Compare the Top Free e-Prescribing Software as of March 2026

What is Free e-Prescribing Software?

e-Prescribing software provides physicians and medical professionals with a platform to generate and send electronic prescription orders to pharmacies and their clients. Compare and read user reviews of the best Free e-Prescribing software currently available using the table below. This list is updated regularly.

  • 1
    Perfect E-Prescription System
    The Perfect E-Prescription System is a sophisticated software solution designed to enhance the efficiency and safety of the prescription process in healthcare settings. By enabling healthcare providers to electronically send prescriptions directly to pharmacies, it reduces the risk of errors and ensures that patients receive their medications promptly. The system includes features for managing medication histories, checking drug interactions, and accurately dosing, which altogether streamline the prescription lifecycle. Additional functionalities include the ability to manage and authorize prescription refills, which aids in chronic disease management, and real-time tracking of prescription status, which keeps both providers and patients informed. Integration with Perfect Pharmacy Manager ensures seamless workflow between prescribing and dispensing medications, thereby optimizing operational efficiency and improving patient outcomes.
    Starting Price: $5/month
  • 2
    eMedicalPractice

    eMedicalPractice

    eMedicalPractice

    eMedPractice is a cloud-based software system designed to streamline healthcare management functions. Our comprehensive solution begins with the seamless integration of our robust Electronic Health Records (EHR), Practice Management (PM) and Revenue Cycle Management (RCM) modules into one unified platform. This powerful combination of features is just the beginning. We offer a full suite of solutions and services to help you practice with efficiency and optimize workflows. Whether you're a small practice or a large healthcare organization, eMedPractice can help you save time, reduce costs, and enhance patient care. With our clinician-first software, you can manage patient data, automate administrative tasks, and improve revenue generation.
    Starting Price: $199.00/month
  • 3
    ScriptSure

    ScriptSure

    DAW Systems, Inc.

    Discover the pinnacle of E-Prescribing solutions with ScriptSure Cloud ERX – the unparalleled winner of the esteemed White Coat Award for Most Accurate Prescriptions in 2021, 2022, and 2023, securing its position as an 11-time recipient of this prestigious accolade. ScriptSure Cloud ERX seamlessly integrates full e-prescribing capabilities, EPCS (controlled substance prescribing) and weekly updates to medications and daily updates to pharmacy lists. With ScriptSure you get price transparency as well; detailed costs, alternatives and ePA requirement indicators for most medications. Enjoy a user-friendly interface and streamlined workflow methods for electronic refills, order sets, compound medication ordering, prescription printing, patient reports and comprehensive audit logs. Security and compliance are paramount, with ScriptSure being fully HIPAA compliant, ensuring the confidentiality and privacy of patient data. ScriptSure is fast, accurate and built for patient safety.
  • 4
    Veradigm ePrescribe
    Veradigm ePrescribe is a comprehensive, easy-to-use solution for electronic prescribing, designed to ensure you and your patients are covered every step of the way. Whether you are looking for low-cost e-prescribing to save you time and free you from your script pad forever, or advanced e-prescribing with all the latest features that keep you up to date with regulatory mandates, Veradigm ePrescribe is the proven choice used by over 140,000 prescribers for hundreds of millions of transactions every year. Save time by prescribing electronically within your clinical workflow. Drive improvements in medication adherence, satisfaction, and efficiency. e-prescribe from anywhere you have internet access, including your mobile device. Far beyond streamlining prescribing and helping you eliminate calls and faxes, Veradigm ePrescribe delivers patients’ medication histories and formularies, automatic interaction checks, and the advanced e-prescribing capabilities you need.
    Starting Price: $59 per month
  • 5
    Practice Mate

    Practice Mate

    Office Ally

    Practice Mate by Office Ally is a comprehensive practice management solution used by over 25,000 healthcare organizations. It simplifies revenue cycle management and assists in HIPAA-compliant recordkeeping for new and existing practices. Its user-friendly interface offers easy billing management that checks eligibility and benefits and manages claim submission and tracking. Its seamless integration with other Office Ally solutions provides additional functionality such as patient intake, reminders, e-prescriptions, and more. With no cost, commitment, or implementation, you can get started today to help reduce unnecessary administrative tasks, enhance provider job satisfaction, and improve the overall patient experience.
    Starting Price: $0
  • 6
    Wellevate

    Wellevate

    Wellevate and Emerson Ecologics

    Dispense supplements to your patients' doors, taking a margin or not. Grow your practice and make wellness accessible. We are focused on delivering the brands, resources & services to help support integrative health practitioners provide the best possible care to their patients. We're poised to offer practitioners and their patients a simpler path to lifelong wellness, reaching more people with an unmatched experience and catalog. Industry-leading virtual treatment plan tool helps you build your most comprehensive recommendations ever. Create your account, upload your certifications, and deliver simple, complete care. Make evidence-informed decisions with protocols, condition catalog search, and the ingredient library. Boost adherence with 150+ resources that you can easily attach to your treatment plans. Work from the software you already use with access to 20+ HIPAA compliant EHRs and more.
    Starting Price: Free
  • 7
    pMD

    pMD

    pMD

    End-to-end practice management and revenue cycle solutions. From patient intake to getting paid, pMD has all the software and services you need to run your medical practice. With fewer systems involved, there's less room for errors and inefficiencies. Use all of the features pMD has to offer, or we can integrate seamlessly with your existing systems. A comprehensive and secure communication strategy means fewer gaps in care and a better patient experience. Delivering the best possible care means having a standardized communication channel to connect about and with your patients. We make sure all the important patient information is accessible in one place, saving you valuable time when you need to access it. pMD offers the comprehensive, integrated, and HIPAA-compliant telemedicine platform solution health care providers need to provide unparalleled patient care. Explore all the easy-to-use telehealth software app offers and get pMD telemedicine for your practice and patients.
    Starting Price: Free
  • 8
    Osmind

    Osmind

    Osmind

    Osmind simplifies mental health treatment workflows and improves the patient experience. Our platform is an all-in-one solution that saves you time and maximizes your impact, all at an affordable price. Stop wasting time on a complex EHR that requires endless clicks and extensive workflows. Osmind was built by psychiatrists with mental health practices in mind. The Osmind EHR is ready for the breakthrough mental health treatments of tomorrow. Easily manage medications, and administer interventions like TMS, ketamine, SPRAVATO®, or psychedelic medicine. Provide a modern patient experience that improves patient engagement and satisfaction. Your patients will have access to an easy-to-use mobile app to track their progress, securely communicate, and submit out-of-network claims. Run your practice your way with flexible scheduling, virtual visits, and payments all in one place. Reduce your overhead and improve cashflow, so you can get back to focusing on your patients.
    Starting Price: Free
  • 9
    DocVilla
    DocVilla is a comprehensive, multi-specialty, mobile-friendly, HIPAA-compliant cloud-based health technology platform that integrates EHR/EMR, telehealth, e-prescribing, patient engagement, medical billing, analytics and reporting, direct primary care, inventory management, remote patient monitoring, and more into a unified, configurable suite. Providers simply sign in to access a customizable electronic medical records system with secure messaging, video visits, controlled-substance e-Rx, and a free patient portal for scheduling, payment, and secure communications. The platform streamlines workflows by automating eligibility checks, claim submissions, charge posting, insurance eligibility and claim filing, ERAs/EOBs, medical dictation and speech-to-text, patient consent forms, lab integrations, electronic fax, and automatic appointment reminders.
    Starting Price: $100 per month
  • 10
    ViSolve OpenEMR Pro
    ViSolve specializes in providing cloud hosting services through AWS to healthcare organizations with low-cost ways to deliver their websites and web applications securely. We are one of the leading contributors of OpenEMR and has a team of expert professionals at customizing OpenEMR to allow your practice to get the most benefit from it. ViSolve is specialized in providing Health Information Exchange (HIE) through interoperability FHIR/Mirth.It includes seamless data exchange between disparate systems. The electronic medical records software that lets you chart your way in, because one-size doesn't fit all! It's a highly personal way to create optimal workflows that lets you consult more patients in an environment that fits your style. By Offering customisable solution, OpenEMR Pro is helping to fulfill vision of truly connected office, in which patients, providers and technology are connected seamlessly and exchange data with other hospitals, when required, through Mirth Connect.
    Starting Price: $99 per month
  • 11
    Treat

    Treat

    DoseSpot

    Treat 4 advances e-prescribing to a new level of power and convenience. Experience Treat on any device with a refined mobile experience. Discover new features like Real-Time Prescription Benefits and Eligibility. Send prescriptions from your desktop or mobile device with Treat 4, giving you the power and flexibility to care for your patients, wherever they may be. It’s never been easier to send and manage electronic prescriptions. Treat 4 offers a robust set of e‑prescribing features to accelerate your workflow. All accessible from your favorite device. Treat 4’s intuitive workflow makes electronic prescribing an asset instead of a distraction. A streamlined design is informed by a sharpened focus on efficiency when writing prescriptions. Your most frequently prescribed medications can be saved as favorites, accessible when and where you need them. Treat 4 is accessible from any web browser as a standalone e‑prescribing app.
  • 12
    DENmaar Guardian
    The DENmaar Guardian will allow you to check on the status and explore many features. The DENmaar Guardian offers a suite of services designed to improve and provide measurable financial results. From insurance credentialing and billing to our advanced automated RCM, our behavioral and mental health providers can be assured of optimal economic outcomes. Patient scheduling is critical for operational efficiency, reducing missed visits, and ensuring that patients are seen promptly. The DENmaar scheduler offers several key features that you should look for when analyzing the quality of a patient scheduling system. Stay HIPAA compliant while collecting payment using DENpay. Practitioners must keep their patient's medical, financial, and personal information safely secured.  Patients continue to carry an increased burden of deductibles, premiums, and other medical expenses. Advanced yet user-friendly medical EHR software specifically designed for behavioral healthcare.
    Starting Price: Free
  • 13
    iCare

    iCare

    iCare.com

    Finally, an Electronic Health Record system for hospitals, clinics, and practices that is flexible enough to change as healthcare evolves yet doesn’t cost a fortune to implement and operate. Delivered in the cloud, the iCare Enterprise Cloud EHR is a fully integrated system which includes a full range of administrative, clinical and revenue cycle management capabilities. iCare provides a complete solution for clinical, billing and administrative functionality at a fraction of the cost of legacy software. A web-based user interface not only gives your users access to iCare from any device but it also allows the workflows to be configured to the way clinicians work. Legacy EHR systems are built on outdated client-server systems that are costly, closed, inflexible and slow to innovate. iCare is built with the future in mind. The industry’s most modern architecture, intuitive user interfaces, and rock solid performance – no other EHR comes close to iCare.
  • 14
    Practice Fusion

    Practice Fusion

    Practice Fusion

    Save time with templates and patient charts in the cloud-based EHR that adapt to your needs. Browse from a library of medical charting templates built by practices like yours. Efficiently manage prescriptions including controlled substances and those requiring prior authorization. Seamlessly exchange information with local pharmacies, laboratories, imaging centers and other tools integrated into the EHR platform. Choose from over 500 lab and imaging centers to order tests and share results with patient. Flexible billing options with industry-leading partners who help you get paid faster. Monitor your progress with insightful dashboards and submit reporting data to CMS directly through your EHR. Access customizable dashboards to track your progress on quality initiatives like MIPS. Explore extensive education and training materials to navigate the complexities of quality measures.
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