Nemo Files

N E M O v2.4.0 [02 June 2025]

Package update: 14 July 2025

This is a beta/pre-release version still under testing. Thanks for reporting
issues to https://groups.google.com/g/nemo-simul.

We have made major changes in the quantitative trait and overall performances.

The quantitative trait has been enhanced with options to modify the degree of
pleiotropy among loci. Now, quantitative loci can vary in their pleiotropic
degree from no pleiotropy (affect one trait) to full pleiotropy (affect all
traits). The mutation matrix can thus be locus-specific.

The multi-linear model of epistasis for quantitative trait loci has also been
added, allowing for non-linear genotype-phenotype mapping of the quantitative
traits. Epistasis does not vary with pleiotropy (no epistatic pleiotropy).

A new LCE is introduced: "phenotype_expression". It models phenotypic plasticity
of the quantitative trait with a linear reaction norm. The LCE is linked to
the quantitative trait. Multiple quantiative traits can by plastic with evolving
norms of reaction (intercept and slope can evolve).

Recombination of multiple traits on the same genetic map hase been revised and
optimized, which reduces run time for large maps (large number of genetic
elements on the same map).

We added more options for and optimized reproduction in Wright-Fisher populations.

Many bugs have been fixed by revising large parts of the code.