Compare the Top Endpoint Protection Software for Startups as of March 2026

What is Endpoint Protection Software for Startups?

Endpoint protection software is a software platform that provides the solution to secure endpoints—such as laptops, desktops, smartphones, and tablets—against cyber threats and attacks. These platforms provide real-time monitoring and defense mechanisms to protect devices from malware, ransomware, phishing, and other types of threats. Endpoint protection software typically includes antivirus, anti-malware, firewall, encryption, and intrusion prevention features to prevent unauthorized access and ensure data security. It also allows for centralized management, enabling IT teams to enforce security policies, update software, and monitor the health of all devices in the network. By using endpoint protection software, organizations can safeguard their devices and networks from cyber risks while maintaining compliance with security standards. Compare and read user reviews of the best Endpoint Protection software for Startups currently available using the table below. This list is updated regularly.

  • 1
    DriveStrike

    DriveStrike

    DriveStrike

    DriveStrike is easy to use, implement and manage. With DriveStrike you can execute secure remote wipe, remote lock, and remote locate commands on any platform. Integrated drive encryption support as well as mobile device management MDM for mobile platforms. Our professional support team is always available to answer your questions and help you install our services or manage your account and devices. Protecting your data and devices has never been easier or more cost effective. If you have questions or need help understanding how best to protect your data please contact us and we will gladly answer your questions. Protect your business with a device and data protection platform that keeps all devices safe with a single solution and Dashboard. Keep your Workstations, MacBooks, iPads, Smartphones, Tablets, Laptops safe, secure, and organized.
    Starting Price: $0.99 per month
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  • 2
    ThreatLocker

    ThreatLocker

    ThreatLocker

    The ThreatLocker suite of security tools are powerful and designed so that everyone from businesses to government agencies to academic institutions can directly control exactly what applications run on their networks. We envision a future in which all organizations can chart their own course free from the influence of cybercriminals and the damage their incursions cause, and our team of veteran cybersecurity professionals created ThreatLocker to make this vision a reality. The team at ThreatLocker has been developing cybersecurity tools for decades, including programs to enhance email and content security, and this is our most innovative and ambitious cybersecurity solution yet. We developed this unique cybersecurity system because we believe that organizations should have complete control of their networks and should not have to live in fear of the next malware attack. To learn more, visit ThreatLocker.com.
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  • 3
    NinjaOne

    NinjaOne

    NinjaOne

    NinjaOne enhances endpoint protection through monitoring, patching, and software controls. Automated alerts flag suspicious behavior or unauthorized applications. Regular patching keeps devices protected from vulnerabilities. Remote commands allow technicians to remediate threats instantly. Backup features add an extra layer of security against ransomware. Centralized reporting provides insights into endpoint security posture. NinjaOne ensures endpoints remain safe and compliant.
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  • 4
    UTunnel VPN and ZTNA
    UTunnel provides Cloud VPN, ZTNA, and Mesh Networking solutions for secure remote access and seamless network connectivity. ACCESS GATEWAY: Our Cloud VPN as a Service offers swift deployment of Cloud or On-Premise VPN servers. It utilizes OpenVPN and IPSec protocols, enables policy-based access control, and lets you deploy a Business VPN network effortlessly. ONE-CLICK ACCESS: A Zero Trust Application Access (ZTAA) solution that simplifies secure access to internal business applications. It allows users to securely access them via web browsers without the need for a client application. MESHCONNECT: This Zero Trust Network Access (ZTNA) and mesh networking solution based on WireGuard enables granular access controls to business network resources and easy creation of secure mesh networks. SITE-TO-SITE VPN: The Access Gateway solution lets you easily set up secure Site-to-Site tunnels (IPSec) between UTunnel's VPN servers and hardware network gateways, firewalls & UTM systems.
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    Starting Price: $6/user/month
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  • 5
    Hexnode UEM

    Hexnode UEM

    Mitsogo Inc

    Hexnode, the enterprise software division of Mitsogo Inc., is a Unified Endpoint Management solution with cross-platform functionalities. Hexnode supports all major operating systems, including iOS, iPadOS, Android, Windows, macOS, tvOS, Linux, ChromeOS, visionOS, Apple TV, Android TV, and fireOS, and offers out-of-the-box enrollment methods. The entire device lifecycle, starting from enrollment to device retirement, can be monitored and managed from a unified console. Features such as automated device enrollment, geofencing, Remote Monitoring and Management, patch management, and a simple and intuitive UI makes it the perfect tool for device management. In addition, Hexnode offers a wealth of tools perfect for today's increasingly mobile, modern teams, which includes an intuitive dashboard for greater visibility and control over mobile devices across the enterprise, web filtering for security, location tracking, and so much more.
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    GoodAccess

    GoodAccess

    GoodAccess

    GoodAccess is a cybersecurity platform (SASE/SSE) that empowers medium-sized enterprises to easily implement Zero Trust Architecture (ZTA) in their infrastructure, regardless of its complexity or scale. By leveraging a Low-Code/No-Code approach, GoodAccess delivers a hardware-free, rapid deployment solution within hours or days, allowing companies to enhance their security without the need for in-house IT experts. Our platform ensures seamless integration with modern SaaS/cloud applications as well as legacy systems, protecting critical assets for remote and hybrid workforces. GoodAccess serves businesses with 50-5000 employees across diverse industries, particularly those adopting multi-cloud and SaaS environments. Start your 14-day full-featured free trial.
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    Starting Price: $7 per user/month
  • 7
    Avast Ultimate Business Security
    Comprehensive cybersecurity and patch automation for growing businesses  Avast Ultimate Business Security includes our award-winning next-gen antivirus with online privacy tools and patch management automation software to help keep your devices, data, and applications updated and secure. Key Benefits: * Remote Management - Manage your devices and security as you scale and grow  * Device Protection - Safeguard your business devices against cyberattacks * Data Protection - Prevent ransomware and data breaches, even from the inside * Online Security and Privacy - Stay away from phishing, sniffers, scams, and other online threats * Patch Management - Save time by automatically patching software vulnerabilities 
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    Starting Price: $39.99/year/user
  • 8
    Heimdal Endpoint Detection and Response (EDR)
    Heimdal® Endpoint Detection and Response is our proprietary multi-solution service providing unique prevention, threat-hunting, and remediation capabilities. It combines some of the most advanced threat-hunting technologies: - Next-Gen Antivirus - Privileged Access Management - Application Control - Ransomware Encryption Protection - Patch & Asset Management - Email Security - Remote Desktop - Threat Prevention ( DNS based ) - Threat Hunting & Action Center With 9 modules working together seamlessly under one convenient roof, all within one agent and one platform, Heimdal Endpoint Detection and Response grants you access to all the essential cybersecurity layers your business needs to protect itself against both known and unknown online and insider threats. Our state-of-the-art product empowers you to quickly and effortlessly respond to sophisticated malware with stunning accuracy, protecting your digital assets and your reputation in the process as well.
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    Starting Price: $0/month
  • 9
    SafeDNS

    SafeDNS

    SafeDNS

    At SafeDNS, we are committed to creating a safer and more secure online environment for SMBs, enterprises, ISPs, MSPs, OEMs, and Education. We have a global footprint, making the internet safer for millions of users in over 60 countries. With years of experience in the field of cybersecurity and DNS filtering, we offer cutting-edge solutions to safeguard your digital life. At present, SafeDNS serves more than 4000 businesses and institutions, and tens of thousands of home users worldwide. We do: -Web content filtering. We help you block all dangerous or unwanted websites such as pornography, violence, child sexual abuse and similar categories. -Malware protection. We also have your back against malicious sites trying to breach user devices either with viruses or information theft intent. -Cloud service. Additionally, we provide you with a cloud filtering service that requires no additional hardware purchase or software installation.
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    Starting Price: $0.9/user/month
  • 10
    Avast Business Hub
    The Business Hub is an integrated, cloud-based security platform for businesses and IT service providers to manage all Avast Business solutions deployed in their networks. It provides real-time visibility of threats, comprehensive reporting, and management capabilities, all from a single pane of glass. Formerly known as CloudCare, the Business Hub is an easy-to-use cloud security platform with a refreshing new UI.
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    Starting Price: $36.99
  • 11
    SentinelOne Singularity
    One intelligent platform. Unprecedented speed. Infinite scale. Singularity™ enables unfettered visibility, industry-leading detection, and autonomous response. Discover the power of AI-powered, enterprise-wide cybersecurity. The world’s leading enterprises use the Singularity platform to prevent, detect, and respond to cyber attacks at machine-speed, greater scale, and higher accuracy across endpoint, cloud, and identity. SentinelOne delivers cutting-edge security with this platform by offering protection against malware, exploits, and scripts. SentinelOne cloud-based platform has been perfected to be innovative compliant with security industry standards, and high-performance whether the work environment is Windows, Mac or Linux. Thanks to constant updating, threat hunting, and behavior AI, the platform is ready for any threat.
    Starting Price: $45 per user per year
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    ManageEngine Endpoint Central
    ManageEngine Endpoint Central is built to secure the digital workplace while also giving IT teams complete control over their enterprise endpoints. It delivers a security-first approach by combining advanced endpoint protection with comprehensive management, allowing IT teams to manage the entire endpoint lifecycle, all from a single console. With automated patching across Windows, Mac, Linux and 1,000+ third-party applications, it ensures vulnerabilities are mitigated before attackers can exploit them. Its next-gen antivirus (NGAV) feature, powered by AI-driven behavioural detection, provides 24/7 protection against ransomware, malware, and zero-day threats. Endpoint Central further strengthens enterprise defenses with a broad set of security capabilities, including vulnerability assessment and mitigation, peripheral device control, data loss prevention, application control, endpoint privilege management, encryption with FileVault and BitLocker, and browser security.
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    Starting Price: $795.00/one-time
  • 13
    CrowdStrike Falcon
    CrowdStrike Falcon is a cloud-native cybersecurity platform that provides advanced protection against a wide range of cyber threats, including malware, ransomware, and sophisticated attacks. It leverages artificial intelligence (AI) and machine learning to detect and respond to threats in real time, offering endpoint protection, threat intelligence, and incident response capabilities. The platform uses a lightweight agent that continuously monitors endpoints for signs of malicious activity, providing visibility and protection without significant impact on system performance. Falcon’s cloud-based architecture ensures fast updates, scalability, and rapid threat response across large, distributed environments. Its comprehensive security features help organizations prevent, detect, and mitigate potential cyber risks, making it a powerful tool for modern enterprise cybersecurity.
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    ManageEngine Patch Manager Plus
    Keep all your production businesses up to date by automating the entire patching process using Patch Manager Plus. Available as both cloud-based and on-premise software, Patch Manager Plus offers features that include scanning for and detecting missing patches, automated scheduled patch deployments, test and approve patches, patch tracking, patch compliance and reporting. Patch Manager Plus also enables users to provide detailed audit and compliance reports.
    Starting Price: $245 per year
  • 15
    ConnectWise Cybersecurity Management
    Define and Deliver Comprehensive Cybersecurity Services. Security threats continue to grow, and your clients are most likely at risk. Small- to medium-sized businesses (SMBs) are targeted by 64% of all cyberattacks, and 62% of them admit lacking in-house expertise to deal with security issues. Now technology solution providers (TSPs) are a prime target. Enter ConnectWise Cybersecurity Management (formerly ConnectWise Fortify) — the advanced cybersecurity solution you need to deliver the managed detection and response protection your clients require. Whether you’re talking to prospects or clients, we provide you with the right insights and data to support your cybersecurity conversation. From client-facing reports to technical guidance, we reduce the noise by guiding you through what’s really needed to demonstrate the value of enhanced strategy.
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    LogMeIn Central
    LogMeIn Central is a powerful remote monitoring and management (RMM) platform designed to help IT teams maintain and secure their infrastructure from anywhere. It offers fast, reliable remote access for both PCs and Macs via mobile devices or desktops, enabling seamless support regardless of location. The platform provides features such as user management with group permissions, two-factor authentication, and computer grouping by location or function. LogMeIn Central integrates antivirus management powered by Bitdefender and a security center to help mitigate risks and prevent unauthorized data access. It also monitors computer health to detect critical issues and ensure smooth operation. Suitable for internal IT teams and managed service providers, it enables efficient management of endpoints through a single dashboard.
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    WatchGuard Endpoint Protection Platform (EPP)
    The WatchGuard EPP product goes beyond signature-based antivirus to stop malware, ransomware and threats that leverage unknown, zero day vulnerabilities. Even better, it's managed with an intuitive Cloud-based console and lightweight agent that doesn't interfere with endpoint performance. Endpoints are protected from viruses, malware, spyware and phishing with WatchGuard EPP. We use a comprehensive set of security techniques including signatures, local cache, and even our own proprietary intelligence feeds derived from the malware previously detected with our EDR products. This enables us to find zero day exploits using behavioral heuristics and known indicators of attacks as “contextual rules." WatchGuard EPP centralizes next-generation antivirus for all your Windows, macOS and Linux desktops, laptops, and servers, in addition to the leading virtualization systems.
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    FortiClient

    FortiClient

    Fortinet

    Multilayered endpoint security with behavior based analysis for prevention against known and unknown threats. Complete real-time visibility of all your global software inventory. Here, there, anywhere. Cloud-delivered FortiClient endpoint protection service designed for small and medium-sized business. Integrated endpoint protection platform that provides automated next-generation threat protection, visibility and control of your software and hardware inventory across the entire security fabric. Identify & remediate vulnerable or compromised hosts across your attack surface. As a key piece of the Fortinet Security Fabric, FortiClient integrates endpoints into the fabric for early detection and prevention of advanced threats. Security events including zero-day malware, botnet detections, and vulnerabilities are reported in real-time.
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    KACE by Quest

    KACE by Quest

    Quest Software

    KACE® by Quest supports your unified endpoint management (UEM) strategy by helping you discover and track every device in your environment, automate administrative tasks, keep compliance requirements up-to-date and secure your network from a range of cyberthreats. Discover, manage and secure all your endpoints from one console as you co-manage your traditional and modern endpoints, including Windows, Mac, Linux, ChromeOS, and iOS and Android devices. KACE is a Unified Endpoint Management solution that offers a single point of control for managing IT systems across the entire organization, inside or outside your network. This comprehensive solution takes the stress out of keeping devices secure and compliant so you can do more.
    Starting Price: As low as $3/mo/device
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    Comodo Advanced Endpoint Protection
    As Comodo Advanced Endpoint Protection (AEP) protects your endpoints against malware, the AEP application itself routinely comes under attack by malicious applications trying to circumvent its protection. Fortunately, Comodo AEP includes robust self-protection countermeasures that prevent malicious applications from gaining control or circumventing Comodo AEP services. AEP does this by intercepting system calls that might present a threat to the applications such as Terminate Process or Create Remote Thread are obvious examples of calls that might pose a risk to AEP. Other less obvious but actually more dangerous call would be CreateFile as it can do a lot more than just create a file. Comodo AEP intercepts these calls and only allows them to proceed if they won’t harm the Comodo process. Comodo AEP also contains a kernel mode driver that it uses to prevent attempts to modify the system kernel directly.
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    Kaspersky Endpoint Security
    With more of your business operations going digital, you need to protect every server, laptop and mobile device on your network. Select tier combines multi-layered technologies with flexible cloud management and centralized application, web and device controls to protect your sensitive data on every endpoint. Security shouldn’t slow you down, so our security has minimal impact on system performance. And if you’re attacked, the Remediation Engine undoes most malicious actions, so users can keep working without interruption. Delivering world-class security – including post execution Behavior Detection and Machine Learning technologies – to help reduce your attack risk and keep all your endpoints safe and secure, with less need to download frequent updates. Provides straightforward migration from third-party endpoint protection, helping to make your transition error-free. Our post-deployment quality assurance audit service will ensure optimum configuration.
    Starting Price: $40.00/one-time/user
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    SanerNow

    SanerNow

    SecPod Technologies

    SecPod SanerNow is the world's best unified endpoint security & management platform that powers IT/Security Teams automate cyber hygiene practices. It works on an intelligent agent-server model to execute effective endpoint management and security. It gives you accurate vulnerability management with scanning, detection, assessment, prioritization, and remediation capabilities. SanerNow is available on both cloud and on-premise, whose integrated patch management automates patching across all major OSs like Windows, MAC, Linux, and a vast collection of 3rd party software patches. What makes it unique? You can now access other salient features like security compliance management, IT asset management, endpoint management, software deployment, application & device control, and endpoint threat detection and response, all on a single platform. With SanerNow, you can remotely perform and automate these tasks to secure your systems from the emerging wave of cyberattacks.
    Starting Price: $50/year/device
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    Avast Small Business Solutions
    Avast Small Business Solutions deliver next-gen endpoint protection for business Windows PCs, Mac, and Windows servers that you can manage anywhere via a web browser. Our robust, easy-to-use security for devices, data, and applications is designed to keep small organizations and their employees safer online. Avast antivirus with multiple layers of security, online privacy, and remote-control features provides powerful cybersecurity controlled via a cloud-based management console. Avast Small Business Solutions are managed via cloud-based management console Avast Business Hub and consist of: * Avast Essential Business Security   * Avast Premium Business Security - combines our next-gen antivirus with VPN and USB control) * Avast Ultimate Business Security - award-winning next-gen antivirus with online privacy tools and patch management automation software
    Starting Price: $39.99/device/year
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    USB-LOCK-RP

    USB-LOCK-RP

    Advanced Systems International

    USB Control & Lockdown Software to Block USB Devices Access and Lock USB Ports in Windows Systems. Centralized USB Device Management, Monitoring and Whitelisting to Protect Computers in a Network. USB Device Control is an important part of Endpoint Security Management and focuses in the protection of computer systems and data assets from threats posed by unauthorized USB device usage. Controlling USB devices access to endpoints is required to secure networks that control machinery or store sensitive information. - Centralized USB Device Management. - Secures Groups of Computer or Specific Computers. - Whitelists Specific Devices by Hardware ID and Blocks the rest. -Automatically apply Group 1 protection settings to unassigned clients. NEW! - Receives Alerts & Logs Device Connections in the Network Automatically. -Export Status and Alerts Reports to csv format (Comma-separated value)NEW! -Automatic Authorizations Mode, Whitelist USB devices across the network automatically. NEW
    Starting Price: $20 per client/one-time
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    Emsisoft Anti-Malware
    They turn your PC into a remote-controlled zombie. Your computing power is collectively sold on the black market to send spam, attack others or store illegal content. Potentially Unwanted Programs that mess up your computer with useless browser toolbars, tons of commercials and other bulk that slows down the PC. Emsisoft Anti-Malware Home not only detects more because it uses the full power of two major antivirus- and anti-malware technologies, it also scans quicker because of the efficient combination of the scanners. Any unnecessary duplicates in detection are avoided, enabling the least impact on memory and overall hardware resources. If a user attempts to access a malicious website, Emsisoft Anti-Malware Home will immediately block the connection and prevent access. Leading privacy-conscious filtering without SSL exploitation.
    Starting Price: $19.99 per device per year
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    K7 Endpoint Security
    K7 Endpoint Security is easy to install, deploy, configure, and manage, reducing IT workload. The console for the On-premises version can be installed on any client in the network, avoiding additional investment in server hardware and software. The Cloud deployed version supports 100% remote deployment and cybersecurity management of all endpoints in the organization anytime, anywhere. K7’s international award-winning scan engine has been tested and proven to protect endpoints without affecting device performance.
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    Guardio

    Guardio

    Guardio

    Forget all about malware, phishing, and identity theft. Guardio is a lightweight extension designed to help you browse quickly and securely. It will clean your browser, speed it up, and protect your private information. How it works. Add in seconds. Remove threats. Browse as usual. Cleans the way you see the web. Removes malware, unwanted popups, and any other annoyances that ruin your day. Protects against online threats. Blocks phishing, malicious sites and scams that may result in identity theft or worse - so you can focus on what matters. Keeps your secrets secret. Be notified when personal data leaks publicly and fortify your accounts with security best practices. Under the hood. Dive deeper into the powerful technology powering Guardio. Safe web, Great technology. In order to effectively combat emerging threats from ever-evolving malicious actors, Guardio needs to stay on the bleeding edge of multiple technology disciplines. Machine Learning, Big Data, Cloud Infrastructure
    Starting Price: $9.99 per month
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    VIPRE Endpoint Security

    VIPRE Endpoint Security

    VIPRE Security Group

    VIPRE Endpoint delivers comprehensive defense against today’s sophisticated malware without the complexity of other solutions. We keep your total cost of ownership low while providing advanced security powered by machine learning, real-time behavioral analysis, and a global threat intelligence network. VIPRE combines a modern endpoint solution with time-saving efficiencies, ensuring your organization stays secure and operational. Protecting files, applications, and networks, VIPRE offers complete malware defense. It also helps enforce internet usage policies with granular controls that support employer duty-of-care. Dynamic dashboards provide real-time insights into the status of your endpoint environment, making it easier to monitor and manage security across your organization. Available as a core next-generation AV solution, a full EDR solution, or a combined EDR+MDR solution, we have a package that will work for you.
    Starting Price: $34/seat/year
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    Senturo

    Senturo

    Senturo

    Senturo safeguards Apple, Chromebook, Windows, and Android devices against loss, theft, and unauthorized access with powerful location tracking, device monitoring, and advanced recovery tools, while enhancing mobile device and data security through robust remote security policies and actions such as remote lock to protect your fleet. IT Fleet location tracking Senturo’s intuitive global map view built on Google Maps lets you monitor your entire device fleet at a glance. Pinpoint the real-time location of any device or review its movement history over the past year, ensuring you stay informed and in control. Monitoring and incident detection Ensure your devices stay where they belong. With geofencing and IP whitelisting, you’ll receive instant email alerts if a device leaves your approved area or connects to an unauthorized network, keeping your assets secure. Multi-OS messaging Send critical updates or alerts to your entire fleet in seconds.
    Starting Price: $25 per month
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    InterGuard Employee Monitoring

    InterGuard Employee Monitoring

    Awareness Technologies

    Use of employee monitoring software on company-provided devices is becoming a commonplace business practice as more and more organizations embrace the trend of allowing their workforce the flexibility to work from home, either as a full-time remote employee or as an office worker who sometimes works from home. There’s no playbook for remote work. Organizations must decide if keeping workers at home is right for them. Many companies began shifting to a work-from-home office years ago because there are many benefits to allowing employees to work remotely. Regardless of how the effects of the Coronavirus play out on the global workforce – remote work could be the new normal. The new remote work-from-home trend comes with a new set of challenges that did not exist when employees worked exclusively from the office. Employees are drawn to telecommuting because of the flexibility it provides, allowing them to maintain a better work-life balance.
    Starting Price: $8.00/month/user
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