GKas
The pipeline for Genome level Ka/Ks calculation
GKas is a codon-aware DNA alignment program, which is developed based on several programs from three widely used packages: BLAT, BLASTALL (including bl2seq, formatdb and fastacmd) and PAML (including codeml). GKas can automatically detect and eliminate frame-shift mutations and premature stop-codons to compute the substitution rates (Ka, Ks and Ka/Ks) between a well-annotated genome and a non-annotated genome or even a non-well assembled scaffold data set. It is especially useful for the newly...