt to their unique workflows, ensuring efficiency and precision in patient care. With dynamic features like Patient Portal, Medical Billing, Revenue Cycle Management (RCM), and e-Prescription, PrognoCIS simplifies daily operations, allowing physicians to focus more on their patients. Built for seamless accessibility across all devices, PrognoCIS offers a comprehensive suite of solutions, including Practice Management, Telemedicine, Medical Credentialing, e-Faxing, and Secure Messaging. Our robust library of pre-built forms and templates provides extensive customization options, enabling clinics to streamline documentation with minimal effort. Experience the power of tailored EHR solutions designed to enhance productivity, optimize workflows, and improve patient engagement. Let us demonstrate how PrognoCIS can transform your practice with cutting-edge technology and intuitive usability.
  • 10
    Advaa Health

    Advaa Health

    Advaa Health

    "Advaa Health is an all-in-one medical practice management and digital health platform designed to simplify the daily workflow of primary care physicians. We eliminate administrative overload, streamline patient management, and help practices deliver faster, higher-quality care without increasing staff burden or operational costs. Built for modern primary care—including Direct Primary Care (DPC), virtual primary care, and hybrid clinic models—Advaa Health provides flexible, automated workflows that reduce charting time, improve care coordination, and keep your practice running efficiently. Our clinical modules, including Remote Patient Monitoring (RPM), Chronic Care Management (CCM), and Behavioral Health EMR, give PCPs the tools to manage chronic conditions, track care plans, and extend care between visits while maintaining compliance and generating predictable monthly revenue. The Advaa Health platform integrates electronic prescribing, medical appointment scheduling, EHR, l
    Starting Price: $99/month
  • 11
    Herfert Software

    Herfert Software

    Herfert Chiropractic Software

    Enjoy a fast, easy-to-learn interface with simple navigation for both doctors & staff. Automatic posting, visit entry, & self check-in/out. Cloud access, Fast SOAP Notes & front desk, billing, text appointment reminders, KIOSK, powerful tickler & patient correspondence. Top rated customer support! We do it all at an affordable price. Easily manage small, large & multiple chiropractic offices. Since 1980 we have provided a superior easy-to-use patient management system that no one else can match!
  • 12
    Vozo EHR
    Vozo is the industry-leading EHR platform that empowers healthcare professionals to manage their practices with advanced, informed, personalized care. Vozo platform offers an outstanding combination of ease of use and affordability, specifically tailored to enhance innovative practice workflow management. Safely and securely manage your patient records on Vozo's unified cloud-based EHR software, ensuring streamlined operations and comprehensive care. Additionally, it offers advanced features like easy-to-access dashboards, online telehealth appointments, customizable documentation, secure bill pay, dedicated messenger, extensive lab integration, automated electronic claim submission, and more.
    Starting Price: $114 per month
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