Showing 39 open source projects for "mer"

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  • 1
    UniversalMer

    UniversalMer

    A CLI k-mer counting tool for multiple sizes of k at once.

    UniversalMer is a k-mer counting tool for multiple size of k at once. It is available for DNA, RNA, and protein sequences. The program counts and summarizes the exact frequency of all k-mers from 1-mer to a user-defined maximum length (kmax). Analyzing the k-mer spectrum across multiple values of k can be done in seconds. This program is designed for bioinformatics researchers and scientists.
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  • 2

    UniversalMer2

    A CLI k-mer counting tool for multiple size of k at once.

    UniversalMer is a k-mer counting tool for multiple size of k at once. It is available for DNA, RNA, and protein sequences. The program counts and summarizes the exact frequency of all k-mers from 1-mer to a user-defined maximum length (kmax). This kmax can be specified as any length or can be automatically determined by the longest repeated patterns found in the input sequence.
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  • 3

    PLEK

    predictor of long non-coding RNAs and mRNAs based on k-mer scheme

    INSTALLATION Pre-requisite: 1. Linux 2. C/C++ compiler (i.e. gcc, g++) 3. Python 2.5.0 or later versions (http://www.python.org/) Steps: 1. Download PLEK.1.2.tar.gz from https://sourceforge.net/projects/plek/files/ and decompress it. $ tar zvxf PLEK.1.2.tar.gz 2. Compile PLEK. $ cd PLEK.1.2 $ python PLEK_setup.py USAGE python PLEK.py -fasta fasta_file -out output_file -thread number_of_threads -minlength min_length_of_sequence -isoutmsg 0_or_1...
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    Downloads: 3 This Week
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  • 4

    FCGRGen

    A tool for generating Frequency Chaos Game Representation images

    FCGRGen is a user-friendly tool for generating Frequency Chaos Game Representation (FCGR) images of genomic sequences. It takes input genomic sequences in FASTA file format and provides an easy-to-use interface for specifying the value of k (the length of oligonucleotides) and generating FCGR images. • Input genomic sequences in FASTA file format. • Browse button for selecting the input file. • Browse button for selecting the output folder. • Specify the value of k for FCGR generation. •...
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    kSNP

    kSNP4 does SNP discovery and SNP annotation from whole genomes

    kSNP4 identifies the pan-genome SNPs in a set of genome sequences, and estimates phylogenetic trees based upon those SNPs. SNP discovery is based on k-mer analysis, and requires no multiple sequence alignment or the selection of a reference genome, so kSNP4 can take 100's of microbial genomes as input. A SNP locus is defined by an oligo of length k surrounding a central SNP allele. kSNP4 can analyze both complete (finished) genomes and unfinished genomes in assembled contigs or raw, unassembled reads. ...
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    Downloads: 33 This Week
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  • 6
    PWMScan

    PWMScan

    A Web-based genome-wide Position Weight Matrix (PWM) Scanner

    ...The PWM is the most commonly used mathematical model to describe the DNA binding specificity of a transcription factor (TF). A PWM contains scores for each base at each position of the binding site. The TF binding score for a given k-mer sequence is then obtained by simply adding up the base-specific scores at respective positions of the binding site. PWMScan takes as input a PWM, the background probabilities for the letters of the DNA alphabet, and a threshold score or a p-value. The search is carried out across the entire genome sequence. It can accept PWMs, such as those available in the Transfac or Jaspar databases as well as plain-text PWMs. ...
    Downloads: 2 This Week
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  • 7
    Meraculous-2D

    Meraculous-2D

    Eukaryotic Genome Assembler

    ---------------------------------------- IMPORTANT: Meraculous-2D has been superseded by the HipMer assembler, available here: https://sourceforge.net/projects/hipmer/ ----------------------------------------- Meraculous-2D is a whole genome assembler for NGS reads (Illumina) that is capable of assembling large, diploid genomes with modest computational requirements. Features include: - Efficient k-mer counting and deBruijn graph traversal - Two modes of handling of diploid allelic variation - Improved scaffolding that produces more complete assemblies without compromising scaffolding accuracy. The assembly is driven by a perl pipeline which performs data fragmentation and load balancing, as well as submission and monitoring of multiple task arrays on a GE/SLURM-type cluster or a standalone multi-core server. ...
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  • 8

    bbgs_ng1

    Bayerns beste Gipfelstürmer

    ...Für eine "professionelle" Softwarelösung reicht das nicht aus. Dabei ist grade in diesem Bereich eine starke individuelle Anpassung wichtig. Was bleibt also? Bauen mer selber! Wer sich für das Projekt interessiert oder dieses sogar Unterstützen möchte findet hier alle Infos: http://bayerns-beste-gipfelstuermer.de/
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  • 9
    EDCC-CNG

    EDCC-CNG

    Exploration and categorization of CREs and CRMs

    ...CNG provides an unbiased neural network approach to assess the importance of positional features that were determined by EDCC. To sustain a high computational performance even for large datasets, the mostly in Python 3 written programs use k-mer based indexing, parallelization and a neural network approach for categorization. For further information please refer to the publication: doi.org/10.1371/journal.pone.0190421
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  • 10
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  • 11
    CoSA (Concurrent Subtractive assembly) is a package to detect differential short sequencing reads by comparing two groups of metagenomes on the basis of kmer frequencies. KMC 2 is one of the fastest k-mer counting implementations, so we employ KMC 2 for k-mer counting in our package. Because in many cases we need to compare tens of or even hundreds of samples, we adopt the concurrent hash table in Libcuckoo for efficient k-mer counting. Once the differential reads are extracted, they can be used for downstream analysis including assembly to identify genes that are differentially abundant between groups of metagenomes (e.g., healthy vs diseased). ...
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  • 12

    hakmer

    Parses genome sequences into k-mers for phylogeny reconstruction

    This code is a homology-aware phylogenomics tool for rapidly parsing whole genome sequences and building sets of small multiple sequence alignments for tree construction. The code relies on a new implementation of suffix arrays to store and retrieve orthologous k-mers across several genomes. Resulting k-mer blocks can then be combined into one or more supermatrices for further phylogenetic analysis.
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  • 13

    PB-sQF_BacterialTyping

    Bacterial Typing from either assembled or raw short reads file

    Probability Binning - signature Quadratic Form, PB-sQF, types unknown sequence to one of the 628 bacterial library genomes which gives the smallest test statistics thus most similar library strain. The input file is the k-mer counts of the unknown assembled genome sequence or raw short reads file in decimal format generated by KAnalyze developed by P. Audano et al. (https://sourceforge.net/projects/kanalyze/). The download included the library index, the library name and sample unknowns.
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  • 14
    Suite of tools for DNA sequence analysis - searching (EST, mRNA, sequencer reads); aligning (ESTs, mRNA, whole genome); and analysis (repeats, kmers).
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  • 15
    KAnalyze

    KAnalyze

    DNA/RNA Sequence K-mer Toolkit

    KAnalyze is a Java toolkit designed to convert DNA and RNA sequences into k-mers. It is both a command line application and an API.
    Downloads: 1 This Week
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  • 16
    SparseAssembler: Sparse k-mer Graph for Memory Efficient Genome Assembly
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  • 17

    COPEread

    Connecting Overlapped Pair-End Reads

    COPE (Connecting Overlapped Pair-End reads) is a method to align and connect the illumina sequenced Pair-End reads of which the insert size is smaller than the sum of the two read length.The connected reads can be used in genome assembly, resequencing and transcriptome research. The full citation: COPE: An accurate k-mer based pair-end reads connection tool to facilitate genome assembly Binghang Liu; Jianying Yuan; Siu-Ming Yiu; Zhenyu Li; Yinlong Xie; Yanxiang Chen; Yujian Shi; Hao Zhang; Yingrui Li; Tak-Wah Lam; Ruibang Luo Bioinformatics (2012) 28(22): 2870-2874; doi: 10.1093/bioinformatics/bts563
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  • 18
    Subtractive Assembly

    Subtractive Assembly

    An approach for comparative metagenomics by assembling the differences

    ...Given two metagenomic datasets A and B, subtractive assembly approach first identifies reads that are likely sampled from abundant or unique genomes in A (or B vice versa), using Bloom-filter based k-mer counting. And one can assemble only these reads separately using metagenomic assemblers such as IDBA-UD. We further developed concurrent subtractive assembly (CoSA), which is an improved version of the subtractive assembly approach for detecting differential reads between two groups of metagenomes. Please check CoSA out at https://sourceforge.net/projects/concurrentsa/...
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  • 19

    Trowel - Sequencing Error Corrector

    Error Correction Module for Illumina Sequencing Reads

    Trowel is an error correction module for Illumina sequencing reads, which is based on the k-mer spectrum approach. This tool is the first tool that uses a quality threshold instead of a coverage cutoff in order to extract trusted k-mers. This tool guarantees high accuracy and speed. This tool has been developed since 21. Jan. 2013 by Euncheon Lim in Prof. Dr. Detlef Weigel's Lab in Max-Planck Institute for Developmental Biology.
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  • 20

    Maree

    Marée des principaux ports de France

    Horaire, hauteurs et coefficients des marées sur plus de 100 ports français et quelques ports en Grande Bretagne. Application entièrement autonome faite à partir des constantes harmoniques fournies par Previ Mer. Toutes les heures locales affichées, le sont en horaires d'été et d'hiver. Le menu permet de calculer les marées et d'en donner les spécificités sur une journée ou sur un mois au choix. Fixez votre propre seuil (hauteur mini pour pratiquer la navigation ou maxi permettant la pêche à pied). Lister les grandes marées d'une période choisie et éventuellement stocker les horaires des marées basses dans votre agenda Saisissez une hauteur d'eau et définissez pour quels horaires elle sera atteinte ou pour tel horaire saisi quelle hauteur d'eau. ...
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  • 21
    mitoMaker

    mitoMaker

    mitoMaker - a mitochondria assembly and annotation script

    ...mitoMaker calls well known assemblers and algorithms, such as SOAPdenovo, MIRA and blast+ and parses their results providing easily readable outputs, such as FASTA, GENBANK, SEQUIN, PNG and others. General pipeline: 1-iterative De Novo assembly, with different k-mer values, trying to assemble a build that matches a target mitochondrial genome given. 2-searches for all mitochondrial gene features and circularization. 3-stores the best result found. 4-uses the best assembly as backbone for a reference based assembly, using MIRA and MITObim, trying to extend the mitogenome and close gaps. 5-annotates the best assembly, identifying the start and end position of each and every feature. 6-creates a folder with all the results (PNG, GENBANK, FASTA, SEQUIN, CAF, MAF and a stats logfile).
    Downloads: 0 This Week
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  • 22

    NGSimple

    NGS - Next-Generation Sequencing sIMulation PipeLinE

    ..../1.fastq/reads.fastq) from those designed libraries to assemblies. based on the parameters specified in CONFIG file. It will generate assmblies with different K-mer (./2.assembly/*), and choose the assembly with largest n50. Finally, it will produce a quartile summary and mummerplot for each for you to select a good parameter combination. insert_size.pl will take real Illumina data as
    Downloads: 0 This Week
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  • 23
    PriMux is a k-mer based library for genomic investigations, and for development of PCR signatures that may include degenerate base pairs
    Downloads: 3 This Week
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  • 24

    mitoMaker

    mitoMaker - a mitochondria pipeline wrapper script

    ...After various attempts to build different mitochondrial genomes in the lab I studied, a general pipeline started to appear: assemble reads with MIRA or SOAPdenovo-Trans, look for a scaffold/contig that matches a closely-related species, check it to see if all expected genomic features are present (since mitochondria is well conserved), check to see if the assembly might have circularized (since it's a circular DNA). If a feature was missing, or it hasn't circularized, try and assemble again with different assembler parameters (mainly k-mer). Rinse and repeat until the best build is found.
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  • 25

    Quikr

    Method for rapid reconstruction (phylotyping) of bacterial communities

    Quikr is a QUadratic, Iterative, K-mer based Reconstruction technique that utilizes sparsity promoting ideas from the field of compressed sensing to reconstruct the composition of a bacterial community (when the input data is 454-like pyrosequencing data). This extremely fast method comes with a default training database but can be custom trained. Typically reconstruction is accurate down to the genus level.
    Downloads: 0 This Week
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