Compare the Top AI Agent Builders that integrate with Python as of December 2025 - Page 2

This a list of AI Agent Builders that integrate with Python. Use the filters on the left to add additional filters for products that have integrations with Python. View the products that work with Python in the table below.

  • 1
    AgentKit

    AgentKit

    OpenAI

    AgentKit is a unified suite of tools designed to streamline the process of building, deploying, and optimizing AI agents. It introduces Agent Builder, a visual canvas that lets developers compose multi-agent workflows via drag-and-drop nodes, set guardrails, preview runs, and version workflows. The Connector Registry centralizes the management of data and tool integrations across workspaces and ensures governance and access control. ChatKit enables frictionless embedding of agentic chat interfaces, customizable to match branding and experience, into web or app environments. To support robust performance and reliability, AgentKit enhances its evaluation infrastructure with datasets, trace grading, automated prompt optimization, and support for third-party models. It also supports reinforcement fine-tuning to push agent capabilities further.
    Starting Price: Free
  • 2
    Kodey

    Kodey

    Kodey

    Kodey is a comprehensive AI-agent platform that lets users build, deploy, and manage autonomous AI agents without needing to write code. It offers a visual agent builder for non-technical users, enabling you to drag and drop components and connect workflows or data sources in minutes, plus full-support SDKs and APIs (e.g., Python, JavaScript, REST/GraphQL) for developers who want deeper customization. Once configured, agents run in secure, containerized environments and can be deployed to production via REST, WebSocket, or as embeddable web components; Kodey.ai automatically scales infrastructure to meet demand. It includes prebuilt integrations (databases, third-party tools, etc.), real-time monitoring and analytics, version control, and collaboration tools with role-based access control, all ensuring reliability, security, and maintainability in production workflows.
    Starting Price: $100 per month
  • 3
    Dasha

    Dasha

    Dasha

    Dasha is a conversational AI-as-a-service platform that lets you embed realistic voice and text conversational capabilities into your apps or products. With a single integration, create smart conversational apps for web, desktop, mobile, IoT, and call centers. DashaScript is an event-driven declarative programming language used to design complex real-world conversations that pass a limited Turing test. Automate call center conversations, recreate the Google Duplex demo in under 400 lines of code or create a no-code GUI for your users that translates into DashaScript code. If it is connected to the internet and has access to a speaker/mic, it can run a Dasha application. Your conversational voice/chat apps use your existing infrastructure, including databases, external services (Airtable, Zendesk, TalkDesk, etc.), and business logic. Run conversations through anything. Feed your custom data into Dasha and consume results where they provide the most value.
  • 4
    AI Crypto-Kit
    AI Crypto-Kit empowers developers to build crypto agents by seamlessly integrating leading Web3 platforms like Coinbase, OpenSea, and more to automate real-world crypto/DeFi workflows. Developers can build AI-powered crypto automation in minutes, including applications such as trading agents, community reward systems, Coinbase wallet management, portfolio tracking, market analysis, and yield farming. The platform offers capabilities engineered for crypto agents, including fully managed agent authentication with support for OAuth, API keys, JWT, and automatic token refresh; optimization for LLM function calling to ensure enterprise-grade reliability; support for over 20 agentic frameworks like Pippin, LangChain, and LlamaIndex; integration with more than 30 Web3 platforms, including Binance, Aave, OpenSea, and Chainlink; and SDKs and APIs for agentic app interactions, available in Python and TypeScript.
  • 5
    Orq.ai

    Orq.ai

    Orq.ai

    Orq.ai is the #1 platform for software teams to operate agentic AI systems at scale. Optimize prompts, deploy use cases, and monitor performance, no blind spots, no vibe checks. Experiment with prompts and LLM configurations before moving to production. Evaluate agentic AI systems in offline environments. Roll out GenAI features to specific user groups with guardrails, data privacy safeguards, and advanced RAG pipelines. Visualize all events triggered by agents for fast debugging. Get granular control on cost, latency, and performance. Connect to your favorite AI models, or bring your own. Speed up your workflow with out-of-the-box components built for agentic AI systems. Manage core stages of the LLM app lifecycle in one central platform. Self-hosted or hybrid deployment with SOC 2 and GDPR compliance for enterprise security.
  • 6
    Dify

    Dify

    Dify

    Dify is an open-source platform designed to streamline the development and operation of generative AI applications. It offers a comprehensive suite of tools, including an intuitive orchestration studio for visual workflow design, a Prompt IDE for prompt testing and refinement, and enterprise-level LLMOps capabilities for monitoring and optimizing large language models. Dify supports integration with various LLMs, such as OpenAI's GPT series and open-source models like Llama, providing flexibility for developers to select models that best fit their needs. Additionally, its Backend-as-a-Service (BaaS) features enable seamless incorporation of AI functionalities into existing enterprise systems, facilitating the creation of AI-powered chatbots, document summarization tools, and virtual assistants.
  • 7
    PromptQL

    PromptQL

    Hasura

    PromptQL is an enterprise-grade AI platform that builds reasoning models with near-perfect accuracy, tailored to each organization’s unique context. Unlike generic AI tools, PromptQL learns your business rules, tacit knowledge, and internal language to act like a trusted analyst or engineer. It empowers companies to deploy specialized AI that not only delivers correct answers but also signals confidence levels and learns continuously from feedback. Within 14 days, enterprises can go from setup to real-world rollout, unlocking measurable results faster than traditional AI deployments. Used by Fortune 100 companies and global enterprises, PromptQL consistently outperforms warehouse-native AI solutions in accuracy and reliability. Designed for adoption, not obsolescence, PromptQL enables organizations to build AI that truly understands their business.
  • 8
    Smolagents

    Smolagents

    Smolagents

    Smolagents is an AI agent framework developed to simplify the creation and deployment of intelligent agents with minimal code. It supports code-first agents where agents execute Python code snippets to perform tasks, offering enhanced efficiency compared to traditional JSON-based approaches. Smolagents integrates with large language models like those from Hugging Face, OpenAI, and others, enabling developers to create agents that can control workflows, call functions, and interact with external systems. The framework is designed to be user-friendly, requiring only a few lines of code to define and execute agents. It features secure execution environments, such as sandboxed spaces, for safe code running. Smolagents also promotes collaboration by integrating deeply with the Hugging Face Hub, allowing users to share and import tools. It supports a variety of use cases, from simple tasks to multi-agent workflows, offering flexibility and performance improvements.
  • 9
    Dendrite

    Dendrite

    Dendrite

    Dendrite is a framework-agnostic platform that empowers developers to create web-based tools for AI agents, enabling them to authenticate, interact with, and extract data from any website. By simulating human-like browsing behavior, Dendrite facilitates seamless web navigation and data retrieval for AI applications. The platform offers a Python SDK, providing developers with the necessary tools to build AI agents capable of performing tasks such as interacting with web elements and extracting information. Dendrite's flexibility allows it to integrate with any tech stack, making it a versatile solution for developers aiming to enhance their AI agents' web interaction capabilities. Your Dendrite client syncs with website authentication sessions in your local browser, no need to share or store login credentials. Use our Chrome Extension, Dendrite Vault, to securely share authentication sessions from your browser with the Dendrite client.
  • 10
    Amazon Nova Act
    ​Amazon Nova Act is an AI model designed to perform actions within web browsers, enabling the development of agents capable of completing tasks such as submitting out-of-office requests, scheduling calendar events, and setting up 'away from office' emails. Unlike traditional large language models that primarily generate natural language responses, Nova Act focuses on executing tasks in digital environments. The Nova Act SDK allows developers to decompose complex workflows into reliable atomic commands (e.g., search, checkout, answer questions about the screen) and incorporate detailed instructions where necessary. It also supports API calls and direct browser manipulation through Playwright to enhance reliability. Developers can integrate Python code, including tests, breakpoints, asserts, or thread pools for parallelization, to manage web page load times effectively.
  • 11
    Scottie

    Scottie

    Scottie

    Describe what you need in plain English. Scottie turns it into a working agent you can run on our cloud or export to your own hosting service. Join our waitlist today to secure your spot and get exclusive early access to premium features. Everything you need to build, test, and deploy AI agents in minutes. Pick from today's leading language models and switch anytime without rebuilding (OpenAI, Gemini, Anthropic, Llama, and more). Bring your company knowledge together from Slack, Google Drive, Notion, Confluence, GitHub, and more. Your data stays private and secure. Scottie supports models from all top vendors. Switch models anytime without rebuilding your agents. Scottie agents adapt to different roles and industries, operating exactly how you need them to. The AI tutor analyzes student responses, provides personalized feedback, and adapts difficulty based on performance.
  • 12
    Upsonic

    Upsonic

    Upsonic

    Upsonic is an open source framework that simplifies AI agent development for business needs. It enables developers to build, manage, and deploy agents with integrated Model Context Protocol (MCP) tools across cloud and local environments. Upsonic reduces engineering effort by 60-70% with built-in reliability features and service client architecture. It offers a client-server architecture that isolates agent applications, keeping existing systems healthy and stateless. It provides more reliable agents, scalability, and a task-oriented structure needed for completing real-world cases. Upsonic supports autonomous agent characterization, allowing self-defined goals and backgrounds, and integrates computer-use capabilities for executing human-like tasks. With direct LLM call support, developers can access models without abstraction layers, completing agent tasks faster and more cost-effectively.
  • 13
    Airweave

    Airweave

    Airweave

    Airweave is an open source platform that transforms application data into agent-ready knowledge, enabling AI agents to semantically search across various apps, databases, and document stores. It simplifies the process of building intelligent agents by offering no-code solutions, instant data synchronization, and scalable deployment options. Users can connect their data sources using OAuth2, API keys, or database credentials, initiate data synchronization with minimal configuration, and provide agents with a unified search endpoint to access the necessary information. Airweave supports over 100 connectors, including integrations with Google Drive, Slack, Notion, Jira, GitHub, and Salesforce, allowing agents to access a wide range of data sources. It handles the entire data pipeline, from authentication and extraction to embedding and serving, automating tasks such as data ingestion, enrichment, mapping, and syncing to vector stores and graph databases.
  • 14
    String.com

    String.com

    Pipedream

    String is the first text-to-agent platform by Pipedream that lets you prompt, run, edit, and deploy AI agents in seconds, no drag-and-drop canvases, just natural language commands that generate production-ready code. Backed by Pipedream’s five years of experience building thousands of app integrations and Internet-scale agent infrastructure, String connects to over 2,700 APIs and embeds 10,000+ tools with managed authentication, so your agents can solve ten times more use cases than typical no-code builders. The intuitive web interface guides you through creating agents that monitor GitHub issues and automate ticket creation, schedule meetings, analyze data, send Slack messages, post to social media, update databases, and much more, all with full audit trails, customizable queues, and built-in data stores. Real-time dashboards display agent performance, logs, and metrics, while built-in security and privacy controls (SOC 2 Type II, ISO 27001, HIPAA, GDPR) ensure safe operation.
  • 15
    Sim Studio

    Sim Studio

    Sim Studio

    Sim Studio is a powerful, AI-native platform for designing, testing, and deploying agentic workflows through an intuitive, Figma-like visual editor that eliminates boilerplate code and infrastructure overhead. Developers can immediately start building multi-agent applications with full control over system prompts, tool definitions, sampling parameters, and structured output formatting, while maintaining the flexibility to switch seamlessly among OpenAI, Anthropic, Claude, Llama, Gemini, and other LLM providers without refactoring. The platform supports full local development via Ollama integration for privacy and cost efficiency during prototyping, then enables scalable cloud deployment when you’re ready. Sim Studio connects your agents to existing tools and data sources in seconds, importing knowledge bases automatically and offering over 40 pre-built integrations.
  • 16
    Naptha

    Naptha

    Naptha

    Naptha is a modular AI platform for autonomous agents that empowers developers and researchers to build, deploy, and scale cooperative multi‑agent systems on the agentic web. Its core innovations include Agent Diversity, which continuously upgrades performance by orchestrating diverse models, tools, and architectures; Horizontal Scaling, which supports collaborative networks of millions of AI agents; Self‑Evolved AI, where agents learn and optimize themselves beyond human‑designed capabilities; and AI Agent Economies, which enable autonomous agents to generate useful goods and services. Naptha integrates seamlessly with popular frameworks and infrastructure, LangChain, AgentOps, CrewAI, IPFS, NVIDIA stacks, and more, via a Python SDK that upgrades existing agent frameworks with next‑generation enhancements. Developers can extend or publish reusable components on the Naptha Hub, run full agent stacks anywhere a container can execute on Naptha Nodes.
  • 17
    Agent Builder
    Agent Builder is part of OpenAI’s tooling for constructing agentic applications, systems that use large language models to perform multi-step tasks autonomously, with governance, tool integration, memory, orchestration, and observability baked in. The platform offers a composable set of primitives—models, tools, memory/state, guardrails, and workflow orchestration- that developers assemble into agents capable of deciding when to call a tool, when to act, and when to halt and hand off control. OpenAI provides a new Responses API that combines chat capabilities with built-in tool use, along with an Agents SDK (Python, JS/TS) that abstracts the control loop, supports guardrail enforcement (validations on inputs/outputs), handoffs between agents, session management, and tracing of agent executions. Agents can be augmented with built-in tools like web search, file search, or computer use, or custom function-calling tools.