Browse free open source Python AI Agents and projects below. Use the toggles on the left to filter open source Python AI Agents by OS, license, language, programming language, and project status.

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  • 1
    AutoGPT

    AutoGPT

    Powerful tool that lets you create and run intelligent agents

    AutoGPT is an experimental open-source application showcasing the capabilities of the GPT-4 language model. This program, driven by GPT-4, chains together LLM "thoughts", to autonomously achieve whatever goal you set. As one of the first examples of GPT-4 running fully autonomously, AutoGPT pushes the boundaries of what is possible with AI.
    Downloads: 23 This Week
    Last Update:
    See Project
  • 2
    ChemCrow

    ChemCrow

    Chemcrow

    ChemCrow is an AI-powered framework designed to assist in chemical research and discovery. It integrates AI models with chemical knowledge bases to provide intelligent recommendations for synthesis planning, reaction prediction, and material discovery. This tool helps automate and accelerate research in computational chemistry and drug development.
    Downloads: 15 This Week
    Last Update:
    See Project
  • 3
    Agent Zero

    Agent Zero

    Agent Zero AI framework

    Agent Zero is not a predefined agentic framework. It is designed to be dynamic, organically growing, and learning as you use it. Agent Zero is fully transparent, readable, comprehensible, customizable and interactive. Agent Zero uses the computer as a tool to accomplish its (your) tasks. Agents can communicate with their superiors and subordinates, asking questions, giving instructions, and providing guidance. Instruct your agents in the system prompt on how to communicate effectively. The terminal interface is real-time streamed and interactive. You can stop and intervene at any point. If you see your agent heading in the wrong direction, just stop and tell it right away. There is a lot of freedom in this framework. You can instruct your agents to regularly report back to superiors asking for permission to continue. You can instruct them to use point-scoring systems when deciding when to delegate subtasks. Superiors can double-check subordinates' results and disputes.
    Downloads: 12 This Week
    Last Update:
    See Project
  • 4
    Agent S2

    Agent S2

    Agent S: an open agentic framework that uses computers like a human

    Simular's Agent S2 represents a leap forward in the development of computer-use agents, capable of autonomously interacting with a range of devices and interfaces. By integrating specialized AI models, Agent S2 delivers state-of-the-art performance, whether on desktop systems or smartphones. Through modular architecture, it efficiently handles complex tasks, such as navigating UIs, performing low-level actions like text selection, and executing high-level strategies like planning. Additionally, the system's proactive hierarchical planning allows for real-time adaptation, making it an ideal solution for businesses seeking to streamline operations and automate digital workflows. Agent S2 is designed with flexibility, enabling seamless scaling for future applications and tasks.
    Downloads: 9 This Week
    Last Update:
    See Project
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  • 5
    CrewAI

    CrewAI

    Framework for orchestrating role-playing, autonomous AI agents

    Framework for orchestrating role-playing, autonomous AI agents. By fostering collaborative intelligence, CrewAI empowers agents to work together seamlessly, tackling complex tasks. The power of AI collaboration has too much to offer. CrewAI is designed to enable AI agents to assume roles, share goals, and operate in a cohesive unit - much like a well-oiled crew. Whether you're building a smart assistant platform, an automated customer service ensemble, or a multi-agent research team, CrewAI provides the backbone for sophisticated multi-agent interactions.
    Downloads: 8 This Week
    Last Update:
    See Project
  • 6
    Atomic Agents

    Atomic Agents

    Building AI agents, atomically

    The Atomic Agents framework is designed around the concept of atomicity to be an extremely lightweight and modular framework for building Agentic AI pipelines and applications without sacrificing developer experience and maintainability. The framework provides a set of tools and agents that can be combined to create powerful applications. It is built on top of Instructor and leverages the power of Pydantic for data and schema validation and serialization. All logic and control flows are written in Python, enabling developers to apply familiar best practices and workflows from traditional software development without compromising flexibility or clarity.
    Downloads: 6 This Week
    Last Update:
    See Project
  • 7
    GPTme

    GPTme

    Your agent in your terminal, equipped with local tools

    GPTMe is a personal AI chatbot designed for self-reflection, journaling, and productivity, using GPT models to generate personalized insights and responses.
    Downloads: 6 This Week
    Last Update:
    See Project
  • 8
    LangGraph

    LangGraph

    Build resilient language agents as graphs

    LangGraph is a library for building stateful, multi-actor applications with LLMs, used to create agent and multi-agent workflows. Compared to other LLM frameworks, it offers these core benefits: cycles, controllability, and persistence. LangGraph allows you to define flows that involve cycles, essential for most agentic architectures, differentiating it from DAG-based solutions. As a very low-level framework, it provides fine-grained control over both the flow and state of your application, crucial for creating reliable agents. Additionally, LangGraph includes built-in persistence, enabling advanced human-in-the-loop and memory features.
    Downloads: 6 This Week
    Last Update:
    See Project
  • 9
    TapeAgents

    TapeAgents

    A framework that facilitates all stages of LLM development

    TapeAgents is a framework that facilitates all stages of the Large Language Model (LLM) agent development lifecycle, providing tools for building, testing, and deploying AI agents.
    Downloads: 6 This Week
    Last Update:
    See Project
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  • 10
    c/ua

    c/ua

    c/ua is the Docker Container for Computer-Use AI Agents

    Cua is a Docker-based framework that facilitates the deployment and management of computer-use AI agents. It provides a sandboxed environment where agents can perform tasks on macOS and Linux virtual machines, supporting various AI models and ensuring safe execution. Cua is particularly useful for developers looking to test and run AI agents in controlled settings.
    Downloads: 6 This Week
    Last Update:
    See Project
  • 11
    BISHENG

    BISHENG

    BISHENG is an open LLM devops platform for next generation apps

    BISHENG is an open LLM application DevOps platform, focusing on enterprise scenarios. It has been used by a large number of industry-leading organizations and Fortune 500 companies. "Bi Sheng" was the inventor of movable type printing, which played a vital role in promoting the transmission of human knowledge. We hope that BISHENG can also provide strong support for the widespread implementation of intelligent applications. Everyone is welcome to participate.
    Downloads: 5 This Week
    Last Update:
    See Project
  • 12
    OpenAI Python

    OpenAI Python

    The official Python library for the OpenAI API

    The OpenAI Python library provides convenient access to the OpenAI REST API from any Python 3.7+ application. The library includes type definitions for all request params and response fields, and offers both synchronous and asynchronous clients powered by httpx.
    Downloads: 5 This Week
    Last Update:
    See Project
  • 13
    Browser Use

    Browser Use

    Make websites accessible for AI agents

    Browser-Use is a framework that makes websites accessible for AI agents, enabling automated interactions and data extraction from web pages.
    Downloads: 4 This Week
    Last Update:
    See Project
  • 14
    Griptape

    Griptape

    Python framework for AI workflows and pipelines with chain of thought

    The Griptape framework provides developers with the ability to create AI systems that operate across two dimensions: predictability and creativity. For predictability, Griptape enforces structures like sequential pipelines, DAG-based workflows, and long-term memory. To facilitate creativity, Griptape safely prompts LLMs with tools (keeping output data off prompt by using short-term memory), which connects them to external APIs and data stores. The framework allows developers to transition between those two dimensions effortlessly based on their use case. Griptape not only helps developers harness the potential of LLMs but also enforces trust boundaries, schema validation, and tool activity-level permissions. By doing so, Griptape maximizes LLMs’ reasoning while adhering to strict policies regarding their capabilities.
    Downloads: 4 This Week
    Last Update:
    See Project
  • 15
    OpenHands

    OpenHands

    Open-source autonomous AI software engineer

    Welcome to OpenHands (formerly OpenDevin), an open-source autonomous AI software engineer who is capable of executing complex engineering tasks and collaborating actively with users on software development projects. Use AI to tackle the toil in your backlog, so you can focus on what matters: hard problems, creative challenges, and over-engineering your dotfiles We believe agentic technology is too important to be controlled by a few corporations. So we're building all our agents in the open on GitHub, under the MIT license. Our agents can do anything a human developer can: they write code, run commands, and use the web. We're partnering with AI safety experts like Invariant Labs to balance innovation with security.
    Downloads: 4 This Week
    Last Update:
    See Project
  • 16
    uAgents

    uAgents

    A fast and lightweight framework for creating decentralized agents

    uAgents is a library developed by Fetch.ai that allows for creating autonomous AI agents in Python. With simple and expressive decorators, you can have an agent that performs various tasks on a schedule or takes action on various events.
    Downloads: 4 This Week
    Last Update:
    See Project
  • 17
    DB-GPT

    DB-GPT

    Revolutionizing Database Interactions with Private LLM Technology

    DB-GPT is an experimental open-source project that uses localized GPT large models to interact with your data and environment. With this solution, you can be assured that there is no risk of data leakage, and your data is 100% private and secure.
    Downloads: 3 This Week
    Last Update:
    See Project
  • 18
    DSPy

    DSPy

    DSPy: The framework for programming—not prompting—language models

    Developed by the Stanford NLP Group, DSPy (Declarative Self-improving Python) is a framework that enables developers to program language models through compositional Python code rather than relying solely on prompt engineering. It facilitates the construction of modular AI systems and provides algorithms for optimizing prompts and weights, enhancing the quality and reliability of language model outputs.
    Downloads: 3 This Week
    Last Update:
    See Project
  • 19
    Langroid

    Langroid

    Harness LLMs with Multi-Agent Programming

    Given the remarkable abilities of recent Large Language Models (LLMs), there is an unprecedented opportunity to build intelligent applications powered by this transformative technology. The top question for any enterprise is: how best to harness the power of LLMs for complex applications? For technical and practical reasons, building LLM-powered applications is not as simple as throwing a task at an LLM system and expecting it to do it. Effectively leveraging LLMs at scale requires a principled programming framework. In particular, there is often a need to maintain multiple LLM conversations, each instructed in different ways, and "responsible" for different aspects of a task.
    Downloads: 3 This Week
    Last Update:
    See Project
  • 20
    PraisonAI

    PraisonAI

    PraisonAI application combines AutoGen and CrewAI or similar framework

    PraisonAI application combines AutoGen and CrewAI or similar frameworks into a low-code solution for building and managing multi-agent LLM systems, focusing on simplicity, customization, and efficient human-agent collaboration. Chat with your ENTIRE Codebase. Praison AI, leveraging both AutoGen and CrewAI or any other agent framework, represents a low-code, centralized framework designed to simplify the creation and orchestration of multi-agent systems for various LLM applications, emphasizing ease of use, customization, and human-agent interaction.
    Downloads: 3 This Week
    Last Update:
    See Project
  • 21
    Self-Operating Computer

    Self-Operating Computer

    A framework to enable multimodal models to operate a computer

    The Self-Operating Computer Framework is an innovative system that enables multimodal models to autonomously operate a computer by interpreting the screen and executing mouse and keyboard actions to achieve specified objectives. This framework is compatible with various multimodal models and currently integrates with GPT-4o, o1, Gemini Pro Vision, Claude 3, and LLaVa. Notably, it was the first known project to implement a multimodal model capable of viewing and controlling a computer screen. The framework supports features like Optical Character Recognition (OCR) and Set-of-Mark (SoM) prompting to enhance visual grounding capabilities. It is designed to be compatible with macOS, Windows, and Linux (with X server installed), and is released under the MIT license.
    Downloads: 3 This Week
    Last Update:
    See Project
  • 22
    cognee

    cognee

    Deterministic LLMs Outputs for AI Applications and AI Agents

    We build for developers who need a reliable, production-ready data layer for AI applications. Cognee implements scalable, modular data pipelines that allow for creating the LLM-enriched data layer using graph and vector stores. Cognee acts a semantic memory layer, unveiling hidden connections within your data and infusing it with your company's language and principles. This self-optimizing process ensures ultra-relevant, personalized, and contextually aware LLM retrievals. Any kind of data works; unstructured text or raw media files, PDFs, tables, presentations, JSON files, and so many more. Add small or large files, or many files at once. We map out a knowledge graph from all the facts and relationships we extract from your data. Then, we establish graph topology and connect related knowledge clusters, enabling the LLM to "understand" the data.
    Downloads: 3 This Week
    Last Update:
    See Project
  • 23
    mcp-use

    mcp-use

    A solution to build and deploy MCP agents and applications

    mcp-use is an open source development platform offering SDKs, cloud infrastructure, and a developer-friendly control plane for building, managing, and deploying AI agents that leverage the Model Context Protocol (MCP). It enables connection to multiple MCP servers, each exposing specific tool capabilities like browsing, file operations, or specialized integrations, through a unified MCPClient. Developers can create custom agents (via MCPAgent) that dynamically select the most appropriate server for each task using configurable pipelines or a built-in server manager. It simplifies authentication, access control, audit logging, observability, sandboxed runtime environments, and deployment workflows, whether self-hosted or managed, making MCP development production-ready. With integrations for popular frameworks like LangChain (Python) and LangChain.js (TypeScript), mcp-use accelerates the creation of tool-enabled AI agents.
    Downloads: 3 This Week
    Last Update:
    See Project
  • 24
    smolagents

    smolagents

    Agents write python code to call tools and orchestrate other agents

    This library is the simplest framework out there to build powerful agents. We provide our definition in this page, where you’ll also find tips for when to use them or not (spoilers: you’ll often be better off without agents). smolagents is a lightweight framework for building AI agents using large language models (LLMs). It simplifies the development of AI-driven applications by providing tools to create, train, and deploy language model-based agents.
    Downloads: 3 This Week
    Last Update:
    See Project
  • 25
    AgentForge

    AgentForge

    Extensible AGI Framework

    AgentForge is a framework for creating and deploying AI agents that can perform autonomous decision-making and task execution. It enables developers to define agent behaviors, train models, and integrate AI-powered automation into various applications.
    Downloads: 2 This Week
    Last Update:
    See Project
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