Alternatives to Evo 2
Compare Evo 2 alternatives for your business or organization using the curated list below. SourceForge ranks the best alternatives to Evo 2 in 2025. Compare features, ratings, user reviews, pricing, and more from Evo 2 competitors and alternatives in order to make an informed decision for your business.
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Evo Designer
Arc Institute
Evo Designer is an advanced tool developed by the Arc Institute, leveraging the capabilities of the Evo 2 genomic foundation model to facilitate DNA sequence generation and analysis. This platform enables users to input nucleotide sequences or specify organisms, prompting the model to generate corresponding DNA sequences. It provides comprehensive annotations of coding regions and, for prokaryotic sequences, offers 3D protein visualizations utilizing ESMFold. Additionally, Evo Designer evaluates sequences by scoring their perplexity and per-nucleotide entropy, assisting researchers in assessing sequence complexity and variability. The underlying Evo 2 model is trained on over 9 trillion nucleotides from a diverse array of prokaryotic and eukaryotic genomes, employing a deep learning architecture that models biological sequences at single-nucleotide resolution with a context window extending up to 1 million tokens. -
2
Geneious
Geneious
Geneious Prime makes bioinformatics accessible by transforming raw data into visualizations that make sequence analysis intuitive and user-friendly. Simple sequence assembly and easy editing of contigs. Automatic annotation for gene prediction, motifs, translation, and variant calling. Genotype microsatellite traces with automated ladder fitting and peak calling and generates tables of alleles. Beautiful visualizations of annotated genomes and assemblies are displayed in a highly customizable sequence view. Powerful SNP variants analysis, simple RNA-Seq expression analysis, and amplicon metagenomics. Design and test PCR and sequencing primers and create your own searchable primer database. Geneious Biologics is a flexible, scalable, and secure way to streamline your antibody analysis workflows, create high-quality libraries and select the optimal therapeutic candidates.Starting Price: $1,280 per year -
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Correlation Engine
Illumina
Correlation Engine is an interactive omics knowledgebase that puts private omics data in a biological context with highly curated public data. One of the largest biological databases in the world, Correlation Engine provides life science researchers with unprecedented access to vast numbers of high-quality whole-genome analyses and insightful scientific tools. The knowledgebase enables novel discoveries by interrogating billions of data points derived from standardized analyses of whole genome studies. A suite of applications to determine biological context, a continually growing library of curated data sets, and support for multiple species and multi-omic datasets. Utilize a simple graphical user interface to leverage guided workflows, push-button applications, and APIs. Accelerate your journey from omic data to decision and get access to over 25,000 multi-omics studies (from over 250,000 signatures) that have been reanalyzed. -
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HyperProtein
Hypercube
HyperProtein is Hypercube, Inc.'s new product focusing on the computational science associated with protein sequences. The product includes the analysis of one-dimensional protein sequences as well as the analysis of consequent three-dimensional protein structures. In particular, the relationship between sequence and structure is a fundamental facet of the product. Unlike individual software programs that provide capability for some aspect of protein sequence or structure, such as sequence alignment, HyperProtein puts together a multitude of Bioinformatics and Molecular Modeling tools related to the science that initiates with a protein sequence. -
5
Geneyx
Geneyx
Geneyx Analysis is a comprehensive solution for next-generation sequencing (NGS) data that can scale the process of FASTQ to clinical reports for hospital and commercial labs. This advanced platform integrates machine learning and AI-based features to identify novel biomedical insights, while also improving diagnostic yields and turnaround times. By providing a fully transparent and intuitive solution, Geneyx Analysis enables clinicians and researchers to have complete control over data analysis and alleviates the complexities of regulating in-house bioinformatics pipelines. Protocols can be fully customized to accommodate gene panels, exomes, and genomes, and our comprehensive annotation engine supports the analysis of all genetic variants including structural and copy number variations as well as regulatory elements. Together, Geneyx Analysis automates the diagnostic process from sequencer to report, while creating a comprehensive resource for novel variant discovery. -
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Swiss-PdbViewer
Swiss-PdbViewer
Swiss-PdbViewer (aka DeepView) is an application that provides a user-friendly interface allowing to analysis of several proteins at the same time. The proteins can be superimposed in order to deduce structural alignments and compare their active sites or any other relevant parts. Amino acid mutations, H-bonds, angles, and distances between atoms are easy to obtain thanks to the intuitive graphic and menu interface. Swiss-PdbViewer (aka DeepView) has been developed since 1994 by Nicolas Guex. Swiss-PdbViewer was initially tightly linked to SWISS-MODEL, an automated homology modeling server developed within the Swiss Institute of Bioinformatics (SIB) at the Structural Bioinformatics Group at the Biozentrum in Basel. However, the SWISS-MODEL web interface evolved to a point where it is now possible to use it directly for advanced modeling. Maintaining a direct interface with Swiss-PdbViewer is too complex and no longer supported. -
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XetaBase
Zetta Genomics
The unique XetaBase platform simplifies tertiary analysis, aggregating, indexing, and enriching secondary genomic data, enabling continual re-interpretation to unlock research and clinical insight. XetaBase accelerates data management and the cost-effective application of genomic data in the lab and clinic. XetaBase encompasses genomic scale, the greater the volume and complexity, the greater the insight and outcomes. XetaBase is a genomic-native technology, built on the open-source, OpenCB software platform to meet the scale, speed, and re-interpretation demands of genomic medicine. Zetta Genomics delivers genomic data management fit for the precision medicine age. XetaBase is a completely novel solution to the challenges of genomic data. It sweeps away obsolete flat file approaches to bring meaningful and actionable genomic data into the lab and the clinic. XetaBase empowers continual re-interpretation while scaling seamlessly as databases grow to encompass genome sequences. -
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Partek Flow
Partek
Partek bioinformatics software delivers powerful statistical and visualization tools in an easy-to-use interface. Researchers of all skill levels are empowered to explore genomic data quicker and easier than ever before. We turn data into discovery®. Pre-installed workflows and pipelines in our intuitive point-and-click interface make sophisticated NGS and array analysis attainable for any scientist. Custom and public statistical algorithms work in concert to easily and precisely distill NGS data into biological insights. Genome browser, Venn diagrams, heat maps, and other interactive visualizations reveal the biology of your next-generation sequencing and array data in brilliant color. Our Ph.D. scientists are always just a phone call away and ready to help with your NGS analysis any time you have questions. Designed specifically for the compute-intensive needs of next-generation sequencing applications with flexible installation and user management options. -
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QIAGEN CLC Genomics Workbench
QIAGEN Digital Insights
QIAGEN CLC Genomics Workbench is a powerful solution that works for everyone, no matter the workflow. Cutting-edge technology and unique features and algorithms widely used by scientific leaders in industry and academia make it easy to overcome challenges associated with data analysis. User-friendly bioinformatics software solutions allow for comprehensive analysis of your NGS data, including de novo assembly of whole genomes and transcriptomes, resequencing analysis (WGS, WES and targeted panel support), variant calling, RNA-seq, ChIP-seq and DNA methylation (bisulfite sequencing analysis). Analyze your RNA-seq and small RNA (miRNA, lncRNA) data with easy-to-use transcriptomics workflows for differential expression analysis at gene and transcript levels. QIAGEN CLC Genomics Workbench is developed to support a wide range of NGS bioinformatics applications. -
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OmicsBox
BioBam Bioinformatics S.L.
OmicsBox is a leading bioinformatics solution that offers end-to-end data analysis of genomes, transcriptomes, metagenomes, and genetic variation studies. The application is used by top private and public research institutions worldwide and allows researchers to easily process large and complex data sets, and streamline their analysis process. It is designed to be user-friendly, efficient, and with a powerful set of tools to extract biological insights from omics data. The software is structured in different modules, each with a specific set of tools and functions designed to perform different types of analysis, such as de-novo genome assemblies, genetic variation analysis, differential expression analysis, and taxonomic classifications of microbiome data, including the functional interpretation and rich visualizations of results. The functional analysis module includes the popular Blast2GO annotation methodology and makes OmicsBox particularly suited for non-model organism researchStarting Price: €100/month/seat -
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Illumina Connected Analytics
Illumina
Store, archive, manage, and collaborate on multi-omic datasets. Illumina Connected Analytics is a secure genomic data platform to operationalize informatics and drive scientific insights. Easily import, build, and edit workflows with tools like CWL and Nextflow. Leverage DRAGEN bioinformatics pipelines. Organize data in a secure workspace and share it globally in a compliant manner. Keep your data in your cloud environment while using our platform. Visualize and interpret your data with a flexible analysis environment, including JupyterLab Notebooks. Aggregate, query, and analyze sample and population data in a scalable data warehouse. Scale analysis operations by building, validating, automating, and deploying informatics pipelines. Reduce the time required to analyze genomic data, when swift results can be a critical factor. Enable comprehensive profiling to identify novel drug targets and drug response biomarkers. Flow data seamlessly from Illumina sequencing systems. -
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BioTuring Browser
BioTuring Browser
Explore hundreds of curated single-cell transcriptome datasets, along with your own data, through interactive visualizations and analytics. The software also supports multimodal omics, CITE-seq, TCR-seq, and spatial transcriptomic. Interactively explore the world's largest single-cell expression database. Access and query insights from a single-cell database of millions of cells, fully annotated with cell type labels and experimental metadata. Not just creating a gateway to published works, BioTuring Browser is an end-to-end solution for your own single-cell data. Import your fastq files, count matrices, Seurat, or Scanpy objects, and reveal the biological stories inside them. Get a rich package of visualizations and analyses in an intuitive interface, making insight mining from any curated or in-house single-cell dataset become such a breeze. Import single-cell CRISPR screening or Perturb-seq data, and query guide RNA sequences.Starting Price: Free -
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VSClinical
Golden Helix
VSClinical allows for the clinical interpretation of variants based on ACMG & AMP guidelines. The VSClinical guided workflow enables following the American College of Medical Genetics (ACMG) guidelines used to identify and classify causal variants for inherited disease risk, cancer predisposition, and the diagnosis of rare diseases. The ACMG/AMP joint guidelines for variant interpretation provide a set of criteria to score variants and place them into one of five classification tiers. Following the guidelines requires deep diving into the annotations, genomic context, and existing clinical assertions about every variant. VSClinical provides a tailored workflow to score each relevant criterion while also providing all the bioinformatic, literature and evidence from clinical knowledgebases to assist in the scoring and interpretation process. VSClinical is designed to allow variant scientists to efficiently process variants. -
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Profluent
Profluent
Profluent's platform revolutionizes protein design by integrating advanced AI with in-house wet-lab capabilities, enabling the creation of proteins either inspired by nature or reimagined from scratch. This holistic approach allows for precise, adaptable, and scalable solutions to complex biological challenges, delivering results that redefine what's possible with proteins. Profluent's foundation models push the frontier of protein design beyond the limitations of random discovery, facilitating the optimization of multiple attributes simultaneously, accessing greater sequence diversity, and enabling novel functionalities. By extrapolating into new protein spaces, Profluent offers unique possibilities beyond natural or patented proteins, making it cheaper, easier, and feasible for partners to achieve commercial success. Profluent's capabilities are built on a commitment to scientific rigor, leveraging diverse datasets and advanced AI to tackle challenges. -
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Avogadro
Avogadro
Avogadro is an advanced molecule editor and visualizer designed for cross-platform use in computational chemistry, molecular modeling, bioinformatics, materials science, and related areas. It offers flexible high quality rendering and a powerful plugin architecture. Avogadro is a free, open-source molecular editor and visualization tool, designed for use on Mac, Windows, and Linux in computational chemistry, molecular modeling, bioinformatics, materials science, and related areas. It offers flexible high quality rendering and a powerful plugin architecture. -
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Illumina DRAGEN Secondary Analysis
Illumina
The Illumina DRAGEN Secondary Analysis provides accurate, comprehensive, and efficient analysis of next-generation sequencing data. Graph reference genome and machine learning driving unprecedented accuracy. Provides ultra-efficient workflow; can fully process a 34x whole human genome in ~30 minutes with DRAGEN server v4. Furthers ultra-efficient workflow by reducing FASTQ file sizes up to 5×. Analyzes next-generation sequencing (NGS) data from whole genomes, exomes, methylomes, and transcriptomes. Available on platform of choice and scalable based on needs. DRAGEN analysis leads in accuracy for germline and somatic variant calling demonstrated in industry challenges from precisionFDA. DRAGEN analysis enables labs of all sizes and disciplines to do more with their genomic data. DRAGEN analysis uses highly reconfigurable field-programmable gate array technology (FPGA) to provide hardware-accelerated implementations of genomic analysis algorithms. -
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StarDrop
Optibrium
With its comprehensive suite of integrated software, StarDrop™ delivers best-in-class in silico technologies within a highly visual and user-friendly interface. StarDrop™ enables a seamless flow from the latest data through predictive modeling to decision-making regarding the next round of synthesis and research, improving the speed, efficiency, and productivity of the discovery process. Successful compounds require a balance of many different properties. StarDrop™ guides you through this multi-parameter optimization challenge to target compounds with the best chance of success, saving you time and resources by enabling you to synthesize and test fewer compounds. -
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BIOVIA Discovery Studio
Dassault Systèmes
Today’s biopharmaceutical industry is marked by complexity: growing market demands for improved specificity and safety, novel treatment classes and more intricate mechanisms of disease. Keeping up with this complexity requires a deeper understanding of therapeutic behavior. Modeling and simulation methods provide a unique means to explore biological and physicochemical processes down to the atomic level. This can guide physical experimentation, accelerating the discovery and development process. BIOVIA Discovery Studio brings together over 30 years of peer-reviewed research and world-class in silico techniques such as molecular mechanics, free energy calculations, biotherapeutics developability and more into a common environment. It provides researchers with a complete toolset to explore the nuances of protein chemistry and catalyze discovery of small and large molecule therapeutics from Target ID to Lead Optimization. -
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GenomeStudio
Illumina
Visualize and analyze data generated on Illumina array platforms with GenomeStudio Software. This powerful solution supports the genotyping analysis of microarray data. Performance-optimized tools and a user-friendly graphical interface enable you to convert data into meaningful results quickly and easily. Analyze SNP and CNV data across 5 million markers and probes. Detect sample outliers. Analyze differentially expressed genes across different genomes. Profile miRNA expression. Combine mRNA and microRNA data in a single project. Detect cytosine methylation at single-base resolution. Identify methylation signatures across the entire genome. At Illumina, our goal is to apply innovative technologies to the analysis of genetic variation and function, making studies possible that were not even imaginable just a few years ago. It is mission critical for us to deliver innovative, flexible, and scalable solutions to meet the needs of our customers. -
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VarSeq
Golden Helix
Simple, fast, and repeatable variant analysis software for gene panels, exomes, and whole genomes. VarSeq is an intuitive, integrated software solution for tertiary analysis. With VarSeq you can automate your workflows and analyze variants for gene panels, exomes, and whole genomes. Understanding genomic data has never been easier thanks to our software. VarSeq software provides a powerful filtering and annotation engine to sift through large variant data sets. Using a chain of filters, you can quickly narrow your list of variants down to those that are most likely to be of interest. After determining the parameters that work well for your analysis, you can save the state of your filters so that you can easily apply the same analysis to another dataset. The same automated workflow can be used for each batch of samples, making VarSeq an ideal solution for high-throughput environments. Real-time filtering gives you the power to quickly prototype and tune analysis workflows. -
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Eidogen-Sertanty Target Informatics Platform (TIP)
Eidogen-Sertanty
Eidogen-Sertanty's Target Informatics Platform (TIP) is the world's first structural informatics system and knowledgebase that enables researchers with the ability to interrogate the druggable genome from a structural perspective. TIP amplifies the rapidly expanding body of experimental protein structure information and transforms structure-based drug discovery from a low-throughput, data-scarce discipline into a high-throughput, data-rich science. Designed to help bridge the knowledge gap between bioinformatics and cheminformatics, TIP supplies drug discovery researchers with a knowledge base of information that is both distinct from and highly complementary to information furnished by existing bio- and cheminformatics platforms. TIP's seamless integration of structural data management technology with unique target-to-lead calculation and analysis capabilities enhances all stages of the discovery pipeline. -
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Universal Analysis Software (UAS) provides a platform for analyzing and managing forensic genomic data, simplifying complex bioinformatics. The UAS is an all-inclusive solution, containing analysis modules supporting all current ForenSeq workflows including ForenSeq MainstAY, ForenSeq Kintelligence, ForenSeq DNA Signature Prep, ForenSeq mtDNA Whole Genome, and ForenSeq mtDNA Control Region. UAS rapidly generates FASTQ files, performs alignment, and calls forensically relevant variants from NGS data. Extensive testing backs highly reliable variant calls to deliver accurate results in a user-friendly package with no per-seat licenses. Designed specifically for forensic analysts, UAS streamlines handling of base-by-base sequence information and contains a range of features to enable everything from efficient review of everyday STR profiles to detailed analysis of the most challenging samples.
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Congenica
Congenica
We drive precision medicine and help reduce the burden on healthcare systems by delivering automated analysis, diagnosis, and treatment solutions to healthcare providers and patients worldwide. Congenica was founded on pioneering work at the Wellcome Sanger Institute and the UK NHS. Our products combine state-of-the-art technology, market-leading automation, and AI to enable our uniquely differentiated platform to be employed in all areas of human disease where genomic information is key to unlocking actionable insights. We are a digital health company providing software and solutions for the analysis and interpretation of genomic data at scale. Full automation with powerful APIs and ML to reduce the burden on specialist staff, maximize case throughput, accelerate decision-making, and streamline reporting. Certified, accurate, and secure analysis platform to support clinical decisions with the highest degree of confidence in the clinical outcome. -
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Emedgene
Illumina
Emedgene streamlines your tertiary analysis workflows for rare disease genomics and other germline research applications. Emedgene is designed to accelerate the time and certainty in user-defined variant interpretation, prioritization, curation, and research report generation. Enable greater efficiency from your tertiary analysis workflows with explainable AI (XAI) and automation supporting genomes, exomes, virtual panels, and targeted panels. Unify your laboratory and NGS instrumentation with your IT systems to simplify and secure your complete workflow. Confidently keep pace with evolving science, technology, and demand with up-to-date knowledge graph options, curation capabilities, and a team of experts to support your journey. Increase throughput without increasing headcount using explainable AI (XAI) and automated workflows. Implement a high throughput WGS, WES, virtual panel, or targeted panel workflow that is integrated into your lab's digital ecosystem. -
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BaseSpace Sequence Hub
Illumina
Data management and simplified bioinformatics for labs getting started and for rapidly scaling next-generation sequencing (NGS) operations. As a key component of the BaseSpace Suite, BaseSpace Sequence Hub is a direct extension of your Illumina instruments. Encrypted data flow from the instrument into BaseSpace Sequence Hub, enabling you to manage and analyze your data easily with a curated set of analysis apps. BaseSpace Sequence Hub is powered by Amazon Web Services (AWS). Offers a security-first environment. Enables you to set up runs and monitor instrument run quality. Promotes efficiency by converting sequencing data to a standard format and streaming directly to the cloud. Provides access to computing resources without the capital expenditure of in-house infrastructure. Increases organizational productivity with easy access to a multitude of genomic analysis apps (provided by you, Illumina, or third parties). -
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g.nome
Almaden Genomics
g.nome, a cloud-native platform that delivers streamlined, scalable, and interoperable workflows for next-generation sequencing analysis. g.nome provides a low-code/no-code pipeline build. With pre-built workflows and toolkits from a curated library, g.nome is giving power to researchers — enabling them to import custom code, handle big datasets reliably, and optimize team collaboration from anywhere. With g.nome, long-time barriers linked to workflow language, process flow visibility, and quality control are removed. All that’s left are streamlined, scalable, and interoperable genomic workflows — leaving research teams to do what they do best: focus on the science. -
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Genome Analysis Toolkit (GATK)
Broad Institute
Developed in the Data Sciences Platform at the Broad Institute, the toolkit offers a wide variety of tools with a primary focus on variant discovery and genotyping. Its powerful processing engine and high-performance computing features make it capable of taking on projects of any size. The GATK is the industry standard for identifying SNPs and indels in germline DNA and RNAseq data. Its scope is now expanding to include somatic short variant calling and to tackle copy number (CNV) and structural variation (SV). In addition to the variant callers themselves, the GATK also includes many utilities to perform related tasks such as processing and quality control of high-throughput sequencing data and bundles the popular Picard toolkit. These tools were primarily designed to process exomes and whole genomes generated with Illumina sequencing technology, but they can be adapted to handle a variety of other technologies and experimental designs.Starting Price: Free -
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MEGA
MEGA
MEGA (Molecular Evolutionary Genetics Analysis) is a powerful and user-friendly software suite designed for analyzing DNA and protein sequence data from species and populations. It facilitates both automatic and manual sequence alignment, phylogenetic tree inference, and evolutionary hypothesis testing. MEGA supports a variety of statistical methods including maximum likelihood, Bayesian inference, and ordinary least squares, making it an essential tool for comparative sequence analysis and understanding molecular evolution. MEGA offers advanced features such as real-time caption generation to help explain the results and methods used in analysis and the maximum composite likelihood method for estimating evolutionary distances. The software is equipped with robust visual tools like the alignment/trace editor and tree explorer and supports multi-threading for efficient processing. MEGA can be run on multiple operating systems, including Windows, Linux, and macOS.Starting Price: Free -
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SnapGene
SnapGene
Accurately design and simulate cloning procedures. Test complicated projects, catch errors before they happen, and obtain the right constructs the first time. Cloning is easier when you can see what you are doing. The intuitive interface offers you unparalleled visibility into your work, simplifying often complex tasks. SnapGene automates documentation, so you don’t have to. See and share every sequence edit and cloning procedure that led to your final plasmid. Improve your core molecular biology procedures, and improve your results. Master SnapGene and key concepts in cloning with our new online learning center, SnapGene Academy. Containing over 50 video tutorials taught by scientific experts, SnapGene Academy helps you advance your skills across multiple molecular biology courses. SnapGene 7.2 provides a new visualization of primer homodimer structures and enhancements to file management, allowing tabs to be organized in multiple windows using drag and drop.Starting Price: $295 per year -
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Galaxy
Galaxy
Galaxy is an open source, web-based platform for data-intensive biomedical research. If you are new to Galaxy start here or consult our help resources. You can install your own Galaxy by following the tutorial and choosing from thousands of tools from the tool shed. This instance of Galaxy is utilizing infrastructure generously provided by the Texas Advanced Computing Center. Additional resources are provided primarily on the Jetstream2 cloud via ACCESS, and with support from the National Science Foundation. Quantify, visualize, and summarize mismatches in deep sequencing data. Build maximum-likelihood phylogenetic trees. Phylogenomic/evolutionary tree construction from multiple sequences. Merge matching reads into clusters with TN-93. Remove sequences from a reference that are within a given distance of a cluster. Perform maximum-likelihood estimation of gene essentiality scores.Starting Price: Free -
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GenomeBrowse
Golden Helix
This free tool delivers stunning visualizations of your genomic data that give you the power to see what is occurring at each base pair in your samples. GenomeBrowse runs as a native desktop application on your computer. No longer do you have to sacrifice speed and interface quality to obtain a consistent cross-platform experience. It was developed with performance in mind to deliver a faster and more fluid browsing experience than any other genome browser available. GenomeBrowse is also integrated into the powerful Golden Helix VarSeq variant annotation and interpretation platform. If you love the visualization experience of GenomeBrowse, check out VarSeq for filtering, annotating, and analyzing your data before utilizing the same visualization interface. GB can display all your alignment data. Looking at all your samples in one view can help you spot contextually relevant findings.Starting Price: Free -
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Alissa Interpret
Agilent Technologies
Alissa Interpret is your universal genomic data interpretation software for clinical decision support. Increase your productivity, shorten the turnaround time, and maintain regulatory compliance with Alissa Interpret’s agnostic CGH and NGS tertiary analysis platform for variant interpretation and reporting. Achieve complete operational efficiency when pairing Alissa Interpret with Agilent’s fully optimized SureSelect NGS reagents, intuitive secondary NGS analysis Alissa Reporter, Magnis walkaway automation, and TapeStation QC for a streamlined NGS data analysis workflow. External and internal curated variant knowledgebases at your fingertips. Automated variant interpretation solution accelerates CGH and NGS tertiary analysis. One platform for SNVs, InDels, CNVs, LOH, and fusions. Integrate with your LIMS and eliminate genomic data analysis bottlenecks. Connect with peers, share knowledge, and improve diagnostic yield. -
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hc1
hc1
Founded to improve lives with high-value care, hc1 has emerged as the leader in bioinformatics for precision testing and prescribing. The cloud-based hc1 High-Value Care Platform® organizes volumes of live data, including lab results, genomics, and medications, to deliver solutions that ensure that the right patient gets the right test and the right prescription. Today, the hc1 Platform powers solutions that optimize diagnostic testing and prescribing for millions of patients nationally. To learn more about hc1's proven approach to personalizing care while eliminating waste for thousands of health systems, diagnostic laboratories, and health plans, visit www.hc1.com. -
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GeoMx Digital Spatial Profiler (DSP)
nanoString
Quickly resolve tissue heterogeneity and the complexity of microenvironments with the GeoMx Digital Spatial Profiler (DSP), the most flexible and robust spatial multi-omic platform for analysis of FFPE and fresh frozen tissue sections. GeoMx is the only spatial biology platform that non-destructively profiles the expression of RNA and protein from distinct tissue compartments and cell populations with an automated and scalable workflow that integrates with standard histology staining. Spatially profile the whole transcriptome and 570+ protein targets separately or simultaneously from your choice of sample inputs: whole tissue sections, tissue microarrays (TMAs), or organoids. Make GeoMx DSP your spatial biology platform of choice for biomarker discovery and hypothesis testing. Decide where to draw the line and let the tissue be your guide with biology-driven profiling that empowers you to choose the tissue microenvironments and cell types that matter most to you. -
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Loupe Browser
10x Genomics
Loupe Browser is a powerful visualization software that provides the intuitive functionality you need to explore and analyze your 10x Genomics Chromium and Visium data. You can also convert your Seurat objects into Loupe Browser files using the LoupeR package. The navigation and interactive functionality of the Loupe Browser interface uses a lung squamous cell carcinoma dataset. The workspace is centered around the view panel in which single points representing cell barcodes are shown in a variety of projections. Each point represents a single barcode, the vast majority of which correspond to a single cell. The default projection is the t-SNE plot created by the cell ranger pipeline, though other projections are available. You can drag the mouse over the cells to reposition the plot and use the mouse wheel or trackpad to zoom in and out. Cluster labels appear as you move your mouse over the plot, which is useful for data that has a high number of precomputed clusters. -
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Microsoft Genomics
Microsoft
Instead of managing your own data centers, take advantage of Microsoft's scale and experience in running exabyte-scale workloads. Because Microsoft Genomics is on Azure, you have the performance and scalability of a world-class supercomputing center, on demand in the cloud. Take advantage of a backend network with MPI latency under three microseconds and non-blocking 32 gigabits per second (Gbps) throughput. This backend network includes remote direct memory access technology that enables parallel applications to scale to thousands of cores. Azure provides you with high memory and HPC-class CPUs to help you get results fast. Scale up and down based on what you need and pay only for what you use to reduce costs. Tackle data sovereignty requirements with a worldwide network of Azure data centers and adhere to your compliance requirements. Easily integrate into your existing pipeline code using a REST-based API and simple Python client. -
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CZ CELLxGENE Discover
CZ CELLxGENE
Select two custom cell groups based on metadata to find their top differentially expressed genes. Leverage millions of cells from the integrated CZ CELLxGENE corpus for powerful analysis. Execute interactive analyses on a dataset to explore how patterns of gene expression are determined by spatial, environmental, and genetic factors using an interactive speed no-code UI. Understand published datasets or use them as a launchpad to identify new cell sub-types and states. Census provides access to any custom slice of standardized cell data available on CZ CELLxGENE Discover in R and Python. Explore an interactive encyclopedia of 700+ cell types that provides detailed definitions, marker genes, lineage, and relevant datasets in one place. Browse and download hundreds of standardized data collections and 1,000+ datasets characterizing the functionality of healthy mouse and human tissues. -
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Bioconductor
Bioconductor
The Bioconductor project aims to develop and share open source software for precise and repeatable analysis of biological data. We foster an inclusive and collaborative community of developers and data scientists. Resources to maximize the potential of Bioconductor. From basic functionalities to advanced features, our tutorials, guides, and documentation have you covered. Bioconductor uses the R statistical programming language and is open source and open development. It has two releases each year and an active user community. Bioconductor provides Docker images for every release and provides support for Bioconductor use in AnVIL. Founded in 2001, Bioconductor is an open-source software project widely used in bioinformatics and biomedical research. It hosts over 2,000 R packages contributed by over 1,000 developers, with over 40 million downloads per year. Bioconductor has been cited in more than 60,000 scientific publications.Starting Price: Free -
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Cellenics
Biomage
Turn your single-cell RNA sequencing data into meaningful insight with Cellenics software. Biomage hosts a community instance of Cellenics, an open source analytics tool for single-cell RNA sequencing data that has been developed at Harvard Medical School. It enables biologists to explore single-cell datasets without writing code and helps scientists and bioinformaticians to work together more effectively. It takes you from count matrices to publication-ready figures in just a few hours and can be integrated seamlessly with your workflow. It’s fast, interactive, and user-friendly. And it’s cloud-based, secure, and scaleable. The Biomage-hosted community instance of Cellenics is free for academic researchers with small/medium-sized datasets (up to 500,000 cells). It’s used by 3000+ academic researchers studying cancer, cardiovascular health, and developmental biology.Starting Price: Free -
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Parse Biosciences Evercode
Parse Biosciences
Combinatorial barcoding technology strips away the limitations and frustrations of yesterday’s single-cell approach. It ditches the specialized instrument, freeing you to pursue unprecedented discoveries. Unleash the potential of a single cell. Profile from 1000 to 1 million cells or nuclei in a single experiment, offering unparalleled scientific progress. Evercode combinatorial barcoding technology blows droplet-based approaches out of the water. Expand the size of your experiments without the limitations of yesterday’s restraints. Get better data quality. All without the need for finicky hardware that’s already out of date. Perform single-cell experiments with nothing more than a pipette and common laboratory equipment. Split-pool combinatorial barcoding enables scalable single cells without any custom instrument. Scalable single-cell sequencing without the instrument. Each kit provides end-to-end solution reagents and intuitive analysis software. -
41
NVIDIA Clara
NVIDIA
Clara’s domain-specific tools, AI pre-trained models, and accelerated applications are enabling AI breakthroughs in numerous fields, including medical devices, imaging, drug discovery, and genomics. Explore the end-to-end pipeline of medical device development and deployment with the Holoscan platform. Build containerized AI apps with the Holoscan SDK and MONAI, and streamline deployment in next-generation AI devices with the NVIDIA IGX developer kits. The NVIDIA Holoscan SDK includes healthcare-specific acceleration libraries, pre-trained AI models, and reference applications for computational medical devices. -
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SOPHiA GENETICS
SOPHiA GENETICS
Our global data-sharing network generates clinically actionable insights from data to improve patient outcomes worldwide. SOPHiA GENETICS’ mission is to build the future of AI-assisted medicine. We are integrating multimodal healthcare-omics data, unlocking the existing data silos, and developing machine learning models to produce actionable insights that could eventually support healthcare professionals to improve patient outcomes. The revamped interface, new features, and cutting-edge capabilities are set to further accelerate precision medicine workflows, bringing us another step closer to democratizing data-driven medicine. Powered by AI and machine learning (ML), our global cloud-based platform provides a safe, secure, and instantly accessible environment to standardize, compute, and analyze digital health data, generating insights from complex multimodal data sets that have the potential to improve diagnosis, therapy selection, analysis, and drug development. -
43
Promethium
Promethium
Promethium is a GPU-powered chemistry simulation platform designed to accelerate drug and materials development by enabling faster and more accurate quantum chemistry calculations. Built from the ground up for NVIDIA datacenter GPUs like A100, it employs novel QC Ware streaming algorithms to achieve unprecedented computational speed and high throughput-to-power consumption ratios. It supports density functional theory calculations on systems with up to 2,000 atoms, allowing simulations of large molecular systems that are not feasible with legacy CPU-powered ab initio codes. For instance, a single-point calculation of a 2,056-atom protein can be completed in 14 hours on a single GPU. Promethium offers a range of capabilities, including single-point energy calculations, geometry optimization, conformer search, torsion scan, reaction path optimization, transition state optimization, interaction energy computations, and relaxed potential energy surface scans.Starting Price: $30 per hour -
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NVIDIA Parabricks
NVIDIA
NVIDIA® Parabricks® is the only GPU-accelerated suite of genomic analysis applications that delivers fast and accurate analysis of genomes and exomes for sequencing centers, clinical teams, genomics researchers, and high-throughput sequencing instrument developers. NVIDIA Parabricks provides GPU-accelerated versions of tools used every day by computational biologists and bioinformaticians—enabling significantly faster runtimes, workflow scalability, and lower compute costs. From FastQ to Variant Call Format (VCF), NVIDIA Parabricks accelerates runtimes across a series of hardware configurations with NVIDIA A100 Tensor Core GPUs. Genomic researchers can experience acceleration across every step of their analysis workflows, from alignment to sorting to variant calling. When more GPUs are used, a near-linear scaling in compute time is observed compared to CPU-only systems, allowing up to 107X acceleration. -
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Schrödinger
Schrödinger
Transform drug discovery and materials research with advanced molecular modeling. Our physics-based computational platform integrates differentiated solutions for predictive modeling, data analytics, and collaboration to enable rapid exploration of chemical space. Our platform is deployed by industry leaders worldwide for drug discovery, as well as for materials science in fields as diverse as aerospace, energy, semiconductors, and electronics displays. The platform powers our own drug discovery efforts, from target identification to hit discovery to lead optimization. It also drives our research collaborations to develop novel medicines for critical public health needs. With more than 150 Ph.D. scientists on our team, we invest heavily in R&D. We’ve published over 400 peer-reviewed papers that demonstrate the strength of our physics-based approaches, and we’re continually pushing the limits of computer modeling. -
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Kanteron
Kanteron Systems
Kanteron Platform ingested medical images, digital pathology slides, genomics sequences, and patient data from modalities, scanners, sequencers and databases, and provided a complete data toolkit to every team in hospital networks. Pharmacogenomics for adverse medication event prevention, and Precision Medicine application at the point of care: Incorporates sources of drug-gene interaction data that were previously only available in in accessible formats (e.g. tables in a PDF document), implementing the major Pharmacogenomic databases (like PharmGKB, CGI, DGIdb, OpenTargets...) Allows the user to refine their query to certain gene families, types of interactions, classes of drugs, etc. Flexible AI means you can choose the data set that best fits your use case, and apply it to your relevant medical images. -
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Recursion
Recursion
We are a clinical-stage biotechnology company decoding biology by integrating technological innovations across biology, chemistry, automation, machine learning and engineering to industrialize drug discovery. Increased control over biology with tools such as CRISPR genome editing and synthetic biology. Reliable automation of complex laboratory research at an unprecedented scale using advanced robotics. Iterative analysis of, and inference from, large, complex in-house datasets using neural network architectures. Increasing elasticity of high-performance computation using cloud solutions. We are leveraging new technology to create virtuous cycles of learning around datasets to build a next-generation biopharmaceutical company. A synchronized combination of hardware, software and data used to industrialize drug discovery. Reshaping the traditional drug discovery funnel. One of the largest, broadest and deepest pipelines of any technology-enabled drug discovery company. -
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GenomiX
VE3 Global
GenomiX is a unified analytics platform built to manage the complexity of modern genomics research and clinical workflows. It supports large-scale sequencing data, integrates fragmented systems like LIMS and EHRs, and enables multi-omics analysis across DNA, RNA, and epigenetics. With its cloud-agnostic, container-native architecture, GenomiX ensures flexibility, compliance, and scalability for both research and healthcare environments. The platform streamlines workflows with support for popular engines like Nextflow, WDL, and Snakemake, while offering preconfigured bioinformatics pipelines. Advanced AI and ML integrations accelerate clinical interpretation and research insights. GenomiX also prioritizes security, ensuring GDPR, HIPAA, and NHS compliance while facilitating collaboration across institutions. -
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Healthcare Data Analytics
Inspirata
With more than 70% of healthcare data stored in clinical documents, reports, patient chart, clinician notes and discharge letters, our healthcare specific Natural Language Processing and AI Engine identifies the concepts, attributes and context needed to deliver business insights, optimize billing, identify and stratify patient risks, compute quality metrics or collect patient sentiment and outcome data. Leverage difficult-to-surface or entirely untapped data sources to enhance your clinical research or business intelligence. Leverage our database of thousands of clinical concepts such as genomic biomarkers, symptoms, side effects, and medications. Identify disease characteristics, medications, or risk factors from clinical documents to stratify patients and improve the quality of care. Protect the identity of data subjects while maintaining data utility through document de-identification. -
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XIFIN LIS
XIFIN
The award-winning XIFIN LIS is a fully scalable SaaS-based laboratory information system that offers multi-specialty workflows, a comprehensive toolset, flexible and secure connectivity and leading-edge capabilities that optimize high volume and complex testing labs. In response to value-based and patient-centered coordinated care models, the healthcare industry is shifting. Accelerating the shift is the exponential growth in the adoption of genomic testing and personalized medicine using next-generation sequencing (NGS). Laboratories must adapt their existing processes to meet the challenge of implementing and reporting these high complexity tests. Since diagnostic insights have the potential to reduce overall healthcare costs and improve patient care – it is crucial that laboratories better integrate with the healthcare ecosystem. These demands are driving the need for more interaction and greater communication across all healthcare and diagnostic providers.