Search Results for "clinical trials"
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Showing 24 open source projects for "clinical trials"
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SPINA
Structure parameter inference approach for endocrine feedback control
SPINA is software for the rapid, reliable and accurate determination of constant structure parameters of endocrine feedback control systems. It is a class of static function tests that require nothing more than steady-state concentrations of hormones or metabolites obtained in vivo. The first version of this cybernetic approach had been developed for the evaluation of the functional status of the thyroid gland, i.e. thyroid's secretory capacity (gain of thyroid, GT or SPINA-GT) and sum... -
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SDC
SDC facilitates development of dist. systems of medical devices.
...It is based on the upcoming SDC standard, which is specified by the IEEE in IEEE Std 11073-20702-2016 (Point-of-care medical device communication Part 20702: Medical Devices Communication Profile for Web Services), IEEE Std 11073-10207-2017 (Point-of-care medical device communication Part 10207: Domain Information and Service Model for Service-Oriented Point-of-Care Medical Device Communication), and P11073-20701 (IEEE Draft Standard for Service-Oriented Medical Device Exchange Architecture & Protocol Binding). The SDC standard has the goal to meet increasing demand for medical device interoperability in an Integrated Clinical Environment (ICE), see also ASTM F2761-1:2009. OpenSDC is not intended to be used in clinical trials, clinical studies, or in clinical routine. -
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OpenVCT
The Open-Source Virtual Clinical Trial Project
The OpenVCT project is designed to provide a common platform for performing Virtual Clinical Trials of medical imaging. OpenVCT provides tools for simulation of patient accrual and reader studies of medical imaging devices, simulating by simulating cohorts of patients and readers. OpenVCT uses common data standards, such as DICOM, to ensure inter-compatibility. -
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The new version of MinimPy (MinimPy2) is available for download at: https://osdn.net/dl/minimpy2/MinimPy2.zip Please send your feedback about this new version to mahmood.saghaei@gmail.com (include MinimPy2 in the subject) ============================================================ MinimPy is a desktop application program for sequential allocation of subjects to treatment groups in clinical trials by using the method of minimization. Comprehensive reference help is available at http://minimpy.sourceforge.net MinimPy has been fully described in the following article: Saghaei, M. and Saghaei, S. (2011) Implementation of an open-source customizable minimization program for allocation of patients to parallel groups in clinical trials. ...
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DBSolveOptimum
The software for systems biology/pharmacology modeling
...In addition to the capabilities of these software packages, DBSolveOptimum is implemented with new tools for extended data analysis and multiple simulations, which are important for simulation of virtual clinical trials and application of modern modeling techniques, like quantitative systems pharmacology, to problems arising in drug research and development. By this time, DBSolveOptimum has been successfully tested and applied for the development and analysis of both systems pharmacology and conventional PK/PD models of drugs. It is free for academic and industrial use. ... -
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PONTE is a European project standing for Efficient Patient Recruitment for Innovative Clinical Trials of Existing Drugs to other Indications. PONTE provides a platform following a Service Oriented Architecture (SOA) approach that offers intelligent automatic identification of individuals eligible to participate in clinical trials (concerning their safety and clinical trial efficacy). The trials will be designed and planned through a flexible authoring tool, enabling semantic interoperability of clinical care information systems with clinical research information systems and drug and disease knowledge databases, as well as the appliance of advanced data mining techniques and enhanced learning algorithms.
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S2O
Converting IBM SPSS files to CDISC ODM
This tool can be used to convert data collections based on IBM SPSS Statistics to the data standard for definition and exchange of clinical trials: CDISC ODM (Operational Data Model). Possible use-cases: - A project is running out of funding and scientific data collection should be performed in free available/open-source data capture systems - Advantages of reliable EDC systems like: Data security (role/right management), backup infrastructure, support of the entire clinical trial lifecycle, traceability of data (who has when entered what data or changed to what value with what reason) and compliant to regulatory requirements... -
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adLIMS
adLIMS: a Laboratory Information Management System with ADempiere
Many biological laboratories dealing with genomic samples are facing the problem of sample tracking, both for pure laboratory management and efficiency, and for internal policies, such as Good Laboratory Practices (GLP). Our laboratory exploits PCR techniques and next-generation sequencing (NGS) methods, to perform high-throughput integration site monitoring in different clinical trials and scientific projects, based on the delivery of therapeutic genes by viral vectors integrating into the genome of target cells. We process around 1500 samples/year resulting in hundreds of millions of sequencing reads, requiring automation and posing new challenges in data storage, monitoring of sample process and computational tools for analyses. ... -
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A simple grid control to mock up tables in clinical trials. Also includes 'checklog', a visual log-parser for checking SAS log files, 'sasmake', a makefiles generator, and 'graphpirate', a tool for reverse-engineering graphs.
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OxMAR
Randomisation and Minimisation for clinical trials
Online randomisation and minimisation (minimization) for allocating participants of clinical trials to a control or experimental (intervention) group. This can be done via the web and uses a series of Perl scripts. It can be accessed from anywhere using any device which can look at a web page such as a PC, tablet or mobile phone. The result of the allocation procedure is stored in a textfile, is outpt to a webpage and is emailed to the user and study administrator. -
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OptInterim
Optimal two and three stage clinical trial designs
R Package for Optimal Two and Three Stage Designs for Single-Arm and Two-Arm Randomized Controlled Trials with a Long-Term Binary Endpoint -
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De Novo Assembly From Clinical Trials
Produce high quality de novo assembly to identify pathogens.
UPDATES/ NOTICES WILL BE POSTED TO THE DISCUSSION TAB: http://sourceforge.net/p/denovoassembly/discussion/general/ Given a clinical sample, *Produce a high quality de novo assembly. *Use this assembly to identify pathogens present in the sample. *Determine pathogen significance. Data: Human... -
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Clinical Evidence Detector
Detector of clinical evidence
This is a Python program based on the NegEx algorithm that detects the polarity of the clinical evidence in clinical random trials. If you use this code please cite this paper: P. Davis-Desmond and Diego Mollá. Detection of Evidence in Clinical Research Papers (2012). Australasian Workshop On Health Informatics and Knowledge Management (HIKM 2012), Melbourne, Australia. http://www.ics.mq.edu.au/~diego/publications/hikm12.pdf -
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clinicalStudyTracker
Clinical study tracker tracks case study members through activities.
Developed at Medical Research Council UK to meet a common clinical trial need to track various types of clinical data. Users log dates of completed tasks against participant ID. Simple, useable, reduces lost data! Makes graphical progress reports. -
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This is a project associated with the Open Source SAS(r) Software Applications SourceForge project to develop a model clinical trial implementation in OpenClinica, the Open Source clinical trials system and to develop data interfaces and reporting.
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Trial Criteria Online Data Entry (trialCODE): a Java-based user interface that codifies eligibility requirements used to automate the screening of potential subjects to clinical trials. Used for caMATCH screening engine on BreastCancerTrials.org site.
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This project contains a UML2 profile for Clinical Research workflow modeling, as designed for the publication: "Standardizing Clinical Trials Workflow Representation in UML for International Site Comparison." This article was published in PLoS ONE.
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Quantitative Evalution of Blush: a program to assess myocardial reperfusion on coronary angiograms. This program calculates a value that can be used for risk classification of STEMI patients or as a surrogate endpoint in clinical trials.
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A group of statistical tools used in the development and structuring of clinical trials by the American Cancer Society. Sample size calculators.
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Web-based Electronic Data Capture (EDC) software for clinical trials. Uses XML-based data store based on CDISC ODM standard for clinical data interchange.
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CyberMedica Foundation - Improving Responsible Human Research Throughout the World by Providing an Open Systems Standard for Peer Reviewed Ethics Review and Decisioning in the Medical Research Clinical Trials Governance Process.
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iCorelab is an integrated image management system for clinical trials with a primary endpoint of performing blinded image assessments.
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