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#276 protein interactions should be shown for both genes involved

open
nobody
5
2006-02-15
2006-02-15
Anonymous
No

Annotations with "protein-protein physical
interaction" only show up on the subject term detail
page, but should be displayed on the object term
detail page as well.

This would allow a curator to see the interaction
from either gene page, and edit it accordingly.

For example, the gene CBL2 has an interaction with
CIPK1 (http://tesuque.stanford.edu:8080/pub/Display?
acc=term:95151)
But, if you went to the CIPK1 gene page, you would
not know about this interaction, as it is not shown.
(http://tesuque.stanford.edu:8080/pub/Display?
acc=gene:28951)

If other cases exist where the annotation object term
is also a gene term, the annotation should be
displayed on both pages.

Discussion

  • Brandon Zoeckler

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    brandon submitted

     
  • Tanya Berardini

    Tanya Berardini - 2006-08-03

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    user_id=579762

    What is the best way to solve the problem? We want to show
    the interaction in both directions so if we annotate

    gene A has protein-protein interaction with gene B

    then the reverse annotation of

    gene B has protein-protein interaction with gene A

    should also be true.

    Should this be solved at the level of display or should we
    store the data as a separate row in the db? If the latter,
    can we make this second entry appear automatically?

    How about making the GO 'protein binding' annotation
    automatically from any A has protein-protein physical
    interaction with B annotation? This would also cut down on
    curation time quite a bit.

     
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