Best Layer 1 Protocols for Ledger Nano S Plus

Compare the Top Layer 1 Protocols that integrate with Ledger Nano S Plus as of August 2025

This a list of Layer 1 Protocols that integrate with Ledger Nano S Plus. Use the filters on the left to add additional filters for products that have integrations with Ledger Nano S Plus. View the products that work with Ledger Nano S Plus in the table below.

What are Layer 1 Protocols for Ledger Nano S Plus?

Layer 1 protocols, also known as layer 1 blockchains, are blockchain protocols that are built as the base layer of a blockchain. A layer 1 protocol serves as the underlying base blockchain of a blockchain network, as opposed to a layer 2 protocol which is designed to improve the scaling problems and transaction speeds and fees that layer 1 blockchain networks and protocols face. Decentralized applications and cryptocurrencies can be built on Layer 1 protocols, and layer 1 protocols interact with layer 2 protocols in order to improve efficiency and overall user experience. Compare and read user reviews of the best Layer 1 Protocols for Ledger Nano S Plus currently available using the table below. This list is updated regularly.

  • 1
    Bitcoin

    Bitcoin

    Bitcoin

    Bitcoin is an innovative payment network and a new kind of money. Bitcoin uses peer-to-peer technology to operate with no central authority or banks; managing transactions and the issuing of bitcoins is carried out collectively by the network. Bitcoin is open-source; its design is public, nobody owns or controls Bitcoin and everyone can take part. Through many of its unique properties, Bitcoin allows exciting uses that could not be covered by any previous payment system. Bitcoin transactions are secured by mathematics and energy. Cryptographic signatures prevent other people from spending your money. Energy spent by proof of work (PoW) prevents other people from undoing, rearranging or losing your transactions. So long as you take the required steps to protect your wallet, Bitcoin can give you control over your money and a strong level of protection against many types of fraud.
  • 2
    Ripple

    Ripple

    Ripple Labs

    Discover why 200+ financial institutions choose RippleNet to find new customers in new markets, expand services and deliver the best experience in global payments today. Too often, global payments are costly, unreliable and slow. The underlying systems are fragmented and complex. RippleNet offers the most advanced blockchain technology for global payments—making it easy for financial institutions to reach a trusted, growing network of 200+ providers across 40+ countries and 
six continents. Using proven crypto and blockchain technology honed over a decade, Ripple’s enterprise-grade solutions are faster, more transparent, and more cost-effective than traditional financial services. Our customers use these solutions to source crypto, facilitate instant payments, empower their treasury, engage new audiences, lower capital requirements, and drive new revenue.
  • 3
    Ethereum

    Ethereum

    Ethereum Foundation

    Ethereum is the community-run technology powering the cryptocurrency, ether (ETH) and thousands of decentralized applications. Ethereum is a technology that's home to digital money, global payments, and applications. The community has built a booming digital economy, bold new ways for creators to earn online, and so much more. It's open to everyone, wherever you are in the world – all you need is the internet. Today, billions of people can’t open bank accounts, others have their payments blocked. Ethereum's decentralized finance (DeFi) system never sleeps or discriminates. With just an internet connection, you can send, receive, borrow, earn interest, and even stream funds anywhere in the world. Today, we gain access to 'free' internet services by giving up control of our personal data. Ethereum services are open by default – you just need a wallet. Stake your ETH to become an Ethereum validator.
  • 4
    Dogecoin

    Dogecoin

    Dogecoin

    Dogecoin is an open-source peer-to-peer digital currency, favored by Shiba Inus worldwide. You have to sync with the blockchain to use Dogecoin. MultiDoge is a "light" wallet. It syncs with the blockchain by "skimming" through the blockchain, providing fast sync times. Dogecoin Core, on the other hand, is a "full" wallet. It syncs by downloading it, providing a solid-working Dogecoin wallet. Dogecoin sets itself apart from other digital currencies with an amazing, vibrant community made up of friendly folks just like you. "Doge" is our fun, friendly mascot! The Shiba Inu is a Japanese breed of dog that was popularized as an online meme and represents Dogecoin. A Wallet is used for holding your Dogecoins directly on your computer/smartphone. There are numerous amounts of ways to get Dogecoin. You can buy them, trade for them, get tipped, "mine" them, and more. They are surprisingly endless!
  • 5
    XRP Ledger (XRPL)
    The XRP Ledger: The Blockchain Built for Business. The XRP Ledger (XRPL) is a decentralized, public blockchain led by a global community of businesses and developers looking to solve problems and create value. Proven reliable over more than a decade of error-free functioning, the XRPL offers streamlined development, low transaction costs, high performance, and sustainability. So you can build with confidence–and move your most critical projects forward. The XRP Ledger is a decentralized public blockchain built for business. The peer-to-peer network that manages the ledger is open to everyone. The XRP Ledger is maintained by software engineers, server operators, users, and businesses–a global community working to solve problems and create real-world value.
  • 6
    Solana

    Solana

    Solana Foundation

    Solana is a fast, secure, and censorship resistant blockchain providing the open infrastructure required for global adoption. The best projects in DeFi, Web3, and blockchain gaming choose to build on Solana for the long-term. Solana can process 50k transactions per second. Don't believe us? Stress test the network to experience Solana's speed for yourself. Say goodbye to high fees and slow confirmations. Solana is built for speed, without trade-offs. Solana leverages Proof of History and several other breakthrough innovations to allow the network to scale at the rate of Moore's Law. Never worry about rising fees as your user base grows. Solana is designed to keep fees low for applications with billions of users. Solana's single global state ensures composability between projects. Never deal with multiple shards or layer 2 systems.
  • 7
    Cardano

    Cardano

    Cardano

    Cardano is a blockchain platform for changemakers, innovators, and visionaries, with the tools and technologies required to create possibility for the many, as well as the few, and bring about positive global change. Cardano is a proof-of-stake blockchain platform: the first to be founded on peer-reviewed research and developed through evidence-based methods. It combines pioneering technologies to provide unparalleled security and sustainability to decentralized applications, systems, and societies. With a leading team of engineers, Cardano exists to redistribute power from unaccountable structures to the margins – to individuals – and be an enabling force for positive change and progress. Cardano restores trust to global systems – creating, through science, a more secure, transparent, and sustainable foundation for individuals to transact and exchange, systems to govern, and enterprises to grow.
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