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From: SourceForge.net <no...@so...> - 2008-04-14 11:48:20
|
GO website item #1937565, was opened at 2008-04-08 10:31 Message generated for change (Settings changed) made by girlwithglasses You can respond by visiting: https://sourceforge.net/tracker/?func=detail&atid=600519&aid=1937565&group_id=36855 Please note that this message will contain a full copy of the comment thread, including the initial issue submission, for this request, not just the latest update. Category: request feature Group: None >Status: Closed >Resolution: Accepted Priority: 5 Private: No Submitted By: Jane Lomax (jl242) Assigned to: girlwithglasses (girlwithglasses) Summary: New tool: FunNet Initial Comment: Subject: GO tool submission: FunNet From: "Corneliu Henegar" <cor...@he...> Date: Sat, 5 Apr 2008 00:35:50 +0200 To: go...@ge... CC: "Jean-Daniel Zucker" <jdz...@gm...>, "Clement Karine" <kar...@ps...> Dear Sir or Madam, Would you please consider for inclusion in the list of analytical tools based on Gene Ontology annotations a new tool, which I developed during my PhD, and whose purpose is to provide a biologically robust approach for exploring the modular architecture of transcriptional co-expression networks. Please find hereafter several details which I put together following the guidelines provided on the GO website in relation to the submission of new GO related tools. Tool name: FunNet - Functional Analysis of Transcriptional Networks URL of the tool: http://corneliu.henegar.info/FunNet.htm, http://www.funnet.info, http://www.funnet.ws Organization: Institut National de la Santé et de la Recherche Medicale (INSERM), Centre de Recherche des Cordeliers, UMRS 872, Paris, FRANCE URL of the organization: http://www.inserm.fr/en/home.html, http://www.crc.jussieu.fr/crc/index.php Tool type: microarray-related Brief description: "FunNet" was designed as an integrative tool for analyzing gene co-expression networks built from microarray expression data. The analytical model implemented in this tool involves two abstraction layers: transcriptional (i.e. gene expression profiles) and functional (i.e. biological themes indicating the roles of the analyzed transcripts). A functional analysis technique, which relies on Gene Ontology and KEGG annotations, is applied to extract a list of relevant biological themes from microarray gene expression data. Afterwards multiple-instance representations are built to relate relevant biological themes to their annotated transcripts. An original non-linear dynamical model is used to quantify the contextual proximity of relevant genomic themes based on their patterns of propagation in the gene co-expression network (i.e. capturing the similarity of the expression profiles of the transcriptional instances of annotating themes). In the end an unsupervised multiple-instance spectral clustering procedure is used to explore the modular architecture of the co-expression network by grouping together biological themes demonstrating a significant relationship in the co-expression network. Functional and transcriptional representations of the co-expression network are provided, together with detailed information on the contextual centrality of related transcripts and genomic themes. Availability: FunNet is currently provided as a standalone R package (http://www.r-project.org/). A web-based implementation of the FunNet tool is currently in an advanced stage of preparation and is already available from the following URLs: http://www.funnet.info, http://www.funnet.ws). The standalone R implementation can be run on any operating system for which an R environment implementation is available: Windows, Mac OS, various flavors of Linux and Unix. Both implementations of the FunNet tool are provided freely under the GNU General Public License 2.0. The R implementation can be downloaded from a dedicated web page (http://corneliu.henegar.info/FunNet.htm) as well as from the worldwide mirrors of CRAN (http://cran.r-project.org/mirrors.html). Associated publications: 1. Henegar C, Tordjman J, Achard V, Lacasa D, Cremer I, Guerre-Millo M, Poitou C, Basdevant A, Stich V, Viguerie N, Langin D, Bedossa P, Zucker J-D, Clement K. Adipose tissue transcriptomic signature highlights the pathologic relevance of extracellular matrix in human obesity. Genome Biology 2008, 9(1):R14. PMID: 18208606 2. Henegar C, Clément K, and Zucker JD (2006). Unsupervised multiple-instance learning for functional profiling of genomic data. Lecture Notes in Computer Science: ECML 2006. Springer Berlin / Heidelberg, 4212/2006 : 186-197. DOI: 10.1007/11871842. No PMID available. Two other manuscripts, describing in detail the FunNet analytical approach, are currently in an advanced stage of preparation. Technical details: the FunNet tool is using GO ontology files in the GO flat format, as provided on the GO web site, as well as the gene association files provided on the GO database web site (Stanford). Currently the FunNet analysis of transcriptional networks is available for three genomes: human, mouse and yeast. Annotation data will be updated automatically on a regular base (at least 6 times per year, possibly more frequently). Please let me know if you need me to provide further details about this tool. Thank you very much for considering this submission. Best wishes, Corneliu -------------------------------------- Corneliu Henegar MD, PhD INSERM UMRS 872 Eq. 7 Nutriomique Hotel-Dieu Hospital 1 Place du Parvis Notre-Dame 75004, Paris, FRANCE ------------------------------------- ---------------------------------------------------------------------- >Comment By: girlwithglasses (girlwithglasses) Date: 2008-04-14 11:48 Message: Logged In: YES user_id=473796 Originator: NO http://www.geneontology.org/GO.tools.microarray.shtml#funnet ---------------------------------------------------------------------- You can respond by visiting: https://sourceforge.net/tracker/?func=detail&atid=600519&aid=1937565&group_id=36855 |
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From: SourceForge.net <no...@so...> - 2008-04-14 11:45:55
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GO website item #1933405, was opened at 2008-04-03 14:31 Message generated for change (Comment added) made by girlwithglasses You can respond by visiting: https://sourceforge.net/tracker/?func=detail&atid=600519&aid=1933405&group_id=36855 Please note that this message will contain a full copy of the comment thread, including the initial issue submission, for this request, not just the latest update. Category: request feature Group: None >Status: Closed >Resolution: Accepted Priority: 5 Private: No Submitted By: Jane Lomax (jl242) Assigned to: girlwithglasses (girlwithglasses) Summary: new tool - ProfCom Initial Comment: New tool for the tools page: Tool name: ProfCom · URL for the tool: http://webclu.bio.wzw.tum.de/profcom/ · Name and URL of the organization that produced the tool : The Institute of Bioinformatics and Systems Biology (IBIS) of the Helmholtz Zentrum München, http://mips.gsf.de/ · Tool type: microarray-related · Brief description of tool : ProfCom is a web-based tool for the functional interpretation of a gene list that was identified to be related by experiments. A trait which makes ProfCom a unique tool is an ability to profile enrichments of not only available Gene Ontology (GO) terms but also of “complex functions”. A “Complex function” is constructed as Boolean combination of available GO terms. The complex functions inferred by ProfCom are more specific in comparison to single terms and describe more accurately the functional role of genes. · Is the tool web-based or standalone? :web-based · If the tool is standalone, which platforms can use it? (Windows / Mac / Unix / Linux / other)? For web-based tools it is assumed that all platforms can use the tool unless otherwise stated. · Is the tool free to academics? ProfCom is freely available at http://webclu.bio.wzw.tum.de/profcom/ · Any associated publications (please give PubMed ID if available) PMID: 16959266 ---------------------------------------------------------------------- >Comment By: girlwithglasses (girlwithglasses) Date: 2008-04-14 11:46 Message: Logged In: YES user_id=473796 Originator: NO http://www.geneontology.org/GO.tools.microarray.shtml#profcom ---------------------------------------------------------------------- Comment By: Jane Lomax (jl242) Date: 2008-04-03 14:34 Message: Logged In: YES user_id=451873 Originator: YES contact email: an...@gs... ---------------------------------------------------------------------- You can respond by visiting: https://sourceforge.net/tracker/?func=detail&atid=600519&aid=1933405&group_id=36855 |
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From: Midori H. <mi...@eb...> - 2008-04-12 11:00:15
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> just wondering where this email address leads to This list was automagically created by SourceForge when we set up the website tracker (every SF tracker has a list created, but I think not all are active). I don't know who's on it (but I am, apparently ...). > shouldn't the tracker be set up to email: > web...@ge... > ? It can be ... any SF tracker can be set to send email only on new submissions, or on every change to an item, and a project admin can plug in any single address we want (SF's default address is that of the automagically created list, which is why the website tracker messages have come here). Want me to change it? m |
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From: SourceForge.net <no...@so...> - 2008-04-10 22:10:15
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GO website item #1939761, was opened at 2008-04-10 15:10 Message generated for change (Tracker Item Submitted) made by Item Submitter You can respond by visiting: https://sourceforge.net/tracker/?func=detail&atid=600519&aid=1939761&group_id=36855 Please note that this message will contain a full copy of the comment thread, including the initial issue submission, for this request, not just the latest update. Category: None Group: None Status: Open Resolution: None Priority: 5 Private: No Submitted By: Chris Mungall (cmungall) Assigned to: Nobody/Anonymous (nobody) Summary: add pages for GO_REFs Initial Comment: There's no way to search these I suggest a simple statically generated html page, with a single URL for each REF (we can then fill this in in xrf_abbs) Also, is it just me that gets mixed up between bibliography, publications and references? http://www.geneontology.org/cgi-bin/biblio.cgi ---------------------------------------------------------------------- You can respond by visiting: https://sourceforge.net/tracker/?func=detail&atid=600519&aid=1939761&group_id=36855 |
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From: Chris M. <cj...@fr...> - 2008-04-10 22:03:32
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just wondering where this email address leads to shouldn't the tracker be set up to email: web...@ge... ? |
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From: SourceForge.net <no...@so...> - 2008-04-08 10:31:49
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GO website item #1937565, was opened at 2008-04-08 10:31 Message generated for change (Tracker Item Submitted) made by Item Submitter You can respond by visiting: https://sourceforge.net/tracker/?func=detail&atid=600519&aid=1937565&group_id=36855 Please note that this message will contain a full copy of the comment thread, including the initial issue submission, for this request, not just the latest update. Category: request feature Group: None Status: Open Resolution: None Priority: 5 Private: No Submitted By: Jane Lomax (jl242) Assigned to: girlwithglasses (girlwithglasses) Summary: New tool: FunNet Initial Comment: Subject: GO tool submission: FunNet From: "Corneliu Henegar" <cor...@he...> Date: Sat, 5 Apr 2008 00:35:50 +0200 To: go...@ge... CC: "Jean-Daniel Zucker" <jdz...@gm...>, "Clement Karine" <kar...@ps...> Dear Sir or Madam, Would you please consider for inclusion in the list of analytical tools based on Gene Ontology annotations a new tool, which I developed during my PhD, and whose purpose is to provide a biologically robust approach for exploring the modular architecture of transcriptional co-expression networks. Please find hereafter several details which I put together following the guidelines provided on the GO website in relation to the submission of new GO related tools. Tool name: FunNet - Functional Analysis of Transcriptional Networks URL of the tool: http://corneliu.henegar.info/FunNet.htm, http://www.funnet.info, http://www.funnet.ws Organization: Institut National de la Santé et de la Recherche Medicale (INSERM), Centre de Recherche des Cordeliers, UMRS 872, Paris, FRANCE URL of the organization: http://www.inserm.fr/en/home.html, http://www.crc.jussieu.fr/crc/index.php Tool type: microarray-related Brief description: "FunNet" was designed as an integrative tool for analyzing gene co-expression networks built from microarray expression data. The analytical model implemented in this tool involves two abstraction layers: transcriptional (i.e. gene expression profiles) and functional (i.e. biological themes indicating the roles of the analyzed transcripts). A functional analysis technique, which relies on Gene Ontology and KEGG annotations, is applied to extract a list of relevant biological themes from microarray gene expression data. Afterwards multiple-instance representations are built to relate relevant biological themes to their annotated transcripts. An original non-linear dynamical model is used to quantify the contextual proximity of relevant genomic themes based on their patterns of propagation in the gene co-expression network (i.e. capturing the similarity of the expression profiles of the transcriptional instances of annotating themes). In the end an unsupervised multiple-instance spectral clustering procedure is used to explore the modular architecture of the co-expression network by grouping together biological themes demonstrating a significant relationship in the co-expression network. Functional and transcriptional representations of the co-expression network are provided, together with detailed information on the contextual centrality of related transcripts and genomic themes. Availability: FunNet is currently provided as a standalone R package (http://www.r-project.org/). A web-based implementation of the FunNet tool is currently in an advanced stage of preparation and is already available from the following URLs: http://www.funnet.info, http://www.funnet.ws). The standalone R implementation can be run on any operating system for which an R environment implementation is available: Windows, Mac OS, various flavors of Linux and Unix. Both implementations of the FunNet tool are provided freely under the GNU General Public License 2.0. The R implementation can be downloaded from a dedicated web page (http://corneliu.henegar.info/FunNet.htm) as well as from the worldwide mirrors of CRAN (http://cran.r-project.org/mirrors.html). Associated publications: 1. Henegar C, Tordjman J, Achard V, Lacasa D, Cremer I, Guerre-Millo M, Poitou C, Basdevant A, Stich V, Viguerie N, Langin D, Bedossa P, Zucker J-D, Clement K. Adipose tissue transcriptomic signature highlights the pathologic relevance of extracellular matrix in human obesity. Genome Biology 2008, 9(1):R14. PMID: 18208606 2. Henegar C, Clément K, and Zucker JD (2006). Unsupervised multiple-instance learning for functional profiling of genomic data. Lecture Notes in Computer Science: ECML 2006. Springer Berlin / Heidelberg, 4212/2006 : 186-197. DOI: 10.1007/11871842. No PMID available. Two other manuscripts, describing in detail the FunNet analytical approach, are currently in an advanced stage of preparation. Technical details: the FunNet tool is using GO ontology files in the GO flat format, as provided on the GO web site, as well as the gene association files provided on the GO database web site (Stanford). Currently the FunNet analysis of transcriptional networks is available for three genomes: human, mouse and yeast. Annotation data will be updated automatically on a regular base (at least 6 times per year, possibly more frequently). Please let me know if you need me to provide further details about this tool. Thank you very much for considering this submission. Best wishes, Corneliu -------------------------------------- Corneliu Henegar MD, PhD INSERM UMRS 872 Eq. 7 Nutriomique Hotel-Dieu Hospital 1 Place du Parvis Notre-Dame 75004, Paris, FRANCE ------------------------------------- ---------------------------------------------------------------------- You can respond by visiting: https://sourceforge.net/tracker/?func=detail&atid=600519&aid=1937565&group_id=36855 |
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From: SourceForge.net <no...@so...> - 2008-04-03 14:34:04
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GO website item #1933405, was opened at 2008-04-03 14:31 Message generated for change (Comment added) made by jl242 You can respond by visiting: https://sourceforge.net/tracker/?func=detail&atid=600519&aid=1933405&group_id=36855 Please note that this message will contain a full copy of the comment thread, including the initial issue submission, for this request, not just the latest update. Category: request feature Group: None Status: Open Resolution: None Priority: 5 Private: No Submitted By: Jane Lomax (jl242) Assigned to: girlwithglasses (girlwithglasses) Summary: new tool - ProfCom Initial Comment: New tool for the tools page: Tool name: ProfCom · URL for the tool: http://webclu.bio.wzw.tum.de/profcom/ · Name and URL of the organization that produced the tool : The Institute of Bioinformatics and Systems Biology (IBIS) of the Helmholtz Zentrum München, http://mips.gsf.de/ · Tool type: microarray-related · Brief description of tool : ProfCom is a web-based tool for the functional interpretation of a gene list that was identified to be related by experiments. A trait which makes ProfCom a unique tool is an ability to profile enrichments of not only available Gene Ontology (GO) terms but also of “complex functions”. A “Complex function” is constructed as Boolean combination of available GO terms. The complex functions inferred by ProfCom are more specific in comparison to single terms and describe more accurately the functional role of genes. · Is the tool web-based or standalone? :web-based · If the tool is standalone, which platforms can use it? (Windows / Mac / Unix / Linux / other)? For web-based tools it is assumed that all platforms can use the tool unless otherwise stated. · Is the tool free to academics? ProfCom is freely available at http://webclu.bio.wzw.tum.de/profcom/ · Any associated publications (please give PubMed ID if available) PMID: 16959266 ---------------------------------------------------------------------- >Comment By: Jane Lomax (jl242) Date: 2008-04-03 14:34 Message: Logged In: YES user_id=451873 Originator: YES contact email: an...@gs... ---------------------------------------------------------------------- You can respond by visiting: https://sourceforge.net/tracker/?func=detail&atid=600519&aid=1933405&group_id=36855 |
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From: SourceForge.net <no...@so...> - 2008-04-03 14:31:31
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GO website item #1933405, was opened at 2008-04-03 14:31 Message generated for change (Tracker Item Submitted) made by Item Submitter You can respond by visiting: https://sourceforge.net/tracker/?func=detail&atid=600519&aid=1933405&group_id=36855 Please note that this message will contain a full copy of the comment thread, including the initial issue submission, for this request, not just the latest update. Category: request feature Group: None Status: Open Resolution: None Priority: 5 Private: No Submitted By: Jane Lomax (jl242) Assigned to: girlwithglasses (girlwithglasses) Summary: new tool - ProfCom Initial Comment: New tool for the tools page: Tool name: ProfCom · URL for the tool: http://webclu.bio.wzw.tum.de/profcom/ · Name and URL of the organization that produced the tool : The Institute of Bioinformatics and Systems Biology (IBIS) of the Helmholtz Zentrum München, http://mips.gsf.de/ · Tool type: microarray-related · Brief description of tool : ProfCom is a web-based tool for the functional interpretation of a gene list that was identified to be related by experiments. A trait which makes ProfCom a unique tool is an ability to profile enrichments of not only available Gene Ontology (GO) terms but also of “complex functions”. A “Complex function” is constructed as Boolean combination of available GO terms. The complex functions inferred by ProfCom are more specific in comparison to single terms and describe more accurately the functional role of genes. · Is the tool web-based or standalone? :web-based · If the tool is standalone, which platforms can use it? (Windows / Mac / Unix / Linux / other)? For web-based tools it is assumed that all platforms can use the tool unless otherwise stated. · Is the tool free to academics? ProfCom is freely available at http://webclu.bio.wzw.tum.de/profcom/ · Any associated publications (please give PubMed ID if available) PMID: 16959266 ---------------------------------------------------------------------- You can respond by visiting: https://sourceforge.net/tracker/?func=detail&atid=600519&aid=1933405&group_id=36855 |
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From: SourceForge.net <no...@so...> - 2008-02-25 12:53:11
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GO website item #1899867, was opened at 2008-02-22 19:32 Message generated for change (Comment added) made by gomidori You can respond by visiting: https://sourceforge.net/tracker/?func=detail&atid=600519&aid=1899867&group_id=36855 Please note that this message will contain a full copy of the comment thread, including the initial issue submission, for this request, not just the latest update. Category: None Group: None Status: Open Resolution: None Priority: 5 Private: No Submitted By: Tanya Berardini (tairtb) Assigned to: Nobody/Anonymous (nobody) Summary: Sensu in documentation Initial Comment: http://www.geneontology.org/GO.usage.shtml#sensu This section needs to be removed from the documentation since we no longer support sensu terms. :) ---------------------------------------------------------------------- >Comment By: Midori Harris (gomidori) Date: 2008-02-25 12:53 Message: Logged In: YES user_id=436423 Originator: NO Could just change the last sentence to ... Where different terms are required to represent different types of process or component observed in different taxa, the terms are named and definued based on what features distinguish them from the parent(s) and sibling(s). Narrow or related synonyms may be included that name the taxon/taxa to which the term is known to apply. ... or some more elegant wording thereof. possible example: flocculation GO:0000128 [i] flocculation via cell wall protein-carbohydrate interaction GO:0000501 narrow synonym 'flocculation (sensu Saccharomyces)' [i] flocculation via extracellular polymer m ---------------------------------------------------------------------- Comment By: girlwithglasses (girlwithglasses) Date: 2008-02-25 10:39 Message: Logged In: YES user_id=473796 Originator: NO I'll remove the section from that page. Any suggestions on a rewording for this section: Species-specific terms The Gene Ontology aims to provide a controlled vocabulary that can be used to describe any organism; nevertheless, many functions, processes and components are not common to all life forms. The convention is to include any term that can apply to more than one taxonomic class of organism. To specify the class of organisms to which a term is applicable, GO uses the designator sensu, 'in the sense of'; for example, trichome differentiation (sensu Magnoliophyta) represents the differentiation of plant hair cells (trichomes). It would be useful to have some kind of documentation about how we handle species-specific stuff. ---------------------------------------------------------------------- You can respond by visiting: https://sourceforge.net/tracker/?func=detail&atid=600519&aid=1899867&group_id=36855 |
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From: SourceForge.net <no...@so...> - 2008-02-25 10:39:53
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GO website item #1899867, was opened at 2008-02-22 19:32 Message generated for change (Comment added) made by girlwithglasses You can respond by visiting: https://sourceforge.net/tracker/?func=detail&atid=600519&aid=1899867&group_id=36855 Please note that this message will contain a full copy of the comment thread, including the initial issue submission, for this request, not just the latest update. Category: None Group: None Status: Open Resolution: None Priority: 5 Private: No Submitted By: Tanya Berardini (tairtb) Assigned to: Nobody/Anonymous (nobody) Summary: Sensu in documentation Initial Comment: http://www.geneontology.org/GO.usage.shtml#sensu This section needs to be removed from the documentation since we no longer support sensu terms. :) ---------------------------------------------------------------------- >Comment By: girlwithglasses (girlwithglasses) Date: 2008-02-25 10:39 Message: Logged In: YES user_id=473796 Originator: NO I'll remove the section from that page. Any suggestions on a rewording for this section: Species-specific terms The Gene Ontology aims to provide a controlled vocabulary that can be used to describe any organism; nevertheless, many functions, processes and components are not common to all life forms. The convention is to include any term that can apply to more than one taxonomic class of organism. To specify the class of organisms to which a term is applicable, GO uses the designator sensu, 'in the sense of'; for example, trichome differentiation (sensu Magnoliophyta) represents the differentiation of plant hair cells (trichomes). It would be useful to have some kind of documentation about how we handle species-specific stuff. ---------------------------------------------------------------------- You can respond by visiting: https://sourceforge.net/tracker/?func=detail&atid=600519&aid=1899867&group_id=36855 |
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From: SourceForge.net <no...@so...> - 2008-02-22 19:32:09
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GO website item #1899867, was opened at 2008-02-22 11:32 Message generated for change (Tracker Item Submitted) made by Item Submitter You can respond by visiting: https://sourceforge.net/tracker/?func=detail&atid=600519&aid=1899867&group_id=36855 Please note that this message will contain a full copy of the comment thread, including the initial issue submission, for this request, not just the latest update. Category: None Group: None Status: Open Resolution: None Priority: 5 Private: No Submitted By: Tanya Berardini (tairtb) Assigned to: Nobody/Anonymous (nobody) Summary: Sensu in documentation Initial Comment: http://www.geneontology.org/GO.usage.shtml#sensu This section needs to be removed from the documentation since we no longer support sensu terms. :) ---------------------------------------------------------------------- You can respond by visiting: https://sourceforge.net/tracker/?func=detail&atid=600519&aid=1899867&group_id=36855 |
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From: SourceForge.net <no...@so...> - 2007-09-11 22:27:13
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GO website item #1787118, was opened at 2007-09-03 07:11 Message generated for change (Comment added) made by cmungall You can respond by visiting: https://sourceforge.net/tracker/?func=detail&atid=600519&aid=1787118&group_id=36855 Please note that this message will contain a full copy of the comment thread, including the initial issue submission, for this request, not just the latest update. Category: None Group: None Status: Open Resolution: None Priority: 5 Private: No Submitted By: Midori Harris (gomidori) Assigned to: girlwithglasses (girlwithglasses) Summary: format doc links awry Initial Comment: On the ontology downloads page (http://www.geneontology.org/GO.downloads.ontology.shtml) ... I've just noticed that two of the links that are supposed to go to format documentation don't do what they say on the tin: for both OBO-XML format and OWL format, there are amigo.geneontology.org URLs that are being redirected to the "GO Related Software Libraries" page -- which says nothing about the formats! The OBO Download Matrix page at BBOP (http://www.berkeleybop.org/ontologies/) has the same problem ... can you chase Chris and get these links to point somewhere more enlightening? thanx, m ---------------------------------------------------------------------- >Comment By: Chris Mungall (cmungall) Date: 2007-09-11 15:27 Message: Logged In: YES user_id=254723 Originator: NO fixed GO.formats.shtml ---------------------------------------------------------------------- You can respond by visiting: https://sourceforge.net/tracker/?func=detail&atid=600519&aid=1787118&group_id=36855 |
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From: SourceForge.net <no...@so...> - 2007-09-03 15:13:26
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GO website item #1787118, was opened at 2007-09-03 14:11 Message generated for change (Tracker Item Submitted) made by Item Submitter You can respond by visiting: https://sourceforge.net/tracker/?func=detail&atid=600519&aid=1787118&group_id=36855 Please note that this message will contain a full copy of the comment thread, including the initial issue submission, for this request, not just the latest update. Category: None Group: None Status: Open Resolution: None Priority: 5 Private: No Submitted By: Midori Harris (gomidori) Assigned to: girlwithglasses (girlwithglasses) Summary: format doc links awry Initial Comment: On the ontology downloads page (http://www.geneontology.org/GO.downloads.ontology.shtml) ... I've just noticed that two of the links that are supposed to go to format documentation don't do what they say on the tin: for both OBO-XML format and OWL format, there are amigo.geneontology.org URLs that are being redirected to the "GO Related Software Libraries" page -- which says nothing about the formats! The OBO Download Matrix page at BBOP (http://www.berkeleybop.org/ontologies/) has the same problem ... can you chase Chris and get these links to point somewhere more enlightening? thanx, m ---------------------------------------------------------------------- You can respond by visiting: https://sourceforge.net/tracker/?func=detail&atid=600519&aid=1787118&group_id=36855 |
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From: SourceForge.net <no...@so...> - 2007-08-22 16:37:53
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GO website item #1778391, was opened at 2007-08-21 08:37 Message generated for change (Comment added) made by jenclark You can respond by visiting: https://sourceforge.net/tracker/?func=detail&atid=600519&aid=1778391&group_id=36855 Please note that this message will contain a full copy of the comment thread, including the initial issue submission, for this request, not just the latest update. Category: request feature Group: None Status: Closed Resolution: Fixed Priority: 5 Private: No Submitted By: Jennifer I Clark (jenclark) Assigned to: girlwithglasses (girlwithglasses) Summary: email archive Initial Comment: Hi, The go email archives are now at http://genetics.stanford.edu/go-email/ Would it be possible to replace this info on ftp access with the new info on the html address? The ftp access is now gone. The text could say: " There may be discussion of a given term in the GO e-mail archive and it can be useful to search the archive for pertinent e-mails. You can use the search facility on the website, or for a more sophisticated search you can download the e-mail archive and carry out a text search. To download the e-mail archive visit: http://www.geneontology.org/GO.curator.requests.shtml#history" Thanks, Jen ---------------------------------------------------------------------- >Comment By: Jennifer I Clark (jenclark) Date: 2007-08-22 16:37 Message: Logged In: YES user_id=735846 Originator: YES Thanks. There was also an html archive to add but I've just put that in myself to save time. Jen ---------------------------------------------------------------------- Comment By: girlwithglasses (girlwithglasses) Date: 2007-08-22 16:20 Message: Logged In: YES user_id=473796 Originator: NO removed the reference to getting the GO email archive by ftp. ---------------------------------------------------------------------- You can respond by visiting: https://sourceforge.net/tracker/?func=detail&atid=600519&aid=1778391&group_id=36855 |
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From: SourceForge.net <no...@so...> - 2007-08-22 16:20:40
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GO website item #1778391, was opened at 2007-08-21 08:37 Message generated for change (Settings changed) made by girlwithglasses You can respond by visiting: https://sourceforge.net/tracker/?func=detail&atid=600519&aid=1778391&group_id=36855 Please note that this message will contain a full copy of the comment thread, including the initial issue submission, for this request, not just the latest update. Category: request feature Group: None >Status: Closed >Resolution: Fixed Priority: 5 Private: No Submitted By: Jennifer I Clark (jenclark) >Assigned to: girlwithglasses (girlwithglasses) Summary: email archive Initial Comment: Hi, The go email archives are now at http://genetics.stanford.edu/go-email/ Would it be possible to replace this info on ftp access with the new info on the html address? The ftp access is now gone. The text could say: " There may be discussion of a given term in the GO e-mail archive and it can be useful to search the archive for pertinent e-mails. You can use the search facility on the website, or for a more sophisticated search you can download the e-mail archive and carry out a text search. To download the e-mail archive visit: http://www.geneontology.org/GO.curator.requests.shtml#history" Thanks, Jen ---------------------------------------------------------------------- >Comment By: girlwithglasses (girlwithglasses) Date: 2007-08-22 16:20 Message: Logged In: YES user_id=473796 Originator: NO removed the reference to getting the GO email archive by ftp. ---------------------------------------------------------------------- You can respond by visiting: https://sourceforge.net/tracker/?func=detail&atid=600519&aid=1778391&group_id=36855 |
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From: SourceForge.net <no...@so...> - 2007-08-21 08:37:17
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GO website item #1778391, was opened at 2007-08-21 08:37 Message generated for change (Tracker Item Submitted) made by Item Submitter You can respond by visiting: https://sourceforge.net/tracker/?func=detail&atid=600519&aid=1778391&group_id=36855 Please note that this message will contain a full copy of the comment thread, including the initial issue submission, for this request, not just the latest update. Category: request feature Group: None Status: Open Resolution: None Priority: 5 Private: No Submitted By: Jennifer I Clark (jenclark) Assigned to: Nobody/Anonymous (nobody) Summary: email archive Initial Comment: Hi, The go email archives are now at http://genetics.stanford.edu/go-email/ Would it be possible to replace this info on ftp access with the new info on the html address? The ftp access is now gone. The text could say: " There may be discussion of a given term in the GO e-mail archive and it can be useful to search the archive for pertinent e-mails. You can use the search facility on the website, or for a more sophisticated search you can download the e-mail archive and carry out a text search. To download the e-mail archive visit: http://www.geneontology.org/GO.curator.requests.shtml#history" Thanks, Jen ---------------------------------------------------------------------- You can respond by visiting: https://sourceforge.net/tracker/?func=detail&atid=600519&aid=1778391&group_id=36855 |
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From: SourceForge.net <no...@so...> - 2007-06-19 12:55:39
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GO website item #1111466, was opened at 2005-01-28 14:28 Message generated for change (Comment added) made by gomidori You can respond by visiting: https://sourceforge.net/tracker/?func=detail&atid=600519&aid=1111466&group_id=36855 Please note that this message will contain a full copy of the comment thread, including the initial issue submission, for this request, not just the latest update. Category: request feature Group: None >Status: Closed >Resolution: Out of Date Priority: 5 Private: No Submitted By: Jennifer I Clark (jenclark) Assigned to: Nobody/Anonymous (nobody) Summary: new obo docs Initial Comment: Chris has rewritten the OBO docs and he's not sure whether to have them on the GO site or the GO database site. I had a chat with Midori and we agreed it could go on either as long as it's stable and we can link directly to it. I've said that to Chris and also that if he has any doubt about their ability to maintain it that we're happy to host it. He hasn't got back to me yet. His initial e-mail is below. Jen OK, the document is now checked in as go-dev/doc/obo_format_spec.txt (this was the original filename) I've also cvs tagged it as 'obo_format_spec-1_2' I've also checked in a Makefile for auto-generating the html and pdf from the txt file, and checked in the html and pdf themselves. You can see the results here: http://www.godatabase.org/dev/doc/obo_format_spec.txt http://www.godatabase.org/dev/doc/obo_format_spec.html http://www.godatabase.org/dev/doc/obo_format_spec.pdf I haven't created any links to this yet Jen: I don't know whether it makes sense to replicate this documentation across go-dev and go, or whether it makes sense to just have it at one place. If you want to keep it at go, the parameters for asciidoc can be changed so stylesheets aren't used, or you can just fix it to use to go stylesheet. I think it may be problematic to embed the autogenerated html inside the single page we have now for all the formats. However, I think this page needs changed anyway - we should tuck away the old docs on the old format, and the docs on the rdf-xml seem to make more sense on the go-dev site... ---------------------------------------------------------------------- >Comment By: Midori Harris (gomidori) Date: 2007-06-19 12:55 Message: Logged In: YES user_id=436423 Originator: NO all righty then! ---------------------------------------------------------------------- Comment By: Jennifer I Clark (jenclark) Date: 2007-06-19 12:53 Message: Logged In: YES user_id=735846 Originator: YES Good idea. Practically prehistoric in GO terms. Jen ---------------------------------------------------------------------- Comment By: Midori Harris (gomidori) Date: 2007-06-19 12:49 Message: Logged In: YES user_id=436423 Originator: NO this seems rather out of date. shall we close it? m ---------------------------------------------------------------------- Comment By: Jennifer I Clark (jenclark) Date: 2005-02-01 11:07 Message: Logged In: YES user_id=735846 Chris suggests that I install asciidoc here and have a go of generating the page from the obo doc they've written. I'm going to have a try of that since it looks like it could be useful for other things too. He also has this suggestion for how to integrate it with the format guide: "keep GO.formats.html, since there's a zillion hrefs pointing to it make this page contain just a *summary* of each format (someone has to write this - bagsy not me!). then there will be a link to a detailed description of the format, which a programmer can use to write a parser. that page can live at either godb or go. this page is the autogenerated output of asciidoc.py on the obo_format.txt file in go-dev/doc cvs. the summary will help people who want to just get a feel for the format, maybe inspect it by eye and look for whatever (tho they should of course use dag edit ot amigo for this). the detailed format page is for hardcore programmers. this is in addition to the changes and notification that has to be sent to gofriends" Would you all be happy with this plan? Jen ---------------------------------------------------------------------- You can respond by visiting: https://sourceforge.net/tracker/?func=detail&atid=600519&aid=1111466&group_id=36855 |
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From: SourceForge.net <no...@so...> - 2007-06-19 12:53:49
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GO website item #1111466, was opened at 2005-01-28 14:28 Message generated for change (Comment added) made by jenclark You can respond by visiting: https://sourceforge.net/tracker/?func=detail&atid=600519&aid=1111466&group_id=36855 Please note that this message will contain a full copy of the comment thread, including the initial issue submission, for this request, not just the latest update. Category: request feature Group: None Status: Open Resolution: None Priority: 5 Private: No Submitted By: Jennifer I Clark (jenclark) Assigned to: Nobody/Anonymous (nobody) Summary: new obo docs Initial Comment: Chris has rewritten the OBO docs and he's not sure whether to have them on the GO site or the GO database site. I had a chat with Midori and we agreed it could go on either as long as it's stable and we can link directly to it. I've said that to Chris and also that if he has any doubt about their ability to maintain it that we're happy to host it. He hasn't got back to me yet. His initial e-mail is below. Jen OK, the document is now checked in as go-dev/doc/obo_format_spec.txt (this was the original filename) I've also cvs tagged it as 'obo_format_spec-1_2' I've also checked in a Makefile for auto-generating the html and pdf from the txt file, and checked in the html and pdf themselves. You can see the results here: http://www.godatabase.org/dev/doc/obo_format_spec.txt http://www.godatabase.org/dev/doc/obo_format_spec.html http://www.godatabase.org/dev/doc/obo_format_spec.pdf I haven't created any links to this yet Jen: I don't know whether it makes sense to replicate this documentation across go-dev and go, or whether it makes sense to just have it at one place. If you want to keep it at go, the parameters for asciidoc can be changed so stylesheets aren't used, or you can just fix it to use to go stylesheet. I think it may be problematic to embed the autogenerated html inside the single page we have now for all the formats. However, I think this page needs changed anyway - we should tuck away the old docs on the old format, and the docs on the rdf-xml seem to make more sense on the go-dev site... ---------------------------------------------------------------------- >Comment By: Jennifer I Clark (jenclark) Date: 2007-06-19 12:53 Message: Logged In: YES user_id=735846 Originator: YES Good idea. Practically prehistoric in GO terms. Jen ---------------------------------------------------------------------- Comment By: Midori Harris (gomidori) Date: 2007-06-19 12:49 Message: Logged In: YES user_id=436423 Originator: NO this seems rather out of date. shall we close it? m ---------------------------------------------------------------------- Comment By: Jennifer I Clark (jenclark) Date: 2005-02-01 11:07 Message: Logged In: YES user_id=735846 Chris suggests that I install asciidoc here and have a go of generating the page from the obo doc they've written. I'm going to have a try of that since it looks like it could be useful for other things too. He also has this suggestion for how to integrate it with the format guide: "keep GO.formats.html, since there's a zillion hrefs pointing to it make this page contain just a *summary* of each format (someone has to write this - bagsy not me!). then there will be a link to a detailed description of the format, which a programmer can use to write a parser. that page can live at either godb or go. this page is the autogenerated output of asciidoc.py on the obo_format.txt file in go-dev/doc cvs. the summary will help people who want to just get a feel for the format, maybe inspect it by eye and look for whatever (tho they should of course use dag edit ot amigo for this). the detailed format page is for hardcore programmers. this is in addition to the changes and notification that has to be sent to gofriends" Would you all be happy with this plan? Jen ---------------------------------------------------------------------- You can respond by visiting: https://sourceforge.net/tracker/?func=detail&atid=600519&aid=1111466&group_id=36855 |
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From: SourceForge.net <no...@so...> - 2007-06-19 12:49:30
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GO website item #1111466, was opened at 2005-01-28 14:28 Message generated for change (Comment added) made by gomidori You can respond by visiting: https://sourceforge.net/tracker/?func=detail&atid=600519&aid=1111466&group_id=36855 Please note that this message will contain a full copy of the comment thread, including the initial issue submission, for this request, not just the latest update. Category: request feature Group: None Status: Open Resolution: None Priority: 5 Private: No Submitted By: Jennifer I Clark (jenclark) Assigned to: Nobody/Anonymous (nobody) Summary: new obo docs Initial Comment: Chris has rewritten the OBO docs and he's not sure whether to have them on the GO site or the GO database site. I had a chat with Midori and we agreed it could go on either as long as it's stable and we can link directly to it. I've said that to Chris and also that if he has any doubt about their ability to maintain it that we're happy to host it. He hasn't got back to me yet. His initial e-mail is below. Jen OK, the document is now checked in as go-dev/doc/obo_format_spec.txt (this was the original filename) I've also cvs tagged it as 'obo_format_spec-1_2' I've also checked in a Makefile for auto-generating the html and pdf from the txt file, and checked in the html and pdf themselves. You can see the results here: http://www.godatabase.org/dev/doc/obo_format_spec.txt http://www.godatabase.org/dev/doc/obo_format_spec.html http://www.godatabase.org/dev/doc/obo_format_spec.pdf I haven't created any links to this yet Jen: I don't know whether it makes sense to replicate this documentation across go-dev and go, or whether it makes sense to just have it at one place. If you want to keep it at go, the parameters for asciidoc can be changed so stylesheets aren't used, or you can just fix it to use to go stylesheet. I think it may be problematic to embed the autogenerated html inside the single page we have now for all the formats. However, I think this page needs changed anyway - we should tuck away the old docs on the old format, and the docs on the rdf-xml seem to make more sense on the go-dev site... ---------------------------------------------------------------------- >Comment By: Midori Harris (gomidori) Date: 2007-06-19 12:49 Message: Logged In: YES user_id=436423 Originator: NO this seems rather out of date. shall we close it? m ---------------------------------------------------------------------- Comment By: Jennifer I Clark (jenclark) Date: 2005-02-01 11:07 Message: Logged In: YES user_id=735846 Chris suggests that I install asciidoc here and have a go of generating the page from the obo doc they've written. I'm going to have a try of that since it looks like it could be useful for other things too. He also has this suggestion for how to integrate it with the format guide: "keep GO.formats.html, since there's a zillion hrefs pointing to it make this page contain just a *summary* of each format (someone has to write this - bagsy not me!). then there will be a link to a detailed description of the format, which a programmer can use to write a parser. that page can live at either godb or go. this page is the autogenerated output of asciidoc.py on the obo_format.txt file in go-dev/doc cvs. the summary will help people who want to just get a feel for the format, maybe inspect it by eye and look for whatever (tho they should of course use dag edit ot amigo for this). the detailed format page is for hardcore programmers. this is in addition to the changes and notification that has to be sent to gofriends" Would you all be happy with this plan? Jen ---------------------------------------------------------------------- You can respond by visiting: https://sourceforge.net/tracker/?func=detail&atid=600519&aid=1111466&group_id=36855 |
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From: SourceForge.net <no...@so...> - 2007-06-19 12:45:36
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GO website item #1618963, was opened at 2006-12-19 18:47 Message generated for change (Comment added) made by gomidori You can respond by visiting: https://sourceforge.net/tracker/?func=detail&atid=600519&aid=1618963&group_id=36855 Please note that this message will contain a full copy of the comment thread, including the initial issue submission, for this request, not just the latest update. Category: request feature Group: None Status: Open Resolution: None Priority: 5 Private: No Submitted By: fcouto (fcouto) >Assigned to: girlwithglasses (girlwithglasses) Summary: web tools update Initial Comment: 1. Could you change the name of the institution for the FuSSiMeG tool to: "XLDB Group, Faculdade de Ciências da Universidade de Lisboa" to be cohenrent with the GOAnnotator and ProteInOn tools. 2. Could you add the following associated publications to FuSSiMeG: - F. Couto, M. Silva and P. Coutinho, Measuring Semantic Similarity between Gene Ontology Terms, DKE - Data & Knowledge Engineering, Elsevier Science. - F. Couto and M. Silva and P. Coutinho, Semantic Similarity over the Gene Ontology: Family Correlation and Selecting Disjunctive Ancestors, ACM CIKM - Conference in Information and Knowledge Management, October, 2005 - F. Couto, M. Silva and P. Coutinho, Implementation of a Functional Semantic Similarity Measure between Gene-Products, Department of Informatics, University of Lisbon, DI/FCUL TR 03--29, November, 2003 3. and to GOAnnotator: - F. Couto, M. Silva, V. Lee, E. Dimmer, E. Camon, R. Apweiler, H. Kirsch, D. Rebholz-Schuhmann, GOAnnotator: linking electronic protein GO annotation to evidence text. Journal of Biomedical Discovery and Collaboration - F. Couto and M. Silva, Chapter XV: Mining the BioLiterature: towards automatic annotation of genes and proteins. Advanced Data Mining Technologies in Bioinformatics, 2006, ISBN: 1-59140-863-6 ---------------------------------------------------------------------- >Comment By: Midori Harris (gomidori) Date: 2007-06-19 12:45 Message: Logged In: YES user_id=436423 Originator: NO this has been overlooked! can it be done soon? ta, m ---------------------------------------------------------------------- You can respond by visiting: https://sourceforge.net/tracker/?func=detail&atid=600519&aid=1618963&group_id=36855 |
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From: SourceForge.net <no...@so...> - 2007-06-19 11:43:28
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GO website item #1669876, was opened at 2007-02-27 11:23 Message generated for change (Comment added) made by gomidori You can respond by visiting: https://sourceforge.net/tracker/?func=detail&atid=600519&aid=1669876&group_id=36855 Please note that this message will contain a full copy of the comment thread, including the initial issue submission, for this request, not just the latest update. Category: None Group: None Status: Open Resolution: None Priority: 5 Private: No Submitted By: Jane Lomax (jl242) Assigned to: girlwithglasses (girlwithglasses) Summary: Move editor guides to wiki Initial Comment: Hi - I think we should move the editor guide and the cvs guide to the internal wiki at some point: http://www.geneontology.org/GO.CVS.help.shtml http://www.geneontology.org/GO.contents.curator.guides.shtml these are internal docs and there's no reason to keep them on the public website when there's somewhere else for them to go. thanks! Jane ---------------------------------------------------------------------- >Comment By: Midori Harris (gomidori) Date: 2007-06-19 11:43 Message: Logged In: YES user_id=436423 Originator: NO Agreed about GO.contents.curator.guides.shtml, but GO.CVS.help.shtml is for users so should stay on the web page. m ---------------------------------------------------------------------- You can respond by visiting: https://sourceforge.net/tracker/?func=detail&atid=600519&aid=1669876&group_id=36855 |
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From: SourceForge.net <no...@so...> - 2007-06-19 11:41:48
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GO website item #1658103, was opened at 2007-02-12 15:00 Message generated for change (Comment added) made by gomidori You can respond by visiting: https://sourceforge.net/tracker/?func=detail&atid=600519&aid=1658103&group_id=36855 Please note that this message will contain a full copy of the comment thread, including the initial issue submission, for this request, not just the latest update. Category: report error Group: None >Status: Closed >Resolution: Fixed Priority: 5 Private: No Submitted By: Jane Lomax (jl242) Assigned to: girlwithglasses (girlwithglasses) Summary: go tools - remove GOODIES Initial Comment: Looks like GOODIES in microarray tools no longer active. I've mailed the developers (12 Feb) and if we don't hear anything back in a week or so, lets take them off. Jane ---------------------------------------------------------------------- >Comment By: Midori Harris (gomidori) Date: 2007-06-19 11:41 Message: Logged In: YES user_id=436423 Originator: NO seems this got done ... ---------------------------------------------------------------------- Comment By: Jane Lomax (jl242) Date: 2007-02-12 15:02 Message: Logged In: YES user_id=451873 Originator: YES Well, those email addresses no longer work either, so just remove it whenever... Jane ---------------------------------------------------------------------- You can respond by visiting: https://sourceforge.net/tracker/?func=detail&atid=600519&aid=1658103&group_id=36855 |
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From: SourceForge.net <no...@so...> - 2007-06-19 11:39:23
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GO website item #1642078, was opened at 2007-01-23 01:12 Message generated for change (Comment added) made by gomidori You can respond by visiting: https://sourceforge.net/tracker/?func=detail&atid=600519&aid=1642078&group_id=36855 Please note that this message will contain a full copy of the comment thread, including the initial issue submission, for this request, not just the latest update. >Category: request feature Group: None >Status: Closed >Resolution: Accepted Priority: 5 Private: No Submitted By: Eurie Hong (eurie) >Assigned to: girlwithglasses (girlwithglasses) Summary: Links to unfiltered UniProt files on downloads page Initial Comment: >From the GOC meeting, an action item was for the AmiGO working group to come up with a proposal for how to link to the unfiltered UniProt files on the downloads page: http://www.geneontology.org/GO.current.annotations.shtml Because there would be two UniProt files on that page, the distinction between the files needs to be clearly stated. ---------------------------------------------------------------------- >Comment By: Midori Harris (gomidori) Date: 2007-06-19 11:39 Message: Logged In: YES user_id=436423 Originator: NO this got done a little while back ---------------------------------------------------------------------- You can respond by visiting: https://sourceforge.net/tracker/?func=detail&atid=600519&aid=1642078&group_id=36855 |
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From: SourceForge.net <no...@so...> - 2007-06-19 11:32:33
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GO website item #1338308, was opened at 2005-10-26 10:18 Message generated for change (Comment added) made by gomidori You can respond by visiting: https://sourceforge.net/tracker/?func=detail&atid=600519&aid=1338308&group_id=36855 Please note that this message will contain a full copy of the comment thread, including the initial issue submission, for this request, not just the latest update. Category: None Group: None >Status: Closed >Resolution: Fixed Priority: 5 Private: No Submitted By: Valerie Wood (val_wood) Assigned to: Nobody/Anonymous (nobody) Summary: query evidence code hierarchy documentation Initial Comment: Added 2000-11-08: Heather has seen cases where a paper presents several lines of evidence supporting a conclusion, of which each line of evidence alone is sufficient to annotate to a higher-level (more generic) node, but combining the lines of evidence gives the author (or curator) enough data to support annotating to a lower-level (more specific) node. We've decided to annotate each line of evidence singly, with the appropriate evidence code, for the higher node (e.g. have a line for IMP, another line for IPI, for one GO ID). The annotation to the lower node can then be included with 'TAS' as the evidence; cite the paper if the author draws the conclusion. If the curator draws the conclusion, keep some record of what went into the decision. "If the curator draws the conclusion, keep some record of what went into the decision." Perhaps thsi needs to be updated; this is a valid type of IC annotation where the GO IDS of all of the higher level terms used to make the more granular association are included in the with column (pipe separated). I don't think this type of curator inference is documented under IC.....perhaps it should be ---------------------------------------------------------------------- >Comment By: Midori Harris (gomidori) Date: 2007-06-19 11:32 Message: Logged In: YES user_id=436423 Originator: NO the offending 'hierarchy' blurb is now gone, and, with more changes to the documentation, including IC, in the works, it seems it's time to close this. ---------------------------------------------------------------------- Comment By: Midori Harris (gomidori) Date: 2005-11-09 16:14 Message: Logged In: YES user_id=436423 I'm quite willing to lose the hierachy blurb ... it's mainly inertia that has kept in on the page for the past couple years anyway. m ---------------------------------------------------------------------- Comment By: Valerie Wood (val_wood) Date: 2005-11-02 09:53 Message: Logged In: YES user_id=516865 Hi Karen, I agree with your comments about ditching statements refering to an 'evidence code heirarchy'. They are misleading and open to misinterpretation. It has always worried me that an IDA from a high throughput screen is given more credability than a high quality ISS (or any other code). As you say the reliability of the annotation depends on the experiment/author/curator interpretation/graularity of inference. The statement about ranking evidence types is not only misleading but untrue. ---------------------------------------------------------------------- Comment By: Karen Christie (kchris) Date: 2005-11-01 23:28 Message: Logged In: YES user_id=473890 good suggestion about using IC now. I agree. ... speaking of the "evidence code hierarchy", quoting from the documentation: "The evidence fields can be thought of in a loose hierarchy of reliability: ...TAS/IDA ......IMP/IGI/IPI ......ISS/IEP ......NAS .........IEA This hierarchy should not be interpreted as a rigid ranking of evidence types; users can and should form their own conclusions as to the reliability of each type of evidence and each individual annotation. It is a loose hierarchy also partly because the strength of the evidence will also depend on to what resolution you are annotating, and because there is a range of reliability within each evidence category (e.g. 90% versus 20% identity for "sequence similarity" or a two-hybrid result versus co- purification over several columns for "physical interaction")." Ever since the second annotation camp, I've been thinking that maybe we should ditch this altogether. Every time the group has discussed the relative reliability/confidence of the evidence codes, it is apparent that one's confidence depends on which type of IMP/IGI/IDA/ISS/etc and on which author. We have come to the conclusion multiple times that the evidence code does not correlate with one's confidence in the annotation. Thus, I think that this "loose hierarchy of reliability" is a holdover from the early days of GO before we had come to the conclusion that one cannot make statements of reliability based on the evidence code. Further, I think that keeping this "loose hierarchy of reliability" in our documentation encourages people to do/say things like "Well, this is a good annotation, so I don't want to give it NAS, I'd rather give it TAS." The evidence codes should be applied purely on the basis of what type of statement or experiment is made, with respect to whether it is a "better" code or not. If we get rid of the loose hierarchy, we can eliminate the "better" code idea. I think it might be more accurate to say something like there are two classes of codes: those assigned by curators and those assigned without any input from a human curator, and then we can divide the codes assigned by curators into another couple classes: experimental codes and author statement codes Curator Assigned Evidence codes: Experimental codes: IDA/IMP/IGI/IPI/ISS/IEP Author Statement codes: TAS/NAS Evidence code assigned withoug curator input: IEA and we'd need to figure out where to put the new code RCA, it might need it's own class under "curator assigned codes" -Karen Christie ---------------------------------------------------------------------- Comment By: kpilcher (kpilcher) Date: 2005-10-27 15:53 Message: Logged In: YES user_id=1056932 That would be great, thanks! ---------------------------------------------------------------------- Comment By: Valerie Wood (val_wood) Date: 2005-10-27 15:35 Message: Logged In: YES user_id=516865 I agree there should be a best practice. Now I am thinking about this more I will document new cases. At the moment I am reading thourough the documentation and the curation camp minutes (hence this SF deluge). There seem to be lots of 'unresolved' areas, maybe they will be discussed furhter at the next consortium meeting? When I have my draft SOP I'll sent it to you and Pascale and you can see if it sounds sensible ---------------------------------------------------------------------- Comment By: kpilcher (kpilcher) Date: 2005-10-27 15:28 Message: Logged In: YES user_id=1056932 Hmm...this is tricky. I agree that the IC annotation is more informative than the NAS annotation, however, as a curator I try to give credit to the published authors as much as possible. Perhaps you could keep both? This is definitely confusing and needs to be documented. I've been looking through the minutes from the last annotation camp and the distinction between IC and TAS (and sometimes NAS) is a recurring theme. Karen ---------------------------------------------------------------------- Comment By: Valerie Wood (val_wood) Date: 2005-10-27 15:18 Message: Logged In: YES user_id=516865 hmm it all gets a bit murky though. For many of these, I make an inference, then the inference gets published. Do I then change the IC to NAS and the paper because it is now published. It is still at this point only an inference based on other annotations, except now it is cited in a publication. I have noticed this for a few things recently....at least IC with the GO terms allows the user to see which pieces of information the inference was derived from. Perhaps with (GO:0005816|GO:0003674) should be allowed with NAS? ---------------------------------------------------------------------- Comment By: kpilcher (kpilcher) Date: 2005-10-27 15:06 Message: Logged In: YES user_id=1056932 It seems to me that NAS is the right one to use. It is an author statement but it's not traceable to anything except that statement. IC with a published reference seems a little strange since it's inferred by an author, not a curator. Karen ---------------------------------------------------------------------- Comment By: Valerie Wood (val_wood) Date: 2005-10-27 13:37 Message: Logged In: YES user_id=516865 I see why I used NAS for this rather than IC. The authors seem pretty convinced this is a membrane bound, they even mention it in the title: Two-hybrid search for proteins that interact with Sad1 and Kms1, two membrane-bound components of the spindle pole body in fission yeast. I used NAS as there is no direct experimental evidence (but I should of added the Pubmed ID. I only recently reilised I could use Pubmed IDs with NAS! I still don't know which evidence code would be best to capture this...... ---------------------------------------------------------------------- Comment By: Valerie Wood (val_wood) Date: 2005-10-27 13:32 Message: Logged In: YES user_id=516865 I have been thinking more recently about the NAS/TAS distinction. I think you are right that "If an author states a more granular function/process in a conclusion" and it seems reilistic enough to be captured it should get NAS. I think it is useful to annotate things which have no experimental verification in this way as they are annotations which a researcher would want to test experimentally. I use NAS for anything which I don't have experimental data for : conference abstracts (rarely) pers comm (more frequently), usually when publication is pendng Things I can see which are obvious/highly likely but I don't have a more suitable evidence code (see below). statments made by authors in papers which appear to be reasonable but don't have any direct experimental evidence. here is an example spindle pole body IDA (PMID:14655046) membrane ISS (GOC:unpublished) with CBS:TMHMM nuclear membrane NAS (GOC:unpublished) In this case I think I should change this to clarify where the inference came from and change to nuclear membrane IC (GO:0005816|GO:0003674) which is more informative. I think we discussed these more granular IC inferences from 2 existing GO terms on the annotation tracker at some point and agreed that this was OK (although i obviously haven't implemented it !) ---------------------------------------------------------------------- Comment By: kpilcher (kpilcher) Date: 2005-10-26 19:03 Message: Logged In: YES user_id=1056932 Hi Val, I've been having a hard time with TAS lately, re-evaluating how it's used. If an author states a more granular function/process in a conclusion, it's not traceable back to anything, and therefore this should not be TAS, but perhaps NAS instead? "...discussion sections should usually be regarded with greater skepticism." "With a few exceptions, TAS should be used only if references to the original work are available." Also, how do people feel about having a higher level term and a lower level term with the SAME evidence code and the SAME reference? I tend to think only the more granular term should be included when using the same ev code/same ref (but not for diff ev code/diff ref). Thanks for working on this, Karen ---------------------------------------------------------------------- You can respond by visiting: https://sourceforge.net/tracker/?func=detail&atid=600519&aid=1338308&group_id=36855 |
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From: SourceForge.net <no...@so...> - 2007-06-07 12:25:27
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GO website item #1732735, was opened at 2007-06-07 12:25 Message generated for change (Tracker Item Submitted) made by Item Submitter You can respond by visiting: https://sourceforge.net/tracker/?func=detail&atid=600519&aid=1732735&group_id=36855 Please note that this message will contain a full copy of the comment thread, including the initial issue submission, for this request, not just the latest update. Category: request feature Group: None Status: Open Resolution: None Priority: 3 Private: No Submitted By: Jane Lomax (jl242) Assigned to: Nobody/Anonymous (nobody) Summary: RSS feed? Initial Comment: (suggestion from Suzi from managers meeting) Can we have a GO RSS feed for new terms etc, that scrolls across the front page of the website somewhere? Will show people what a dynamic project we are! ---------------------------------------------------------------------- You can respond by visiting: https://sourceforge.net/tracker/?func=detail&atid=600519&aid=1732735&group_id=36855 |