S/R Mathematics Software for Linux

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  • 1
    R packages (maintained by YJLEE)

    R packages (maintained by YJLEE)

    R packages for PK/PD modeling , BE/BA, drug stability, ivivc, etc.

    These R packages are developed for data analysis of PK/PD modeling & simulation, bioequivalence/bioavailability (BE/BA), drug stability, in-vitro and in-vivo correlation (ivivc), as well as therapeutic drug monitoring (TDM).
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    Downloads: 26 This Week
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  • 2
    SPINA

    SPINA

    Structure parameter inference approach for endocrine feedback control

    SPINA is software for the rapid, reliable and accurate determination of constant structure parameters of endocrine feedback control systems. It is a class of static function tests that require nothing more than steady-state concentrations of hormones or metabolites obtained in vivo. The first version of this cybernetic approach had been developed for the evaluation of the functional status of the thyroid gland, i.e. thyroid's secretory capacity (gain of thyroid, GT or SPINA-GT) and sum activity of peripheral deiodinases (GD or SPINA-GD). A second version has been established for insulin-glucose homeostasis. It delivers the secretory capacity of pancreatic beta cells (SPINA-GBeta), an estimate for the insulin receptor amplification (SPINA-GR) and a static disposition index as a measure for the loop gain of the feedback loop (SPINA-DI). Both implementations of SPINA have been validated in more than 50 clinical studies based on large cohorts.
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    Downloads: 14 This Week
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  • 3

    bootf2BCA

    computing f2 bootstrap CI BCA

    Computing similarity factor (f2) bootstrap bias corrected and accelerated confidence interval
    Downloads: 16 This Week
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  • 4
    TXM

    TXM

    Unicode XML TEI text analysis platform

    TXM is a free and open-source cross-platform Unicode & XML based text analysis environment and graphical client, supporting Windows, Linux and Mac OS X. It can also be used online as a J2EE standard compliant web portal (GWT based) with access control built in. DOWNLOAD LATEST VERSION OF TXM : http://textometrie.ens-lyon.fr/spip.php?rubrique61&lang=en TXM offers a comprehensive range of analysis tools (concordances, collocate search, frequency lists, etc.) based on the powerfull CQP full text search engine (http://cwb.sourceforge.net) and a range of statistical functions (factorial analysis, classification, cooccurrency analysis, etc.) based on R packages (http://www.r-project.org). Read the scientific background at the Textométrie project web site http://textometrie.ens-lyon.fr/?lang=en. Read a full description at the TEI Tools wiki http://wiki.tei-c.org/index.php/TXM.
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    Downloads: 13 This Week
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  • 5
    NetWorkSpaces, developed by Scientific Computing Associates Inc., provides a framework to coordinate programs written in R. It allows users to write parallel programs in R easily.
    Downloads: 5 This Week
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  • 6
    The igraph library

    The igraph library

    Library for creating and manipulating graphs

    This is a library for creating and manipulating graphs with focus on speedy operations for large, sparse graphs.
    Downloads: 2 This Week
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  • 7

    libirt

    The new site is at http://psychometricon.net/libirt/

    The new site is at http://psychometricon.net/libirt/ Library of functions to estimate the items and abilities from the responses of subjects to a questionnaire. The IRT models supported are the logistic model, the multivariate logistic model, the graded model and smoothing by penalization and kernel.
    Downloads: 1 This Week
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  • 8

    runjags

    The 'runjags' R package and standalone JAGS extension module

    This package provides high-level interface utilities for MCMC models via Just Another Gibbs Sampler (JAGS), facilitating the use of parallel (or distributed) processors for multiple chains, automated control of convergence and sample length diagnostics, and evaluation of the performance of a model using drop-k validation or against simulated data. Template model specifications can be generated using a standard lme4-style formula interface to assist users less familiar with the BUGS syntax. A JAGS extension module provides additional distributions including the Pareto family of distributions, the DuMouchel prior and the half-Cauchy prior.
    Downloads: 1 This Week
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  • 9

    BiomeNet

    BAYESIAN INFERENCE OF METABOLIC DIVERGENCE AMONG MICROBIAL COMMUNITIES

    Metagenomics yields enormous numbers of microbial sequences that can be assigned a metabolic function. Using such data to infer community-level metabolic divergence is hindered by the lack of a suitable statistical framework. Here, we describe a novel hierarchical Bayesian model, called BiomeNet (Bayesian inference of metabolic networks), for inferring differential prevalence of metabolic networks among microbial communities. To infer the structure of community-level metabolic interactions, BiomeNet applies a mixed-membership modelling framework to enzyme abundance information. The basic idea is that the mixture components of the model (metabolic reactions, subnetworks, and networks) are shared across all groups (microbiome samples), but the mixture proportions vary from group to group. Through this framework, the model can capture nested structures within the data. BiomeNet is unique in modeling each metagenome sample as a mixture of complex metabolic systems (metabosystems).
    Downloads: 0 This Week
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  • 10
    A population-based method for DNA copy number analysis: recurrent copy number aberration indentification in multiple samples (with no need of single-sample calling). Developed for a quick analysis of high resolution and large population data.
    Downloads: 0 This Week
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  • 11
    Development of a common “open source” tool for assessing the accuracy of parameter estimates collected within the framework of the DCR (EU Regulation 1639/2001 and 1581/2004)
    Downloads: 0 This Week
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  • 12
    Community Detection Modularity Suite

    Community Detection Modularity Suite

    Suite of community detection algorithms based on Modularity

    - MixtureModel_v1r1: overlapping community algorithm [3], which includes novel partition density and fuzzy modularity metrics. - OpenMP versions of algorithms in [1] are available to download. - Main suite containing three community detection algorithms based on the Modularity measure containing: Geodesic and Random Walk edge Betweenness [1] and Spectral Modularity [2]. Collaborator: Theologos Kotsos. [1] M. Newman & M. Girvan, Physical Review, E 69 (026113), 2004. [2] M. Newman, Physical Review E, 74(3):036104, 2006. [3] B. Ball et al, An efficient and principled method for detecting communities in networks, 2011. The suite is based upon the fast community algorithm implemented by Aaron Clauset <aaron@cs.unm.edu>, Chris Moore, Mark Newman, and the R IGraph library Copyright (C) 2007 Gabor Csardi <csardi@rmki.kfki.hu>. It also makes of the classes available from Numerical Recipies 3rd Edition W. Press, S. Teukolsky, W. Vetterling, B. Flanne
    Downloads: 0 This Week
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  • 13

    Corbata

    CORe microBiome Analysis Tools

    Corbata is a set of statistical tools that can be used to analyze the core microbiome across a set of samples.
    Downloads: 0 This Week
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  • 14

    DEAPathways

    Differential Expression Analysis for Pathways

    This project contains the source code associated with the PLoS Computational Biology publication: "Differential Expression Analysis for Pathways". The paper text can be found here: http://www.ploscompbiol.org/article/info%3Adoi%2F10.1371%2Fjournal.pcbi.1002967
    Downloads: 0 This Week
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  • 15
    We have moved, the project is now at http://distancesampling.org
    Downloads: 0 This Week
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  • 16
    A Python library bringing together utilities I've written over the years for work in bioinformatics and biostatistics, which should be generally applicable outside these fields as well. Focuses on string processing, DBI, and math.
    Downloads: 0 This Week
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  • 17
    EnvStats

    EnvStats

    An R Package for Environmental Statistics

    EnvStats is an R package for environmental statistics. It is the open-source successor to the commercial module for S-Plus© called "EnvironmentalStats for S-Plus", which was first released in April, 1997. The EnvStats package, along with the R software environment, provides comprehensive and powerful software for environmental data analysis. EnvStats brings the major environmental statistical methods found in the literature and regulatory guidance documents into one statistical package, along with an extensive hypertext help system that explains what these methods do, how to use these methods, and where to find them in the environmental statistics literature. Also included are numerous built-in data sets from regulatory guidance documents and the environmental statistics literature. EnvStats combined with other R packages (e.g., for spatial analysis) provides the environmental scientist, statistician, researcher, and technician with tools to “get the job done!”
    Downloads: 0 This Week
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  • 18

    HPCall

    Improved base-calling for homopolymer-sensitive next-gen data.

    The current software contains the implementation for the 454 pyrosequencing platform.
    Downloads: 0 This Week
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  • 19

    Hyperspectral data analysis in R

    Handling and basic analysis of hyperspectral data in R

    The hsdar package contains classes and functions to manage, analyse and simulate hyperspectral data. These might be either spectrometer measurements or hyperspectral images through the interface of rgdal.
    Downloads: 0 This Week
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  • 20

    MCPerm: Monte Carlo SNP permutation

    Monte Carlo permutation method for SNP multiple test correlation

    MCPerm: A Monte Carlo permutation method for multiple test correlation in case-control association study Traditional permutation (TradPerm) test is an important non-parametric analysis method which can be treated as the gold standard for multiple testing corrections in case-control association study. However, it relies on the original single nucleotide polymorphism (SNP) genotypes and phenotypes data to perform a large number of random shuffles, and thus it is computationally intensive, especially for genome-wide association study (GWAS). To improve the calculation speed without changing the size of the TradPerm p-value, we developed a Monte Carlo permutation (MCPerm) method as an efficient alternative to TradPerm. Methods: MCPerm does not need to shuffle the original genotypes and phenotypes data. It uses Monte Carlo method, employs two-step hypergeometric distribution to generate the random number of genotypes (AA, Aa and aa) in cases and controls.
    Downloads: 0 This Week
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    Downloads: 0 This Week
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  • 22

    OpenM++

    OpenM++: open source microsimulation platform

    IMPORTANT: ========== Our project home page: https://openmpp.org Our latest source code and release available at: https://github.com/openmpp/main/releases/latest Our documentation available at: https://github.com/openmpp/openmpp.github.io/wiki SourceForge files still exist for historical reason. OpenM++ is an open source microsimulation platform inspired by and compatible with Modgen. OpenM++, compared to its closed source predecessor Modgen, has advantages like portability, scalability and open source. It is not a copy of Modgen, but a new, functionally equivalent implementation of the publicly available language specification.
    Downloads: 0 This Week
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  • 23
    R packages supporting parallel computing.
    Downloads: 0 This Week
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  • 24
    QRMlib provides a library of methods to investigate Quantitative Risk Management, including Market Risk, Credit Risk and Operational Risk, as developed in the book "Quantitative Risk Management: Concepts, Techniques and Tools".
    Downloads: 0 This Week
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  • 25
    A collection of code, bundled into a single R package, to perform several aspects of data management, image pre-processing, data analysis and statistical inference related to the quantitative analysis of dynamic contrast-enhanced MRI (DCE-MRI).
    Downloads: 0 This Week
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