Browse Code
BigBang/Horizon is a proteomics data analysis pipeline with focus on the shotgun LC/MSMS workflow.
Features
- State-of-the-art proteomics data analysis (LC/MSMS)
- Graphical user interface (easy to use)
- Independent data processing modules (windows services)
- Independently archivable projects
- All data is kept in database, no need to look for your files in various places
- Experiment design support: organize samples into biological samples and repeats
- .RAW file import
- Data preprocessing prior to database search
- Batch mascot submission
- Combination of search results for downstream analysis
- Peptide-level FDR analysis with flexible mixture model (Choi et al, 2008)
- Protein identification
- Protein posterior probability calculation using Bayesian methods (Serang et al, 2010)
- TMT/iTRAQ quantitation (isotope error correction with a non-negative least squares method)
- Exports to text file (csv, tsv) and Excel
- Queuing system for data processing tasks
License
MIT LicenseFollow BigBangHorizon
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