Python Agentic AI Tools

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Browse free open source Python Agentic AI Tools and projects below. Use the toggles on the left to filter open source Python Agentic AI Tools by OS, license, language, programming language, and project status.

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  • 1
    Qwen-Agent

    Qwen-Agent

    Agent framework and applications built upon Qwen>=3.0

    Qwen-Agent is a framework for building applications / agents using Qwen models (version 3.0+). It provides components for instruction following, tool usage (function calling), planning, memory, RAG (retrieval augmented generation), code interpreter, etc. It ships with example applications (Browser Assistant, Code Interpreter, Custom Assistant), supports GUI front-ends, backends, server setups. Agent workflow can maintain context / memory to perform multi-turn or more complex logic over time. It acts as the backend for Qwen Chat among other use cases. Built-in Code Interpreter tool that can execute code (locally) as part of agent workflows.
    Downloads: 9 This Week
    Last Update:
    See Project
  • 2
    Agentic Security

    Agentic Security

    Agentic LLM Vulnerability Scanner / AI red teaming kit

    The open-source Agentic LLM Vulnerability Scanner.
    Downloads: 6 This Week
    Last Update:
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  • 3
    MetaGPT

    MetaGPT

    The Multi-Agent Framework

    The Multi-Agent Framework: Given one line Requirement, return PRD, Design, Tasks, Repo. Assign different roles to GPTs to form a collaborative software entity for complex tasks. MetaGPT takes a one-line requirement as input and outputs user stories / competitive analysis/requirements/data structures / APIs / documents, etc. Internally, MetaGPT includes product managers/architects/project managers/engineers. It provides the entire process of a software company along with carefully orchestrated SOPs.
    Downloads: 6 This Week
    Last Update:
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  • 4
    OpenAI Agents (Python)

    OpenAI Agents (Python)

    A lightweight, powerful framework for multi-agent workflows

    openai-agents-python is a library developed by OpenAI to simplify the process of creating and running agents that interact with tools and APIs using OpenAI models. It provides abstractions for tool usage, memory management, and agent workflows, enabling developers to define function-calling agents that reason through multi-step tasks. Ideal for building custom AI workflows, the library supports dynamic tool definitions and contextual memory handling.
    Downloads: 6 This Week
    Last Update:
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  • 5
    OpenAI Agents SDK

    OpenAI Agents SDK

    A lightweight, powerful framework for multi-agent workflows

    The OpenAI Agents Python SDK is a powerful yet lightweight framework for developing multi-agent workflows. This framework enables developers to create and manage agents that can coordinate tasks autonomously, using a set of instructions, tools, guardrails, and handoffs. The SDK allows users to configure workflows in which agents can pass control to other agents as necessary, ensuring dynamic task management. It also includes a built-in tracing system for tracking, debugging, and optimizing agent activities.
    Downloads: 6 This Week
    Last Update:
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  • 6
    AutoGPT

    AutoGPT

    Powerful tool that lets you create and run intelligent agents

    AutoGPT is an experimental open-source application showcasing the capabilities of the GPT-4 language model. This program, driven by GPT-4, chains together LLM "thoughts", to autonomously achieve whatever goal you set. As one of the first examples of GPT-4 running fully autonomously, AutoGPT pushes the boundaries of what is possible with AI.
    Downloads: 5 This Week
    Last Update:
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  • 7
    ChemCrow

    ChemCrow

    Chemcrow

    ChemCrow is an AI-powered framework designed to assist in chemical research and discovery. It integrates AI models with chemical knowledge bases to provide intelligent recommendations for synthesis planning, reaction prediction, and material discovery. This tool helps automate and accelerate research in computational chemistry and drug development.
    Downloads: 5 This Week
    Last Update:
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  • 8
    OpenAI Python

    OpenAI Python

    The official Python library for the OpenAI API

    The OpenAI Python library provides convenient access to the OpenAI REST API from any Python 3.7+ application. The library includes type definitions for all request params and response fields, and offers both synchronous and asynchronous clients powered by httpx.
    Downloads: 5 This Week
    Last Update:
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  • 9
    Browser Use

    Browser Use

    Make websites accessible for AI agents

    Browser-Use is a framework that makes websites accessible for AI agents, enabling automated interactions and data extraction from web pages.
    Downloads: 4 This Week
    Last Update:
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  • 10
    GPTme

    GPTme

    Your agent in your terminal, equipped with local tools

    GPTMe is a personal AI chatbot designed for self-reflection, journaling, and productivity, using GPT models to generate personalized insights and responses.
    Downloads: 3 This Week
    Last Update:
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  • 11
    LangGraph

    LangGraph

    Build resilient language agents as graphs

    LangGraph is a library for building stateful, multi-actor applications with LLMs, used to create agent and multi-agent workflows. Compared to other LLM frameworks, it offers these core benefits: cycles, controllability, and persistence. LangGraph allows you to define flows that involve cycles, essential for most agentic architectures, differentiating it from DAG-based solutions. As a very low-level framework, it provides fine-grained control over both the flow and state of your application, crucial for creating reliable agents. Additionally, LangGraph includes built-in persistence, enabling advanced human-in-the-loop and memory features.
    Downloads: 3 This Week
    Last Update:
    See Project
  • 12
    OpenHands

    OpenHands

    Open-source autonomous AI software engineer

    Welcome to OpenHands (formerly OpenDevin), an open-source autonomous AI software engineer who is capable of executing complex engineering tasks and collaborating actively with users on software development projects. Use AI to tackle the toil in your backlog, so you can focus on what matters: hard problems, creative challenges, and over-engineering your dotfiles We believe agentic technology is too important to be controlled by a few corporations. So we're building all our agents in the open on GitHub, under the MIT license. Our agents can do anything a human developer can: they write code, run commands, and use the web. We're partnering with AI safety experts like Invariant Labs to balance innovation with security.
    Downloads: 3 This Week
    Last Update:
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  • 13
    Self-Operating Computer

    Self-Operating Computer

    A framework to enable multimodal models to operate a computer

    The Self-Operating Computer Framework is an innovative system that enables multimodal models to autonomously operate a computer by interpreting the screen and executing mouse and keyboard actions to achieve specified objectives. This framework is compatible with various multimodal models and currently integrates with GPT-4o, o1, Gemini Pro Vision, Claude 3, and LLaVa. Notably, it was the first known project to implement a multimodal model capable of viewing and controlling a computer screen. The framework supports features like Optical Character Recognition (OCR) and Set-of-Mark (SoM) prompting to enhance visual grounding capabilities. It is designed to be compatible with macOS, Windows, and Linux (with X server installed), and is released under the MIT license.
    Downloads: 3 This Week
    Last Update:
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  • 14
    Agent Zero

    Agent Zero

    Agent Zero AI framework

    Agent Zero is not a predefined agentic framework. It is designed to be dynamic, organically growing, and learning as you use it. Agent Zero is fully transparent, readable, comprehensible, customizable and interactive. Agent Zero uses the computer as a tool to accomplish its (your) tasks. Agents can communicate with their superiors and subordinates, asking questions, giving instructions, and providing guidance. Instruct your agents in the system prompt on how to communicate effectively. The terminal interface is real-time streamed and interactive. You can stop and intervene at any point. If you see your agent heading in the wrong direction, just stop and tell it right away. There is a lot of freedom in this framework. You can instruct your agents to regularly report back to superiors asking for permission to continue. You can instruct them to use point-scoring systems when deciding when to delegate subtasks. Superiors can double-check subordinates' results and disputes.
    Downloads: 2 This Week
    Last Update:
    See Project
  • 15
    CrewAI

    CrewAI

    Framework for orchestrating role-playing, autonomous AI agents

    Framework for orchestrating role-playing, autonomous AI agents. By fostering collaborative intelligence, CrewAI empowers agents to work together seamlessly, tackling complex tasks. The power of AI collaboration has too much to offer. CrewAI is designed to enable AI agents to assume roles, share goals, and operate in a cohesive unit - much like a well-oiled crew. Whether you're building a smart assistant platform, an automated customer service ensemble, or a multi-agent research team, CrewAI provides the backbone for sophisticated multi-agent interactions.
    Downloads: 2 This Week
    Last Update:
    See Project
  • 16
    GPT Researcher

    GPT Researcher

    LLM based autonomous agent that does online comprehensive research

    Say Hello to GPT Researcher, your AI agent for rapid insights and comprehensive research. GPT Researcher is the leading autonomous agent that takes care of everything from accurate source gathering to organization of research results.
    Downloads: 2 This Week
    Last Update:
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  • 17
    MindsDB

    MindsDB

    Making Enterprise Data Intelligent and Responsive for AI

    MindsDB is an AI data solution that enables humans, AI, agents, and applications to query data in natural language and SQL, and get highly accurate answers across disparate data sources and types. MindsDB connects to diverse data sources and applications, and unifies petabyte-scale structured and unstructured data. Powered by an industry-first cognitive engine that can operate anywhere (on-prem, VPC, serverless), it empowers both humans and AI with highly informed decision-making capabilities. A federated query engine that tidies up your data-sprawl chaos while meticulously answering every single question you throw at it. MindsDB has an MCP server built in that enables your MCP applications to connect, unify and respond to questions over large-scale federated data—spanning databases, data warehouses, and SaaS applications.
    Downloads: 2 This Week
    Last Update:
    See Project
  • 18
    Portia SDK Python

    Portia SDK Python

    Portia Labs Python SDK for building agentic workflows

    portia‑sdk‑python is an open-source Python SDK by Portia Labs for creating reliable, stateful, authenticated multi-agent AI workflows. It supports tool-backed agents capable of real-world interactions—like web browsing, API access, and human-in-the-loop clarifications—while maintaining transparency and auditability through structured plans and execution hooks. Designed for production environments, the SDK integrates with local or cloud LLMs (e.g. OpenAI, Anthropic, Mistral, Gemini) and supports extensive tool registries, session handling, and memory management.
    Downloads: 2 This Week
    Last Update:
    See Project
  • 19
    Quark Agent

    Quark Agent

    Quark Agent - Your AI-powered Android APK Analyst

    With Quark Agent, you can perform analyses using only natural language. It creates Quark Script code following your ideas and adjusts the code promptly as you provide feedback.
    Downloads: 2 This Week
    Last Update:
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  • 20
    Skyvern

    Skyvern

    Automate browser-based workflows with LLMs and Computer Vision

    Skyvern uses a combination of computer vision and AI to understand content on a webpage, making it adaptable to any website. Skyvern takes instructions in natural language, allowing it to execute complex objectives with simple commands. Skyvern is an API-first product. Workflows execute in the cloud, allowing it to run hundreds of workflows at the same time. Skyvern's AI decisions come with built-in explanations, providing clear summaries and justifications for every action. Support for proxies, with support for country, state, or even precise zip-code level targeting. Skyvern understands how to solve CAPTCHAs to complete complicated workflows. Support for authenticating into user accounts, including support for 2FA/TOTP. Extract data from workflows in any schema of your choice including CSV or JSON. Automate procurement pipelines, breeze through government forms, and complete workflows in any language.
    Downloads: 2 This Week
    Last Update:
    See Project
  • 21
    Agno

    Agno

    Lightweight framework for building Agents with memory, knowledge, etc.

    Agno is a modular, open-source artificial general intelligence (AGI) research platform that allows developers to build, evaluate, and experiment with cognitive architectures in a composable way. It provides a flexible framework for modeling reasoning, memory, decision-making, and planning, aimed at long-term AI research beyond narrow learning. Agno embraces multi-agent environments and symbolic reasoning as part of its core design, enabling experiments with structured knowledge, goal-oriented behaviors, and meta-learning. It’s designed for researchers seeking an extensible platform to explore AGI components without being tied to black-box models.
    Downloads: 1 This Week
    Last Update:
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  • 22
    DB-GPT

    DB-GPT

    Revolutionizing Database Interactions with Private LLM Technology

    DB-GPT is an experimental open-source project that uses localized GPT large models to interact with your data and environment. With this solution, you can be assured that there is no risk of data leakage, and your data is 100% private and secure.
    Downloads: 1 This Week
    Last Update:
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  • 23
    Dragonfire

    Dragonfire

    The open-source virtual assistant for Ubuntu based Linux distributions

    Dragonfire is the open-source virtual assistant project for Ubuntu-based Linux distributions. Her main objective is to serve as a command and control interface to the helmet user. So that you will be able to give orders just by using your voice commands and your eye movements. That makes the helmet handsfree. We are planning to ship Dragonfire as a preinstalled software package on DragonOS Linux Distribution. DragonOS will be a Linux distribution specially designed for the helmet. It will contain various software packages for controlling the helmet. It will be the first of its kind. Dragonfire uses Mozilla DeepSpeech to understand your voice commands and Festival Speech Synthesis System to handle text-to-speech tasks.
    Downloads: 1 This Week
    Last Update:
    See Project
  • 24
    Haystack

    Haystack

    Haystack is an open source NLP framework to interact with your data

    Apply the latest NLP technology to your own data with the use of Haystack's pipeline architecture. Implement production-ready semantic search, question answering, summarization and document ranking for a wide range of NLP applications. Evaluate components and fine-tune models. Ask questions in natural language and find granular answers in your documents using the latest QA models with the help of Haystack pipelines. Perform semantic search and retrieve ranked documents according to meaning, not just keywords! Make use of and compare the latest pre-trained transformer-based languages models like OpenAI’s GPT-3, BERT, RoBERTa, DPR, and more. Pick any Transformer model from Hugging Face's Model Hub, experiment, find the one that works. Use Haystack NLP components on top of Elasticsearch, OpenSearch, or plain SQL. Boost search performance with Pinecone, Milvus, FAISS, or Weaviate vector databases, and dense passage retrieval.
    Downloads: 1 This Week
    Last Update:
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  • 25
    Klavis AI

    Klavis AI

    Open Source MCP integration for AI applications

    Klavis AI is an open-source platform that simplifies the integration of Model Context Protocols (MCPs) into AI applications. It provides hosted, secure MCP servers with built-in OAuth support, eliminating the need for complex authentication management and client-side code. Klavis AI enables developers to connect AI agents to various tools and services efficiently, facilitating scalable and secure AI deployments.
    Downloads: 1 This Week
    Last Update:
    See Project
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