Search Results for "ion torrent"
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Showing 10 open source projects for "ion torrent"
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TaBS-Pipe
Targeted Bisulfite Sequencing Data Analysis Pipeline v1.0.2
A pipeline to analyze the data obtained from targeted bisulfite sequencing through the ion-torrent platform. TaBSAP is a pipeline to map bisulfite treated sequencing reads to a genome of interest and perform methylation calls in a single step and enables a researcher to analyze the methylation levels of their samples straight away. It's main features are: -Bisulfite mapping and methylation calling in one single step -Supports single-end read alignments -Alignment seed length, number of mismatches etc. are adjustable -The output gives heatmap with categories. -
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AIRVF was developed to increase accuracy of low-frequency variant calling. Our zip file contains programs for both Window and Linux. AIRVF demonstrated higher precision and sensitivity by accurately detecting SNVs with low VAF in Ion Torrent data. If you cannot install Torrent Suite in non-Ubuntu Linux servers, the AIRVF and VarScan2 pipeline can be a good alternative. But combination of SNVs from VarScan2 and indels from Torrent Variant Caller-Ion Reporter will demonstrate the best performance. It's fast.
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MuffinEC
Multi-technology, INDEL aware error correction for NGS data
MuffinEC is an error correction software capable of handling all types of errors (insertion deletions, mismatches and unknown bases). It officially supports four technologies (Illumina, 454, ion Torrent and PacBio - experimental) and it also has a generic setup for others (old and/or new). It is released under LGPL version 3.0. MuffinEC can use multicore systems, thanks to its OpenMP implementation. We are developing the 2nd version of MuffinEC. The beta version is already available online. The changes are listed in the VERSION_HISTORY file. ... -
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MutAid
MutAid: Sanger and NGS based pipeline for mutation screening.
...It is capable of analyzing reads from multiple patients in a single run to create a list of potential disease causing base substitutions as well as deletions and insertions. MutAid has been developed for expert and non-expert users and supports four sequencing platforms (Sanger, Illumina, 454 and Ion Torrent) and five read mappers including BWA,TMAP, Bowtie,Bowtie2 and GSNAP and four variant callers -
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The Genome Mappability Analysis suite is used for measuring how well NGS reads can be mapped to reference genomes, especially for discovering variations
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ClAnSort
Cluster-Analysis and Sort
The ClAnSort (Cluster-Analysis and Sort) - program was written to simplify the analysis of Next Generation Sequencing (NGS) data obtained with Ion Torrent™ Technology using the BIOMED-2 Concerted Action BMH4-CT98-3936 primer sets (IGH, IGK, TRB, TRG and TRD) for amplification [van Dongen, J.J. et al., 2003]. -
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AbMining ToolBox
python scripts to analyze antibody libraries
02-14-2014. Hamming distance calculation has been updated. These are python scripts to analyze antibody libraries sequenced by next generation sequencing methods (454, Ion Torrent, MiSeq) as described in D'Angelo et al MAbs. 2014 Jan 1;6(1):160-72. -
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CallSim
low-volume read processing base corrector
CallSim is a software application that provides evidence for the validity of base calls believed to be sequencing errors and it is applicable to Ion Torrent and 454 data. CallSim provides a final classification or rescue of a base/indel in reads, where putative variants have been identified via typical SNP/indel workflows. plots rendered by: JFreeChart library http://sourceforge.net/projects/jfreechart/ -
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QUASR
Cross-platform NGS processing and analysis pipeline in Python
QUASR is a lightweight pipeline written to process and analyse next-generation sequencing (NGS) data from Illumina, 454, and Ion Torrent platforms. Although originally written for viral data, it is generic enough to work on any NGS dataset. Functions include: duplicate removal demultiplexing primer-removal quality-assurance (QA) graphing quality control (QC) consensus-generation minority-variant determination minority-variant graphing The main current version is 6.X, which is written in Python3. 7.X is my rewrite in Java, but is still work in progress. ... -
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TABSAT
Analysis Tool for Targeted Amplicon Bisulfite Sequencing
TABSAT - Targeted Amplicon Bisulfite Sequencing Analysis Tool A tool for analyzing targeted bisulfite sequencing data generated on an Ion Torrent PGM / Illumina MiSeq. The workflow starts with raw sequencing data, performs quality assessment, and uses a tailored version of Bismark to map the reads to a reference genome. Results are aggregated across all samples, presented in table format, and visualized as lollipop plots. In addition, due to the long read length of Ion Torrent reads, the pipeline is able to deduce specific methylation-patterns present in a sample. ...
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